HOME >> MEDICINE >> NEWS
NIAID forms network to tackle potentially fatal reaction to smallpox vaccine

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), today launched the Atopic Dermatitis and Vaccinia Network (ADVN), a nationwide research group that seeks to reduce the risk of eczema vaccinatum (EV), a severe and potentially deadly complication of smallpox immunization. EV occurs almost exclusively in people with a history of atopic dermatitis (AD), a chronic, itchy skin condition commonly referred to as eczema. While uncommon, EV can develop when AD patients are given the smallpox vaccine or come into close personal contact with people who recently received the vaccine. If untreated, EV can kill between 1 to 6 percent of those affected. In children younger than 2 years of age, EV has been estimated to kill up to 30 percent.

"Millions of Americans have a history of atopic dermatitis," says Anthony S. Fauci, M.D., director of NIAID. "Launching this network is an important step toward our goal of helping to protect everyone against the smallpox virus without the risk of life-threatening complications."

"Previous studies suggest that both innate and adaptive immunity are impaired in patients with atopic dermatitis, but the specific defects that increase the likelihood of eczema vaccinatum have yet to be explained," says Daniel Rotrosen, M.D., director of NIAID's Division of Allergy, Immunology and Transplantation. "The information generated by this network will improve our understanding of the immune responses of these patients and should greatly influence the design of a safer smallpox vaccine."

The ADVN comprises three integrated components: a clinical studies consortium, an animal studies consortium and a statistical and data coordinating center.

The ADVN Clinical Studies Consortium will, among other activities, seek to understand why people with AD have such severe reactions to smallpox vaccine by evaluating their immune responses after natural exposure to less harmf
'"/>

Contact: Paul Williams
pwilliams@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
19-May-2004


Page: 1 2

Related medicine news :

1. NIAID initiates trial of experimental avian flu vaccine
2. NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
3. NIAID begins enrolling volunteers for novel HIV vaccine study
4. NIAID-sponsored clinical trial aims to boost flu vaccine supply
5. NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
6. NIAID launches influenza genome sequencing project
7. NIAID launches program to improve medical tools against emerging infectious diseases
8. NIAID rotavirus vaccine licensed for commercialization
9. Second NIAID SARS vaccine candidate helps mice fend off SARS
10. NIAID vaccine protects against SARS virus infection in mice
11. NIAID Ebola vaccine enters human trial

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... The growing ... focus of Fall 2020 Virtual Conference, a two-day virtual event for radiology professionals ... & Beyond" is the follow-up to AuntMinnie.com's successful virtual event in spring 2020, ...
(Date:9/2/2020)... (PRWEB) , ... September 02, 2020 , ... ... enterprise software for healthcare payers administering Medicare Advantage and Special Needs plans, is ... presented by America’s Health Insurance Plans (AHIP). RAM is supporting the event as ...
(Date:9/1/2020)... Calif. (PRWEB) , ... September 01, 2020 , ... As ... “safe side”, the Cohn Health Institute has taken this time to expand ... celebration of its 30th Anniversary, the Cohn Health Institute will be relaunching its brand ...
(Date:8/31/2020)... ... August 31, 2020 , ... Just found out your dear friend has cancer? , ... your friend or family member shares their diagnosis. Once the shock wears off, the questions ... wrong thing? What are the best ways to help? Words are failing me. I’m scared. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global ... and affordable online education – is proud to announce its new master’s degree ... of its kind in the nation, the 60-credit hour program is designed to ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... Breast and ovarian cancers are common diseases that ... of breast cancers (about 7,500 women per year) and 10% of ovarian cancers (about ... Both genes are detectable in the Women’s Excellence Genetic Testing Program. , Dr. ...
(Date:8/31/2020)... ... 2020 , ... Continuing on its rapid national expansion - ... deodorization provider - is proud to announce it has opened doors in Phoenix, ... residents throughout the area. , Germinator provides a 100% safe and non-toxic sanitizing ...
(Date:8/28/2020)... ... 28, 2020 , ... Dr. Raheleh Sarbaziha has been reimagining ... approach. Armed with her qualifications from Ross University School of Medicine and the ... human body with the nation and world. With a fellowship in Integrative Medicine ...
Breaking Medicine Technology:
Cached News: