New Drug For Recurrent Brain Tumors In Tests At UNC

l's ability to grow."

The drug is administered intravenously. Initially, patients will get a dose every day for four days and then once a week for up to a year. Patients with a good response can continue on the medicine beyond that, as long as they're doing well, Ewend says. Adverse effects from the drug include headache, confusion and sleepiness. Some test subjects have developed gastrointestinal upset, but Ewend notes that most people tolerate SU101 very well.

The second study is a phase II clinical trial, which like the GBM study, also is sponsored by Sugen. This preliminary trial will test the effectiveness of SU101 against anaplastic astrocytoma, a slightly lower grade malignancy than GBM.

"The dose has been established and this is an open trial. All enrolled will get the drug, so we can look for evidence of a positive effect against the tumor," Ewend says.

According to the neurosurgeon, anaplastic astrocytoma is very similar to GBM. "Patients may be eight to 10 years younger with a median survival of a few years rather than one year. But it's a high-grade tumor, and people with anaplastic astrocytoma can develop glioblastoma. So aggressive therapy is still required."

Over 20 centers nationally are involved in the GBM phase III trial and more than 15 are in the anaplastic astrocytoma phase II trial. UNC-CH is the only center in North Carolina involved in these SU101 brain tumor studies.

Persons interested in enrolling in either trial should contact Dr. Ewend at 919-966-1374.


Contact: Lynn Wooten
University of North Carolina School of Medicine

Page: 1 2

Related medicine news :

1. Brain activity prior to treatment flags vulnerability to antidepressant side effects
2. Brain imaging study may hold clues to onset of schizophrenia in people at high risk
3. Brain imaging reveals secrets of love, fear and betrayal
4. Brain imaging studies investigate pain reduction by hypnosis
5. Brain tumor with dismal prognosis in infants can be cured in older children
6. Brain-scanning technologies need standards, according to Stanford researcher
7. Brain activity of men and women during hostile or impulsive acts differs less on nicotine
8. Brain synapse formation linked to proteins, Stanford study finds
9. Brain tumor treatment can vary greatly, according to new JAMA study
10. Brain region identified that controls collecting behavior
11. Brain imaging reveals new language circuits

Post Your Comments:

(Date:10/8/2019)... ... ... What unique insights can three former Surgeons General of the United States ... That question will be answered at ICAA 2019: Shaping the Future of Wellness, this ... take place October 10-12, 2019, at the Gaylord Palms Resort and Convention Center in ...
(Date:10/8/2019)... WASHINGTON (PRWEB) , ... October 08, 2019 , ... ... development and support services for the Department of Veterans Affairs Community Care Referrals ... continue its implementation of the VA’s Health Share Referral Manager (HSRM), an enterprise-wide ...
(Date:10/8/2019)... ... 08, 2019 , ... Over the past three decades, Buffalo Wings & Rings ... restaurant category by providing a higher-quality product and experience than the competition. Now, the ... a "RAISE A MUG FOR THE CAUSE" campaign in support of Breast Cancer Awareness ...
(Date:10/8/2019)... ... October 08, 2019 , ... The University of California ... Health Awards 1st Round (Top Ten) Finalist in its Best Cardiovascular Digital Diagnostic ... that promote faster, better, more cost-effective healthcare by improving outcomes such as shorter ...
(Date:10/8/2019)... ... October 08, 2019 , ... Fewer ... billion per year, are reproducible. Rigor in bioanalytical method validation is emerging in ... estimates, more than half of the time) and senior scientists add the management ...
Breaking Medicine News(10 mins):
(Date:10/8/2019)... ... 08, 2019 , ... Help.org, a trusted online resource for individuals who struggle ... Massachusetts for 2019. The informational guide recognizes the top 17 rehab facilities based on ... studies , drug overdose is the leading cause of death among people under age ...
(Date:10/8/2019)... ... October 08, 2019 , ... Respected ... dental implant seminar to enhance his skill and knowledge of dental implant diagnosis, ... Continuum™ is a four-part series of classes that combines in-depth lectures with hands-on ...
(Date:10/8/2019)... (PRWEB) , ... October 08, 2019 , ... Villa Healthcare, ... contest asking why they chose to work at Villa and what their work means ... CEO Mark Berger and CFO Steve Nagel prepared the giant checks. Anticipation was ...
Breaking Medicine Technology:
Cached News: