"If the drug is approved for human use, we can start clinical trials as soon as the go-ahead is given," Kobayashi said.
Diagnosis of prostate cancer with intact tissue magnetic resonance spectroscopy: Abstract No. 1069
Distinct molecular 'fingerprints' uniquely produced by cancerous prostate cells indicate how aggressive the disease is in individual patients, a team of Harvard University scientists revealed today.
"Cancerous prostate cells produce molecular metabolic 'fingerprints' that differ from the metabolic 'fingerprints' of healthy prostate cells," said Leo L. Cheng, Ph.D., Massachusetts General Hospital, Harvard Medical School.
"Through the use of proton magnetic resonance spectroscopy technology with high resolution magic angle spinning, we were able to distinguish between healthy and cancerous tissues according to their metabolic changes," he added. The technology is more powerful and precise than conventional histological measures.
By reading the metabolic portrait from prostate samples, the Harvard/MGH research team was able to determine the tumor aggressiveness. Magnetic resonance spectroscopy analysis of the tissue metabolic fingerprint correlated with the patient clinical status, such as the overall pathological features and stages.
This advance in technology can provide valuable information to patients and their clinicians before making treatment decisions regarding choices among surgery, chemotherapy, and radiation for prostate cancer.
Carrier albumin's binders in serum (CAB's): Detecting ovarian cancer: Abstract No. 4774
A unique set of proteins produced by ovarian cancer cells serves as a signature for malignancy and may translate to powerful early detectio
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Contact: Aimee Frank
amf@spectrumscience.com
202-955-6222
American Association for Cancer Research
28-Mar-2004