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New Canadian study demonstrates clear survival benefit of treatment in trials and at large centres

entres with larger caseloads is partly explained by the fact that these centres usually also participate in research and vice versa.

"But what is clear is that, since we adjusted for key prognostic factors among the women, the explanation for the better survival was not due to any baseline characteristics of the patients or to them being selectively chosen to participate in clinical trials."

She said that the specific strength of the analysis examining participation in clinical trials was that it was population-based and assessed all the breast cancer trials available to women with node-negative breast cancer in Quebec during the study period and had not confined itself to one specific trial protocol or a few.

"The lessons from our findings are that women derive substantial benefit from participating in clinical trials and that their gain in survival is at least as great as compliance with current standards of care. It is also clear that the better outcome for patients treated in larger centres is partly explained by these centres' participation in research. Treatment centres should be encouraged to become affiliated to the networks of collaborating institutions so that more patients can share in these benefits."


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Contact: Margaret Willson
m.willson@mwcommunications.org.uk
49-403-569-3625
Federation of European Cancer Societies
19-Mar-2004


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