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National Institute on Aging, industry launch Alzheimer's disease neuroimaging initiative

The National Institute on Aging (NIA) in conjunction with other Federal agencies, private companies and organizations today launched a $60 million, 5-year public-private partnership -- the Alzheimer's Disease Neuroimaging Initiative -- to test whether serial magnetic resonance imaging (MRI), positron emission tomography (PET), other biological markers, and clinical and neuropsychological assessment can be combined to measure the progression of mild cognitive impairment (MCI) and early Alzheimer's disease (AD).

The study could help researchers and clinicians develop new treatments and monitor their effectiveness as well as lessen the time and cost of clinical trials. The project is the most comprehensive effort to date to find neuroimaging and other biomarkers for the cognitive changes associated with MCI and AD.

Within the Federal Government, the NIA is joined in the partnership by another National Institutes of Health (NIH) Institute--the National Institute of Biomedical Imaging and Bioengineering (NIBIB) -- and by the Food and Drug Administration, all of which are part of the U.S. Department of Health and Human Services. The Foundation for NIH is managing corporate and other private participation, and has received commitments totaling more than $20 million in contributions from the following companies and organizations: Pfizer Inc, Wyeth Research, Eli Lilly and Company, Merck & Co, Inc., GlaxoSmithKline, AstraZeneca AB, Novartis Pharmaceuticals Corporation., Eisai Global Clinical Development, Elan Corporation, plc, the Institute for the Study of Aging (ISOA) and the Alzheimer's Association. About two-thirds of the funding is expected to come from the Federal Government while private partners are expected to make up the other third. Ancillary studies will be funded by additional NIH grants.

"This is an extraordinary pooling of talent and resources toward a common goal -- delaying or preventing Alzheimer's disease," says Richard J. Hodes, M.D., Di
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Contact: Vicky Cahan or Doug Dollemore
dollemod@nia.nih.gov
301-496-1752
NIH/National Institute on Aging
13-Oct-2004


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