HOME >> MEDICINE >> NEWS
Methylphenidate improves attention, behavior of children surviving leukemia, brain tumors

Children who suffer from behavioral and learning problems after their central nervous systems have been exposed to chemotherapy or radiation appear to benefit from treatment with methylphenidate (MPH), the drug commonly known by the brand name Ritalin. This finding, from investigators at St. Jude Children's Research Hospital, are published in the Dec. 1 issue of the Journal of Clinical Oncology (JCO).

The study suggests that MPH can at least temporarily reduce some of the attention and social deficits among survivors of childhood acute lymphoblastic leukemia (ALL) and brain tumors (BTs), the two most common forms of childhood cancer.

Previous studies have shown that these children are likely to develop significant cognitive and behavioral problems compared to their healthy peers, according to Raymond K. Mulhern, Ph.D., chief of St. Jude Behavioral Medicine. Mulhern is lead author of JCO report.

"Our three-week study gave us promising results for children suffering from attention and behavior problems due to their cancer treatments," Mulhern said. "Our future plans include follow-up evaluations of children who continue MPH treatment for three, six and 12 months. In addition to improvements in learning and behavior, we would also like to know if such treatment results in structural changes in the brain, as hypothesized by other researchers."

The St. Jude study is the first to examine the ability of two doses of MPH to reduce these problems at home and in the classroom among childhood cancer survivors.

The study included 83 long-term survivors, 40 of whom had survived ALL and 43 of whom survived BTs. The children (47 males and 36 females) were identified as having attention deficits as measured by specific tests and according to both parent and teacher reports. They ranged in age from six months to 14.3 years when they were first diagnosed with cancer, and 6.7 to 17.9 years when they were in
'"/>

Contact: Bonnie Cameron
bonnie.cameron@stjude.org
901-495-4815
St. Jude Children's Research Hospital
1-Dec-2004


Page: 1 2

Related medicine news :

1. Hormonal treatment improves survival in high-risk prostate cancer patients
2. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
3. New substance that improves the photodetection of bladder cancer gains market approval
4. Most advanced CT scanner improves imaging of heart, avoids need for surgical inspection
5. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
6. New test improves detection of bladder cancer
7. Adding radiation therapy to chemotherapy improves survival in patients with high-risk breast cancer
8. Care of rural stroke patients improves with telephone support
9. Acupuncture relieves pain and improves function in knee osteoarthritis
10. Daily social/physical activity improves sleep and cognition in the elderly
11. Stanford study finds new method improves chemotherapy survival in mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... ... has announced the Best Memory Care Facilities in Louisville, KY. The guide identifies ... amenities. , According to the Alzheimer’s Association , 5.6 million people ...
(Date:9/1/2020)... ... September 01, 2020 , ... Feeding Matters , the first organization in ... Disorder (PFD), is pleased to announce that the U.S. Centers for Disease Control and ... in the next edition of the U.S. International Classification of Diseases (ICD ) ...
(Date:8/31/2020)... ... ... Just found out your dear friend has cancer? , It’s hard to hear your doctor ... their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. , ... ways to help? Words are failing me. I’m scared. I want to DO something. , ...
(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., one of ... United States, today announced the grand opening of another affiliated Bright Now! ... enjoy convenient hours, a comfortable office, and full-service care at the new Beaumont ...
(Date:8/31/2020)... ... August 31, 2020 , ... Bonde Innovations, ... patients with advanced heart failure, today announced that the company has been awarded ... $555,358 from the National Heart, Lung, and Blood Institute of the National Institutes ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ANGELES (PRWEB) , ... August 28, 2020 , ... ... integrative medicine and aesthetic beauty, bringing a unique perspective and approach. Armed with ... Dr. Rahi ventured out to share her knowledge of the human body with ...
(Date:8/27/2020)... ... August 27, 2020 , ... The flu season is right round the corner and the ... with all the necessary measures before it begins to harbor its effects on us. Already ... is leaving a huge impact on our lives. Hence it has become even more relevant ...
(Date:8/27/2020)... ... 2020 , ... Bridge To A Cure Foundation announces the appointment of Henry ... neuro-oncologist who serves on the Board of Directors at The Preston Robert Tisch Brain ... , Internationally recognized, Dr. Friedman is a widely published author of more than 500 ...
Breaking Medicine Technology:
Cached News: