HOME >> MEDICINE >> NEWS
Mouse antibodies thwart SARS virus

NOTE TO REPORTERS/EDITORS: The embargo for this release has been lifted.The mouse immune system develops antibodies capable of single-handedly neutralizing the SARS virus, researchers at the National Institute of Allergy and Infectious Diseases (NIAID) report in the April 1 issue of the Journal of Virology, available online March 12. NIAID is part of the National Institutes of Health (NIH).

This discovery affirms that researchers developing vaccines that trigger antibodies to the SARS virus are heading in the right direction. Vaccines can stimulate the immune system to produce antibodies or specialized cells or both to stop invading viruses.

"Since SARS emerged in people in late 2002, global public health experts have been anxiously awaiting a vaccine for this potentially fatal respiratory ailment. Knowing which arm of the immune system to trigger brings us one step closer to that goal," says NIAID Director Anthony S. Fauci, M.D.

"This is good news for people developing vaccines that would prime the immune system to produce antibodies against the SARS virus," says Kanta Subbarao, M.D., an investigator in NIAID's Laboratory of Infectious Diseases and lead author on the study. "Our results also indicate that drug researchers can use laboratory mice as a model to evaluate whether a drug blocks SARS." Both findings could help lessen the time it takes to develop an effective vaccine or antiviral drugs for SARS.

In collaboration with colleagues at the Centers for Disease Control and Prevention and the NIH Clinical Center, Dr. Subbarao's team examined whether mice could be infected with the SARS virus and if so, how the mouse immune system responded. Initial experiments revealed that while the SARS virus did not make the mice sick, it was able to infect cells lining mouse airways and lungs to reproduce itself.

Next, the NIAID team gave a subset of the mice a second dose of the SARS virus 28 days later. This time they found
'"/>

Contact: Linda Joy
ljoy@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
12-Mar-2004


Page: 1 2

Related medicine news :

1. Mouse model reveals potential way to reduce cardiac deaths in kidney patients
2. Mouse gene shows new mechanism behind cardiac infarction in man
3. Mouse model gives insight to human hair loss
4. Mouse study: Signal overload in Alzheimer brains
5. Mouse shows how Rituximab removes human B cells
6. Mouse study could aid vaccine designers
7. Mouse model mimics real-world plague infection
8. Mouse model of neuromuscular disease identifies key player in motor neuron death
9. Mouse study gives new view of anthrax toxin
10. Mouse studies reveal immune mechanism involved in bone loss caused by estrogen deficiency
11. Mouse provides clues about chronic pain

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... , ... North Cypress Medical Center hosted its 9th Annual Spring ... the help of community partners, the event organizers raised $45,000 for the Lone ... members and their families through health, wellness, and therapeutic support. , A special ...
(Date:5/26/2016)... ... May 26, 2016 , ... The MIAMI Institute for Age Management ... Dr. Adonis Maiquez MD, ABAARM. Dr. Adonis , Wellness Physician of the MIAMI ... member of the Institute for Functional Medicine. , He also heads up FITTLab, the ...
(Date:5/26/2016)... ... May 26, 2016 , ... Bunion Bootie , the ... bunionette) treatment was more than humbled by customer demand over the Mother’s Day Weekend ... mid sale. Now that Bunion Bootie has completely replenished its inventory levels, it hopes ...
(Date:5/26/2016)... ... May 26, 2016 , ... A health conscious snack ... The Dough Bar, has ignited an undeniable buzz in the protein product community ... not just any doughnut.  These doughnuts are packed with 11 grams of protein and ...
(Date:5/26/2016)... ... 2016 , ... Metcalf & Associates’ Maureen Metcalf ... in leading technology and human resources operations for health care, education, banking, and ... featured on Metcalf’s VoiceAmerica radio show , Innovative Leaders Driving Thriving Organizations. ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... and GERMANTOWN, Maryland , May 25, ... QGEN ; Frankfurt Prime Standard: QIA) today announced that the ... Therawis Diagnostics GmbH to develop and commercialize predictive assays in ... PITX2 as a marker to predict effectiveness of anthracycline treatment ... "We are pleased to partner with Therawis, which developed ...
(Date:5/25/2016)... NEW YORK , May 25, 2016 ... Device Market Size, Share, Development, Growth and Demand Forecast ... Insulin Syringe, Insulin Pump and Others)" published by P&S ... valued at $9,998.3 million in 2015, and it is ... 2016-2022. Based on type, the insulin pump segment is ...
(Date:5/25/2016)... Digital Health Dialog, LLC dba EngagedMedia ... US Patent and Trademark Office of U.S. Patent ... for electronic opt-­in and processing of discount coupons ... compliance and otherwise. Logo - http://photos.prnewswire.com/prnh/20160524/371583LOGO ... "Our technology allows for individuals to opt­-in to ...
Breaking Medicine Technology:
Cached News: