HOME >> MEDICINE >> NEWS
New Chemicals Could Lead To First Bone Growth Pill

ANAHEIM, Calif., March 21 -- New chemicals that, if successful, could become the first osteoporosis treatment to stimulate new bone growth -- rather than merely retard bone loss -- were described here today at a national meeting of the American Chemical Society, the world's largest scientific society. Researchers from the Seattle biotechnology company ZymoGenetics Incorporated said their new compounds are showing positive results in animals and, unlike other bone-growth candidates, can be put in a pill.

In humans, bone undergoes continuous remodeling, with cells called osteoclasts "eating up"old bone as osteoblast cells replace it with new bone. Osteoporosis, which affects some 15-20 million Americans, is caused by increased bone breakdown without new bone formation. The result is a loss of bone mass and increased susceptibility to fractures, most commonly in those age 45 and older. The cost of treatments associated with osteoporosis in the U.S. has been estimated at $3.8 billion annually.

Current treatments, including estrogens, all act to decrease bone loss. They can't do anything about bone that is already gone and, therefore, are not helpful to everyone. "Our new bone forming agents may have better and more widespread utility for treatment of osteoporosis," said ZymoGenetics senior scientist Nand Baindur, Ph.D.

There are currently no drugs available to help grow bone. Researchers have tried giving patients proteins that the body naturally uses to stimulate osteoblasts, such as parathyroid hormone and bone morphogenic proteins (BMPs). But, according to Dr. Baindur, those clinical trials have been mostly unsuccessful or inconclusive. Furthermore, he explains that proteins are big molecules which can usually be given only by injection and don't hold up well in the body. Even if such treatments worked, he adds, the proteins are generally difficult to formulate and manufacture, tending to eventually make them expensive.

Instead of usin
'"/>

Contact: Charmayne Marsh
y_marsh@acs.org
202-872-4445
American Chemical Society
22-Mar-1999


Page: 1 2

Related medicine news :

1. Chemicals in tattoo inks need closer scrutiny
2. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
3. Chemicals found in cherries may help fight diabetes
4. MIT Microchip Releases Chemicals On Demand
5. Could skin cells become brain cells?
6. Could autoantibodies predict future disease in healthy people?
7. Could this be the end for injections?
8. Could you suffer from psychosis? The nose knows
9. Could a mandated food additive aimed at better fetal development be a risk for seniors?
10. Could an aspirin a day help keep prostate cancer away? Possibly
11. Drug blocks opioid side effects: Could improve palliative care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/8/2020)... ... ... Quality Health Care Concierge was founded by Michelle Kavall, RN ... comfortable and preferred lifestyle with their Companion Care services in the Boca Raton and ... a leader in the healthcare field for over a decade. Thanks to her impressive ...
(Date:1/7/2020)... ... 2020 , ... Red Oak Recovery® is excited to announce ... Oak Recovery effective immediately. Ian began working in the behavioral healthcare industry ... centers for adolescents. In this capacity, Ian worked with clients who had a ...
(Date:1/7/2020)... ... January 06, 2020 , ... MemoryCare.com , a comprehensive ... Best Memory Care Facilities in Lakeland, Florida. The guide identifies 6 memory care ... According to the Alzheimer’s Association , 5.6 million people age 65 and ...
(Date:1/5/2020)... ... 2020 , ... NJ Top Dentist, Dr. Irvin B. Sherman has been reviewed ... infants, children, teens and the special needs patient. The practice is located in Avon ... health. , Dr. Sherman and his practice will be addressing issues that mothers are ...
(Date:1/2/2020)... Calif. (PRWEB) , ... January 02, 2020 , ... NEA ... new Jeep® Compass* from California Casualty . , Educators lead extremely busy ... they are behind the wheel. From smartphones to navigation devices, new technology is a ...
Breaking Medicine News(10 mins):
(Date:1/10/2020)... ... January 10, 2020 , ... ... 2020 in Las Vegas and showcasing a system of connected performance apparel ... athletes to their bodies, their training partners and coaches. Connected fitness represents just ...
(Date:1/8/2020)... ... January 08, 2020 , ... ... able to accept Medicare for medication-assisted treatment services at their Opioid Treatment ... naltrexone, all FDA-approved medications, as well as counseling, began on January 1st. ...
(Date:1/7/2020)... ... 07, 2020 , ... Valencell today announced the ... in hearables and wearables. Valencell will provide the BP sensor system as a ... products. Embedded in an earbud reference design, the technology has demonstrated BP cuff-like ...
Breaking Medicine Technology:
Cached News: