Nerve Cells Live Long And Talkative Lives In Sculpted Colonies On Silicon Chips

At a Texas meeting May 14, USC researcher Roberta Diaz Brinton will discuss her research and the hopes she has for the colonies of rat nerve cells she has cultured -- and even sculptured -- on silicon semiconductor substrate. She envisions that hybrid brain-electronic systems may soon serve to elucidate the process by which brains perform complex functions, including specific pattern recognition. Such systems may also form part of a new generation of chemical detectors.

Brinton, an associate professor of molecular pharmacology in the School of Pharmacy, also plans to use her wired colonies of cells for studies in her specialty, the study of the effects on the brain of the hormone estrogen and allied substances.

Finally and most ambitiously, Brinton and co-workers from the USC School of Engineering's department of biomedical engineering hope to someday be able to implant similar chips into living brains as both experimental instruments and eventually as prostheses.

The cells come from a part of the brain called the hippocampus, which is associated with short term memory. Brinton dissociates the cells from their intricate network of interconnections with each other, and then places them as individual cells on a specially prepared silicon testbed studded with a matrix of electrodes.

The dissociated cells, approximately 80,000 of them, affix themselves to the testbed and grow, sending out processes and reforming synaptic contacts with each other. They can live on the chips for extended periods -- as long as months, according to Brinton.

Brinton's lab is one of only a very few in the world able to culture and study such nerve cell colonies.

During the course of the nearly two years Brinton has been working with the technique of culturing on silicon, she and her co-worker, graduate student Walid Sassou have learned to make and use masks made by traditional photo-resist processes to "sculpt" the colonies into desired shapes by placement of the s

Contact: Eric Mankin
University of Southern California

Page: 1 2 3

Related medicine news :

1. Nerve damage from alcoholism reversed after liver transplantation
2. Nerve navigation findings prompt new direction for spinal cord research
3. Vagus Nerve Stimulation Therapy (TM) more effective in epilepsy patients when used earlier
4. Cut Nerve Fibers Are Repaired In An Animal Model of Spinal Cord Injury; May Help Repair Nerve Damage In Humans
5. Percutaneous Electrical Nerve Stimulation May Offer Dramatic Short-Term Relief For Chronic Back Pain
6. Hunter College Biologist Marie Filbin Identifies Mechanism That Blocks All Inhibitors Of Nerve Regeneration; Breakthrough Reported In Neuron Magazine
7. Electrical Nerve Stimulation May Help Reduce Chronic Pain In Cancer Patients, Say UT Southwestern Researchers
8. Nerve Agent Sensor A Million Times More Sensitive
9. Study Shows Potential For Quelling AIDS Nerve Pain
10. Surprise! Cells have second source of phosphate
11. Cells from fat tissue turned into functional nerve cells

Post Your Comments:

(Date:7/10/2020)... PLEASANTON, Calif. (PRWEB) , ... July 09, 2020 ... ... (NYSE:TFX) focused on addressing unmet needs in the field of urology, today announced ... as a UroLift® Center of Excellence. The designation recognizes that Dr. Mercado has ...
(Date:7/10/2020)... ... 2020 , ... NeoTract, a wholly owned subsidiary of Teleflex ... announced that Carl Meyer, M.D., The Iowa Clinic in West Des Moines, IA, ... Dr. Meyer has achieved a high level of training and experience with the ...
(Date:7/10/2020)... (PRWEB) , ... July 10, 2020 , ... ... Release 3.0 featuring our Business Partner Vetting (BPV) Portal . Expresso® ... and upload requested documents. No more manually mailing, tracking, and performing other administrative ...
(Date:7/7/2020)... ... July 07, 2020 , ... Dr. Louis M. ... new way to improve their scalp health. It is now possible to receive Keravive ... treatment process to his practice, Dr. DeJoseph is able to provide clients with the ...
(Date:7/7/2020)... ... July 07, 2020 , ... ... two head design to efficiently sanitize large surfaces is now available in Mexico ... to support sales in that region. , In this era of worldwide pandemic, ...
Breaking Medicine News(10 mins):
(Date:7/10/2020)... Calif. (PRWEB) , ... July ... ... Review , the leading review of business and technology for the pharmaceutical ... the development and manufacturing of the highest quality pharmaceutical products. QC ...
(Date:7/7/2020)... ... July 07, 2020 , ... With projects ranging from ... the 33 nonprofits who received the latest ISA Foundation grants will ... the foundation awarded grants totaling $838,527 to the U.S.-based 501(c)(3) nonprofit organizations. ...
(Date:7/4/2020)... ... 03, 2020 , ... By Heidi Jean Doerfert , During this unprecedented time ... cover, Assuaged, Inc. is going full speed ahead. Founders Cynthia and Thane ... to get their feet wet in marketing, social media content, research, data analysis and ...
Breaking Medicine Technology:
Cached News: