HOME >> MEDICINE >> NEWS
Nerve Cells Live Long And Talkative Lives In Sculpted Colonies On Silicon Chips

At a Texas meeting May 14, USC researcher Roberta Diaz Brinton will discuss her research and the hopes she has for the colonies of rat nerve cells she has cultured -- and even sculptured -- on silicon semiconductor substrate. She envisions that hybrid brain-electronic systems may soon serve to elucidate the process by which brains perform complex functions, including specific pattern recognition. Such systems may also form part of a new generation of chemical detectors.

Brinton, an associate professor of molecular pharmacology in the School of Pharmacy, also plans to use her wired colonies of cells for studies in her specialty, the study of the effects on the brain of the hormone estrogen and allied substances.

Finally and most ambitiously, Brinton and co-workers from the USC School of Engineering's department of biomedical engineering hope to someday be able to implant similar chips into living brains as both experimental instruments and eventually as prostheses.

The cells come from a part of the brain called the hippocampus, which is associated with short term memory. Brinton dissociates the cells from their intricate network of interconnections with each other, and then places them as individual cells on a specially prepared silicon testbed studded with a matrix of electrodes.

The dissociated cells, approximately 80,000 of them, affix themselves to the testbed and grow, sending out processes and reforming synaptic contacts with each other. They can live on the chips for extended periods -- as long as months, according to Brinton.

Brinton's lab is one of only a very few in the world able to culture and study such nerve cell colonies.

During the course of the nearly two years Brinton has been working with the technique of culturing on silicon, she and her co-worker, graduate student Walid Sassou have learned to make and use masks made by traditional photo-resist processes to "sculpt" the colonies into desired shapes by placement of the s
'"/>

Contact: Eric Mankin
mankin@usc.edu
213-740-9344
University of Southern California
13-May-1999


Page: 1 2 3

Related medicine news :

1. Nerve damage from alcoholism reversed after liver transplantation
2. Nerve navigation findings prompt new direction for spinal cord research
3. Vagus Nerve Stimulation Therapy (TM) more effective in epilepsy patients when used earlier
4. Cut Nerve Fibers Are Repaired In An Animal Model of Spinal Cord Injury; May Help Repair Nerve Damage In Humans
5. Percutaneous Electrical Nerve Stimulation May Offer Dramatic Short-Term Relief For Chronic Back Pain
6. Hunter College Biologist Marie Filbin Identifies Mechanism That Blocks All Inhibitors Of Nerve Regeneration; Breakthrough Reported In Neuron Magazine
7. Electrical Nerve Stimulation May Help Reduce Chronic Pain In Cancer Patients, Say UT Southwestern Researchers
8. Nerve Agent Sensor A Million Times More Sensitive
9. Study Shows Potential For Quelling AIDS Nerve Pain
10. Surprise! Cells have second source of phosphate
11. Cells from fat tissue turned into functional nerve cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Want to get moving, break ... Alliance Research Foundation (CPARF) is thrilled to launch its fourth annual STEPtember campaign in ... virtual challenge, STEPtember meets everyone wherever they are at this moment — encouraging people ...
(Date:8/31/2020)... Calif. (PRWEB) , ... August 31, 2020 , ... ... of business support services to dental groups in the United States, today announced ... the community of Beaumont, CA. , Patients will enjoy convenient hours, a ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/29/2020)... ... August 29, 2020 , ... When professor and author Randy Pausch ... than most people would. Rather than become melancholic, however, he put together a final ... one’s dreams. Randy Pausch took a negative situation and turned it into something that ...
(Date:8/28/2020)... Calif. (PRWEB) , ... August 28, 2020 , ... ... cover a one-year subscription to a customized Lighthouse Health & Wellness mobile app ... support of this project. Motorola Solutions Foundation awards grants each year to organizations, ...
Breaking Medicine News(10 mins):
(Date:8/31/2020)... ... ... you live in New York City you will always pay more for these two things: ... supply and demand, but are plastic surgeons in New York worth the premium prices that ... make the four-hour trip to have expert aesthetic treatments by some of the best doctors ...
(Date:8/28/2020)... ... August 28, 2020 , ... Dr. Mark Surrey has ... surgeon and serves as a clinical professor in the Department of OBGYN at UCLA’s ... Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical Director of Fellowship ...
(Date:8/27/2020)... ... 2020 , ... The flu season is right round the corner and the risk of getting ... necessary measures before it begins to harbor its effects on us. Already with the sudden ... huge impact on our lives. Hence it has become even more relevant to keep oneself ...
Breaking Medicine Technology:
Cached News: