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Most children with acute sinusitis recover without antibiotics

t of those on the placebo. Side effects such as nausea and diarrhea were more common among the children taking an antibiotic, appearing in 19 percent of those on amoxicillin, 11 percent of those on amoxicillin-clavulanate and 10 percent of the placebo group.

Some patients who improved initially then relapsed after three or four weeks. Other patients symptoms reappeared in the second month after treatment began. However there were no differences among the three groups.

"In a sense, we have met the enemy, and we are it," says Elliot Gellman, M.D., clinical professor of pediatrics. "Many people who come into the office say they are there to get antibiotics for sinus problems."


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Contact: Anne Enright Shepherd
shepherda@msnotes.wustl.edu
314-286-0119
Washington University School of Medicine
1-Apr-2001


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