HOME >> MEDICINE >> NEWS
NIAID launches program to improve medical tools against emerging infectious diseases

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded 14 contracts totaling more than $73 million to fund the Large-Scale Antibody and T Cell Epitope Discovery Program, an initiative aimed at quickly identifying the regions of selected infectious agents that elicit immune reactions. The study of these regions, known as epitopes, promises to uncover targets for new and improved vaccines, therapies and diagnostic tools against potential bioterror agents as well as emerging/re-emerging infectious diseases such as West Nile virus and influenza. NIAID will make information on each newly identified epitope freely available to scientists through a searchable online database currently under development.

"Elucidating the basic mechanisms of immune function is a major focus of our biodefense research agenda," says Anthony S. Fauci, M.D., director of NIAID. "The information generated by this program will deepen our understanding of how components of the immune system defend against certain infectious agents, enabling researchers to design new and improved medical countermeasures."

"Researchers have been conducting epitope discovery for many years, but generally on a small scale," says Daniel Rotrosen, M.D., director of NIAID's Division of Allergy, Immunology and Transplantation. "This initiative, however, will yield new knowledge about antigenic epitopes from a wide variety of microbes, including agents that might be used in a bioterrorist attack."

Epitopes are recognized by the body's B and T cells, white blood cells that detect an invading pathogen. Each B and T cell is specific for a particular antigen, meaning that each can only bind to a certain foreign molecular structure. This "specificity" is determined by the receptors on the surface of each cell.

Both B- and T-cell specificity as well as the diverse functions of these cells determine the effectiveness of an immu
'"/>

Contact: Paul Williams
pw81y@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
1-Nov-2004


Page: 1 2 3

Related medicine news :

1. NIAID initiates trial of experimental avian flu vaccine
2. NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
3. NIAID begins enrolling volunteers for novel HIV vaccine study
4. NIAID-sponsored clinical trial aims to boost flu vaccine supply
5. NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
6. NIAID launches influenza genome sequencing project
7. NIAID forms network to tackle potentially fatal reaction to smallpox vaccine
8. NIAID rotavirus vaccine licensed for commercialization
9. Second NIAID SARS vaccine candidate helps mice fend off SARS
10. NIAID vaccine protects against SARS virus infection in mice
11. NIAID Ebola vaccine enters human trial

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... August 05, 2020 , ... In its often-heroic ... unprecedented challenges. Regardless of the obstacle - shortages of tests, ventilators and ICU ... the cancellation or postponement of all nonessential services - providers across the country ...
(Date:8/5/2020)... ... ... CentrAlert, Inc. today announced the launch of their free ... NOW!, which is available for Apple and Android , seeks to ... application. , “When COVID-19 first hit, there was so much that we didn’t know,” ...
(Date:8/5/2020)... ... 04, 2020 , ... Today, Power to Decide’s One Key Question ... 2020 Innovation Station Best Practice Award. The One Key Question program is a transformative ... pregnant and have a child. One Key Question is used by thousands of health ...
(Date:8/3/2020)... CHICAGO and FORT WORTH, Texas (PRWEB) , ... ... ... clinical stage biopharmaceutical company, today announced enrollment of the first patients with first-line ... arm of the ongoing phase 1/2 1801 trial of 9-ING-41, (NCT03678883, EudraCT#:2018-003739-32). ...
(Date:7/31/2020)... ... 2020 , ... National Association of Chain Drug Stores (NACDS) ... nation’s ongoing preparations for the eventual deployment of COVID-19 vaccines: , “By any ... essential component of vaccine deployment. They will need to be part of the ...
Breaking Medicine News(10 mins):
(Date:7/10/2020)... WINNIPEG, Manitoba (PRWEB) , ... July 10, 2020 ... ... a global medical device company and advanced manufacturing solutions provider today announced that ... Health Canada approval. , The Company has engineered a new 3D-printed swab design ...
(Date:7/10/2020)... ... July 09, 2020 , ... The team at ... to their completely redesigned website. The new site offers a multitude of user enhancements ... free downloadable information available with easy to navigate menus which will allow patients to ...
(Date:7/7/2020)... ... July 07, 2020 , ... CHESS Health, the ... the leading comprehensive platform for online education on mental health, substance use, and ... Substance Use Disorder (SUD) patients throughout each step of the treatment process. , ...
Breaking Medicine Technology:
Cached News: