HOME >> MEDICINE >> NEWS
Nerve Cells Live Long And Talkative Lives In Sculpted Colonies On Silicon Chips

At a Texas meeting May 14, USC researcher Roberta Diaz Brinton will discuss her research and the hopes she has for the colonies of rat nerve cells she has cultured -- and even sculptured -- on silicon semiconductor substrate. She envisions that hybrid brain-electronic systems may soon serve to elucidate the process by which brains perform complex functions, including specific pattern recognition. Such systems may also form part of a new generation of chemical detectors.

Brinton, an associate professor of molecular pharmacology in the School of Pharmacy, also plans to use her wired colonies of cells for studies in her specialty, the study of the effects on the brain of the hormone estrogen and allied substances.

Finally and most ambitiously, Brinton and co-workers from the USC School of Engineering's department of biomedical engineering hope to someday be able to implant similar chips into living brains as both experimental instruments and eventually as prostheses.

The cells come from a part of the brain called the hippocampus, which is associated with short term memory. Brinton dissociates the cells from their intricate network of interconnections with each other, and then places them as individual cells on a specially prepared silicon testbed studded with a matrix of electrodes.

The dissociated cells, approximately 80,000 of them, affix themselves to the testbed and grow, sending out processes and reforming synaptic contacts with each other. They can live on the chips for extended periods -- as long as months, according to Brinton.

Brinton's lab is one of only a very few in the world able to culture and study such nerve cell colonies.

During the course of the nearly two years Brinton has been working with the technique of culturing on silicon, she and her co-worker, graduate student Walid Sassou have learned to make and use masks made by traditional photo-resist processes to "sculpt" the colonies into desired shapes by placement of the s
'"/>

Contact: Eric Mankin
mankin@usc.edu
213-740-9344
University of Southern California
13-May-1999


Page: 1 2 3

Related medicine news :

1. Nerve damage from alcoholism reversed after liver transplantation
2. Nerve navigation findings prompt new direction for spinal cord research
3. Vagus Nerve Stimulation Therapy (TM) more effective in epilepsy patients when used earlier
4. Cut Nerve Fibers Are Repaired In An Animal Model of Spinal Cord Injury; May Help Repair Nerve Damage In Humans
5. Percutaneous Electrical Nerve Stimulation May Offer Dramatic Short-Term Relief For Chronic Back Pain
6. Hunter College Biologist Marie Filbin Identifies Mechanism That Blocks All Inhibitors Of Nerve Regeneration; Breakthrough Reported In Neuron Magazine
7. Electrical Nerve Stimulation May Help Reduce Chronic Pain In Cancer Patients, Say UT Southwestern Researchers
8. Nerve Agent Sensor A Million Times More Sensitive
9. Study Shows Potential For Quelling AIDS Nerve Pain
10. Surprise! Cells have second source of phosphate
11. Cells from fat tissue turned into functional nerve cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/11/2019)... ... November 11, 2019 , ... ... shipment of two (2) Gruenberg Depyrogenation Sterilizers to the Pharmaceutical Industry. ... have maximum temperature ratings of 280°C with work chamber dimensions of 36” W ...
(Date:11/11/2019)... ... ... PracticeLink Live! Atlanta Physician Career Fair will take place Thursday, November 14, 2019, at ... 8:00 p.m. A free, optional seminar for job-seeking physicians, residents and fellows, When to ... career fair and seminar are open to residents and fellows, as well as practicing ...
(Date:11/7/2019)... (PRWEB) , ... November 06, 2019 , ... Atlantic Ultraviolet ... the flu is to get the flu shot. Since the flu season starts in ... Clinic in early Fall, where their employees can simply sign-up and get their shot. ...
(Date:11/7/2019)... ... ... excited to announce that the Medical Spa Show 2020 exhibit hall floor has been sold ... JD. “Every year, we have expanded the size of the floor to accommodate all of ... best options for attendees, and this year is no exception. The exhibit hall floor is ...
(Date:11/6/2019)... ... 06, 2019 , ... Founder of the Trivedi Effect®, Guruji ... of their understanding, as well as, to illuminate the path of awareness and ... and fortune. , The next Trivedi Effect® Online Workshop is scheduled at ...
Breaking Medicine News(10 mins):
(Date:11/6/2019)... , ... November 06, 2019 , ... ... product, NeoCyteXO. The exosome product offers significant advantages to all others on the ... most current pricing being received. Call (888) 568-6909 for more information and ordering. ...
(Date:11/5/2019)... ... November 05, 2019 , ... Modern Living Living with kathy ireland® ... Holistic Medicine Heidi Reaganass and Head of Channel Partnerships and Media Relations Monty Bernardi ... , Goli Nutrition is a nutrition company. Their goal is to help people ...
(Date:11/4/2019)... ... ... An estimated 10 million Medicare beneficiaries who are covered by a Medigap policy and ... Medicare premiums, according to a national survey conducted by The Senior Citizens League ... in retirement, yet the annual cost-of-living adjustment (COLA) is adjusted using an index that ...
Breaking Medicine Technology:
Cached News: