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New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report

man's bones and cholestoral levels, yet does not mimic estrogen's adverse effects on her breasts and uterus.

Estrogen acts by binding to structures called receptors in various target tissue cells, which then stimulate different responses. The hormone can cause tissue growth in a woman's breasts and uterine lining, and over time, may increase her risk of breast or endometrial cancer.

At the same time, however, estrogen has been proven to significantly reduce a woman's risk of osteoporosis and may reduce her risk of heart disease. Raloxifene was approved for the prevention of osteoporosis by the Food and Drug Administration in December 1997. It is marketed as Vista by Eli Lilly and Co., the sponsors of the clinical trials of the treatment as a method of preventing breast cancer.

Note To The Media:

To interview Steven Cummings, M.D., please contact Abby Sinnott in UCSF news services at (415) 885-7277.


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Contact: Abby Sinnott
sinnott@itsa.ucsf.edu
(415) 885-7277
University of California - San Francisco
18-May-1998


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