HOME >> MEDICINE >> NEWS
NIAID launches program to improve medical tools against emerging infectious diseases

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded 14 contracts totaling more than $73 million to fund the Large-Scale Antibody and T Cell Epitope Discovery Program, an initiative aimed at quickly identifying the regions of selected infectious agents that elicit immune reactions. The study of these regions, known as epitopes, promises to uncover targets for new and improved vaccines, therapies and diagnostic tools against potential bioterror agents as well as emerging/re-emerging infectious diseases such as West Nile virus and influenza. NIAID will make information on each newly identified epitope freely available to scientists through a searchable online database currently under development.

"Elucidating the basic mechanisms of immune function is a major focus of our biodefense research agenda," says Anthony S. Fauci, M.D., director of NIAID. "The information generated by this program will deepen our understanding of how components of the immune system defend against certain infectious agents, enabling researchers to design new and improved medical countermeasures."

"Researchers have been conducting epitope discovery for many years, but generally on a small scale," says Daniel Rotrosen, M.D., director of NIAID's Division of Allergy, Immunology and Transplantation. "This initiative, however, will yield new knowledge about antigenic epitopes from a wide variety of microbes, including agents that might be used in a bioterrorist attack."

Epitopes are recognized by the body's B and T cells, white blood cells that detect an invading pathogen. Each B and T cell is specific for a particular antigen, meaning that each can only bind to a certain foreign molecular structure. This "specificity" is determined by the receptors on the surface of each cell.

Both B- and T-cell specificity as well as the diverse functions of these cells determine the effectiveness of an immu
'"/>

Contact: Paul Williams
pw81y@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
1-Nov-2004


Page: 1 2 3

Related medicine news :

1. NIAID initiates trial of experimental avian flu vaccine
2. NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
3. NIAID begins enrolling volunteers for novel HIV vaccine study
4. NIAID-sponsored clinical trial aims to boost flu vaccine supply
5. NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
6. NIAID launches influenza genome sequencing project
7. NIAID forms network to tackle potentially fatal reaction to smallpox vaccine
8. NIAID rotavirus vaccine licensed for commercialization
9. Second NIAID SARS vaccine candidate helps mice fend off SARS
10. NIAID vaccine protects against SARS virus infection in mice
11. NIAID Ebola vaccine enters human trial

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... ... dear friend has cancer? , It’s hard to hear your doctor say the words “You ... shock wears off, the questions and fears can be overwhelming. , How should I respond? ... are failing me. I’m scared. I want to DO something. , We’ve talked to experts ...
(Date:8/31/2020)... ... 2020 , ... Want to get moving, break up your routine, and make ... thrilled to launch its fourth annual STEPtember campaign in the United States to raise ... wherever they are at this moment — encouraging people to move in the ways ...
(Date:8/31/2020)... Colo. (PRWEB) , ... August 31, 2020 , ... ... provider of innovative higher-learning opportunities through high-quality, career-relevant, and affordable online education – ... Responder Psychology . , Among the first of its kind in the ...
(Date:8/31/2020)... ... ... and topsy-turvy economic outlook continues to put financial strain on many of us, so it ... from our monthly expenses and put more into savings, if possible. , “That’s a great ... safety net in place in case something were to happen to you,” says Lee Duncan, ...
(Date:8/31/2020)... CHICAGO (PRWEB) , ... August 31, 2020 , ... In ... Chicago West Loop is donating 10 percent of each hotel room booked with ... House Charities® of Chicagoland & Northwest Indiana (RMHC-CNI) , effective immediately. Donations will ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... August 26, 2020 , ... ScripHessco has ... Injuries. The infographic breaks down ways that chiropractors can help heal sports injuries ... to ScripHessco “Athletes have an unusual amount of pressure and stress on their ...
(Date:8/26/2020)... ... August 26, 2020 , ... ... expands its technology footprint with the addition of Novocyte Quanteon™ as a ... biomarker solutions, complemented with traditional ligand-binding assays and study management services, clients ...
(Date:8/26/2020)... ... August 26, 2020 , ... Clinical ... definitive agreement to acquire ProCE, a nationally recognized provider of continuing education ... , CEA represents a growing alliance of CME/CE and service organizations that ...
Breaking Medicine Technology:
Cached News: