HOME >> MEDICINE >> NEWS
Mouse antibodies thwart SARS virus

NOTE TO REPORTERS/EDITORS: The embargo for this release has been lifted.The mouse immune system develops antibodies capable of single-handedly neutralizing the SARS virus, researchers at the National Institute of Allergy and Infectious Diseases (NIAID) report in the April 1 issue of the Journal of Virology, available online March 12. NIAID is part of the National Institutes of Health (NIH).

This discovery affirms that researchers developing vaccines that trigger antibodies to the SARS virus are heading in the right direction. Vaccines can stimulate the immune system to produce antibodies or specialized cells or both to stop invading viruses.

"Since SARS emerged in people in late 2002, global public health experts have been anxiously awaiting a vaccine for this potentially fatal respiratory ailment. Knowing which arm of the immune system to trigger brings us one step closer to that goal," says NIAID Director Anthony S. Fauci, M.D.

"This is good news for people developing vaccines that would prime the immune system to produce antibodies against the SARS virus," says Kanta Subbarao, M.D., an investigator in NIAID's Laboratory of Infectious Diseases and lead author on the study. "Our results also indicate that drug researchers can use laboratory mice as a model to evaluate whether a drug blocks SARS." Both findings could help lessen the time it takes to develop an effective vaccine or antiviral drugs for SARS.

In collaboration with colleagues at the Centers for Disease Control and Prevention and the NIH Clinical Center, Dr. Subbarao's team examined whether mice could be infected with the SARS virus and if so, how the mouse immune system responded. Initial experiments revealed that while the SARS virus did not make the mice sick, it was able to infect cells lining mouse airways and lungs to reproduce itself.

Next, the NIAID team gave a subset of the mice a second dose of the SARS virus 28 days later. This time they found
'"/>

Contact: Linda Joy
ljoy@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
12-Mar-2004


Page: 1 2

Related medicine news :

1. Mouse model reveals potential way to reduce cardiac deaths in kidney patients
2. Mouse gene shows new mechanism behind cardiac infarction in man
3. Mouse model gives insight to human hair loss
4. Mouse study: Signal overload in Alzheimer brains
5. Mouse shows how Rituximab removes human B cells
6. Mouse study could aid vaccine designers
7. Mouse model mimics real-world plague infection
8. Mouse model of neuromuscular disease identifies key player in motor neuron death
9. Mouse study gives new view of anthrax toxin
10. Mouse studies reveal immune mechanism involved in bone loss caused by estrogen deficiency
11. Mouse provides clues about chronic pain

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension ... that it will receive two significant new grants to support its work to ... its 25th anniversary by recognizing patients, medical professionals and scientists for their work ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... 24, 2016 , ... Puradigm® & Innovative Solutions today announced ... and processing operations at its production facility, and opened its first two dispensaries ... manufacturer of a complete system of proactive air and surface purification solutions for ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, ... Board will take whatever measures required to build a ... stock which is currently listed on the OTC Markets-pink ... Company Chairman and CEO, "We are seeing an anomaly ... to understand, not only by the Company, but shareholders ...
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
Breaking Medicine Technology:
Cached News: