HOME >> MEDICINE >> NEWS
Mouse antibodies thwart SARS virus

NOTE TO REPORTERS/EDITORS: The embargo for this release has been lifted.The mouse immune system develops antibodies capable of single-handedly neutralizing the SARS virus, researchers at the National Institute of Allergy and Infectious Diseases (NIAID) report in the April 1 issue of the Journal of Virology, available online March 12. NIAID is part of the National Institutes of Health (NIH).

This discovery affirms that researchers developing vaccines that trigger antibodies to the SARS virus are heading in the right direction. Vaccines can stimulate the immune system to produce antibodies or specialized cells or both to stop invading viruses.

"Since SARS emerged in people in late 2002, global public health experts have been anxiously awaiting a vaccine for this potentially fatal respiratory ailment. Knowing which arm of the immune system to trigger brings us one step closer to that goal," says NIAID Director Anthony S. Fauci, M.D.

"This is good news for people developing vaccines that would prime the immune system to produce antibodies against the SARS virus," says Kanta Subbarao, M.D., an investigator in NIAID's Laboratory of Infectious Diseases and lead author on the study. "Our results also indicate that drug researchers can use laboratory mice as a model to evaluate whether a drug blocks SARS." Both findings could help lessen the time it takes to develop an effective vaccine or antiviral drugs for SARS.

In collaboration with colleagues at the Centers for Disease Control and Prevention and the NIH Clinical Center, Dr. Subbarao's team examined whether mice could be infected with the SARS virus and if so, how the mouse immune system responded. Initial experiments revealed that while the SARS virus did not make the mice sick, it was able to infect cells lining mouse airways and lungs to reproduce itself.

Next, the NIAID team gave a subset of the mice a second dose of the SARS virus 28 days later. This time they found
'"/>

Contact: Linda Joy
ljoy@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
12-Mar-2004


Page: 1 2

Related medicine news :

1. Mouse model reveals potential way to reduce cardiac deaths in kidney patients
2. Mouse gene shows new mechanism behind cardiac infarction in man
3. Mouse model gives insight to human hair loss
4. Mouse study: Signal overload in Alzheimer brains
5. Mouse shows how Rituximab removes human B cells
6. Mouse study could aid vaccine designers
7. Mouse model mimics real-world plague infection
8. Mouse model of neuromuscular disease identifies key player in motor neuron death
9. Mouse study gives new view of anthrax toxin
10. Mouse studies reveal immune mechanism involved in bone loss caused by estrogen deficiency
11. Mouse provides clues about chronic pain

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... ... April 28, 2016 , ... Amada Senior Care, premier provider ... in San Antonio – its San Antonio West location. Prior to entering the senior ... sales. The grand opening of Amada San Antonio West will take place on Friday, ...
(Date:4/28/2016)... ... April 28, 2016 , ... The American Society for ... developers of the AnzuMedical™ Knowledge Sharing and Collaboration Platform™ , today announced ... platform is scheduled to launch in July 2016 and will be a combined ...
(Date:4/28/2016)... ... April 28, 2016 , ... ... development of miniature microphones and headsets announced today that the US Patent Office ... integrating in-earphones into a structure. This innovative design creates a lightweight and modular ...
(Date:4/28/2016)... Philadelphia, PA (PRWEB) , ... April 28, 2016 ... ... Barbara Browne, M.D. has been named a Top Doc in Physical Medicine and ... in conjunction with Castle Connolly Medical, Ltd. by randomly surveying physicians and medical ...
(Date:4/28/2016)... ... April 28, 2016 , ... Metabolic Nutrition today ... this week’s 2016 Europa Games Get Fit and Sports Expo in Orlando, ... Europa Orlando Expo coming up April 29-30, was selected as the perfect event to ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... -- Dr. Vivek Ahuja , ... Ste phen Schmidt Join ... cloud-based software solutions for life sciences, today announced key new leaders ... of insight to a growing business.  This will bolster the company,s ... Phillips joined ArisGlobal in the position of Vice President - ...
(Date:4/28/2016)... 2016 New market research ... a report that provides an overview of the ... by identifying new targets and MOAs to produce ... discussed in this H1 2016 Osteoarthritis Pipeline report ... Inc., Abiogen Pharma S.p.A., Ablynx NV, Achelios Therapeutics, ...
(Date:4/27/2016)... 2016 Elekta today announced that ... be the focal point of seven scientific presentations at ... for Radiotherapy & Oncology, taking place April 29 - ... radiotherapy system and a high-field MRI scanner with sophisticated ... patient,s anatomy in real time. The MR-linac is designed ...
Breaking Medicine Technology:
Cached News: