HOME >> MEDICINE >> NEWS
NIAID launches program to improve medical tools against emerging infectious diseases

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded 14 contracts totaling more than $73 million to fund the Large-Scale Antibody and T Cell Epitope Discovery Program, an initiative aimed at quickly identifying the regions of selected infectious agents that elicit immune reactions. The study of these regions, known as epitopes, promises to uncover targets for new and improved vaccines, therapies and diagnostic tools against potential bioterror agents as well as emerging/re-emerging infectious diseases such as West Nile virus and influenza. NIAID will make information on each newly identified epitope freely available to scientists through a searchable online database currently under development.

"Elucidating the basic mechanisms of immune function is a major focus of our biodefense research agenda," says Anthony S. Fauci, M.D., director of NIAID. "The information generated by this program will deepen our understanding of how components of the immune system defend against certain infectious agents, enabling researchers to design new and improved medical countermeasures."

"Researchers have been conducting epitope discovery for many years, but generally on a small scale," says Daniel Rotrosen, M.D., director of NIAID's Division of Allergy, Immunology and Transplantation. "This initiative, however, will yield new knowledge about antigenic epitopes from a wide variety of microbes, including agents that might be used in a bioterrorist attack."

Epitopes are recognized by the body's B and T cells, white blood cells that detect an invading pathogen. Each B and T cell is specific for a particular antigen, meaning that each can only bind to a certain foreign molecular structure. This "specificity" is determined by the receptors on the surface of each cell.

Both B- and T-cell specificity as well as the diverse functions of these cells determine the effectiveness of an immu
'"/>

Contact: Paul Williams
pw81y@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
1-Nov-2004


Page: 1 2 3

Related medicine news :

1. NIAID initiates trial of experimental avian flu vaccine
2. NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
3. NIAID begins enrolling volunteers for novel HIV vaccine study
4. NIAID-sponsored clinical trial aims to boost flu vaccine supply
5. NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
6. NIAID launches influenza genome sequencing project
7. NIAID forms network to tackle potentially fatal reaction to smallpox vaccine
8. NIAID rotavirus vaccine licensed for commercialization
9. Second NIAID SARS vaccine candidate helps mice fend off SARS
10. NIAID vaccine protects against SARS virus infection in mice
11. NIAID Ebola vaccine enters human trial

Post Your Comments:
(Date:11/26/2014)... Aurora, CO (PRWEB) November 26, 2014 For ... fast, the new LES MILLS BODYPUMP™ classes at ... be just the workout they've been looking for. The 45- ... with CU Anschutz Health and Wellness Center fitness club memberships. ... muscles. The workouts are fast-paced and are aimed at fast ...
(Date:11/26/2014)... November 26, 2014 News Facts ... expanded capabilities at RSNA 2014 in Chicago. The ... and share diagnostic images, photos, videos and documents ... booth #8107 will learn more about these innovative ... technologies and partner initiatives – that enable more ...
(Date:11/26/2014)... of the most important and vital decisions a woman ... choosing the ideal wedding dress and bridesmaid dresses. BellasDress.com ... quality outfits. Today, BellasDress.com has unveiled its new range ... suitable bridesmaid gowns here at discount prices. , Formal ... and highlight all their most beautiful features while drawing ...
(Date:11/26/2014)... News) -- Vultures have developed highly specialized ways of ... dead animals, researchers report. The new research investigated ... and in the guts of 50 turkey vultures and ... faces of the vultures had more than 500 different ... the study found. The findings suggest that a ...
(Date:11/26/2014)... number of emergency department visits in the United States rose ... million in 2011, according to the U.S. Centers for Disease ... people were going to ERs with non-urgent medical needs: 96 ... two hours of arriving at the ER. In 2010, that ... percent of patients arrived at the ER after normal business ...
Breaking Medicine News(10 mins):Health News:LES MILLS BODYPUMP™ classes come to the University of Colorado Anschutz Health and Wellness Center 2Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 2Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 3Health News:Royal Blue Bridesmaid Dresses Now Are Available for Christmas at BellasDress.com 2Health News:ER Visits on the Rise, Study Reports 2
(Date:11/26/2014)... Pa. , Nov. 25, 2014  Unilife Corporation ... of injectable drug delivery systems, today announced that its ... to present at the Piper Jaffray 26th Annual Healthcare ... a.m. EST on Tuesday, December 2, 2014. ... Internet as a "live" listen only Webcast. To listen, ...
(Date:11/26/2014)... HERZLIYA PITUACH, Israel, Nov. 25, 2014 Immune ... a clinical stage biopharmaceutical company that engages in ... the treatment of inflammatory diseases and cancer, today ... public offering of 3,450,000 units, with each unit ... stock, par value $0.0001 per share, and one ...
(Date:11/24/2014)... Nov. 24, 2014  Arena Pharmaceuticals, Inc. (NASDAQ: ... a corporate overview and update at the Piper Jaffray 26 ... at 8:30 a.m. Eastern Time (5:30 a.m. Pacific Time), at ... . A live audio webcast of the ... Arena,s website at www.arenapharm.com . A replay of the ...
Breaking Medicine Technology:Unilife to Present at the Piper Jaffray 26th Annual Healthcare Conference on December 2nd 2Immune Pharmaceuticals Inc. Announces Closing Of Public Offering Of Common Stock And Warrants 2Immune Pharmaceuticals Inc. Announces Closing Of Public Offering Of Common Stock And Warrants 3Immune Pharmaceuticals Inc. Announces Closing Of Public Offering Of Common Stock And Warrants 4Immune Pharmaceuticals Inc. Announces Closing Of Public Offering Of Common Stock And Warrants 5Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 3
Cached News: