Mild noise damage can be detected by cells in the inner ear

Damage to the inner ear as a result of environmental noise is a major cause of deafness in the developed world. In new research, scientists now report evidence that the delicate sensory hair cells of the inner ear might react to being damaged by triggering calcium signals in surrounding tissues. The findings help further our understanding of how the ear reacts to damage, not only by loud, prolonged noise, but also by loud sound for just short periods the kind of sound we are subjected to every day in noisy streets and trains, in workplaces, and in the use of personal audio players.

The researchers, Dr. Jonathan Gale of University College London, and Valeria Piazza, Catalin Ciubotaru and Dr. Fabio Mammano of the Venetian Institute of Molecular Medicine in Padova, have found that adenosine triphosphate, otherwise known as ATP, can activate a cascade of signals in tissues of the inner ear. Gale and colleagues found that when deliberately damaged, the sensory receptor cells of the hearing organ, the cochlea, released ATP, which then produced a wave of a critical cellular messenger, calcium ions, that spread from the cells surrounding the damaged cell to other cells in the inner ear. It turns out that the inner ear cells were extremely sensitive to ATP, and may well express an as yet unknown novel receptor for ATP. Rather than trying to study this subtle process in live animals, the work was done using tissue preparations, but published experiments from another ear research group have shown that the levels of ATP inside the ears of animals exposed to loud (110 dB SPL) noise for only 15 minutes increased to just the right amount to activate the mechanism described in the new work.

The authors note that much work is required to understand the effects of elevating ATP concentration in the inner ear. Nonetheless, the noise levels required to activate this mechanism are just those that would be heard in nightclubs and in particular when using personal headp

Contact: Heidi Hardman
Cell Press

Page: 1 2

Related medicine news :

1. Women exposed to frustrating noise stress snack more afterwards
2. UB, military collaborate on design, testing of first drug to prevent noise-induced hearing loss
3. Airport noise impairs long-term memory and reading
4. Researchers devise ways to reduce noise, improve sleep in nursing homes
5. New hearing test simulates noise of real world
6. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
7. Research offers hope of new treatments for liver damage
8. Traffic fumes damage DNA
9. Does the college experience damage your brain?
10. Mothers exposure to air pollutants linked to chromosome damage in babies
11. Cooling lessens brain damage in sick newborn babies

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: