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Mount Sinai stroke prevention trial published in JAMA

. Approximately 15 percent of all strokes occur in people with AF. Age, high blood pressure, diabetes and congestive heart failure further increase the risk of stroke in patients with AF. Patients with AF also tend to have more disabling strokes compared to those without AF. In fact, among patients who suffer a stroke, people with AF are 70 percent more likely to die than people without AF.

Stroke risk in patients with AF can be reduced by more than 60 percent using oral anticoagulant therapy such as warfarin. However, many eligible patients are not receiving oral anticoagulant therapy. Warfarin interacts with many foods and medications, requiring frequent blood test monitoring and dose adjustments to prevent excessive bleeding or inadequate anticoagulation.


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Contact: Mount Sinai Press Office
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8-Feb-2005


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