HOME >> MEDICINE >> NEWS
New Technique Induces Growth Across Spinal Cord Injury

Using a totally new approach, researchers at the Massachusetts General Hospital (MGH) have for the first time induced the growth of severed adult mammalian spinal cord fibers across the site of the injury. The animal study appearing in the May issue of Neuron is the first to report repairing such an injury without the use of implanted cells or tissues to bridge the severed fibers. In addition, the findings call into question current assumptions about barriers to spinal cord regeneration.

"We have actually tricked nerve cells into growing beyond the area of a spinal cord injury by switching them into an actively growing state," says Clifford Woolf, M.D., Ph.D., of the Neural Plasticity Research Group in the MGH Department of Anesthesia and Critical Care, who led the study. "While the particular approach we used cannot be applied in humans, it points us in a promising new direction. The question is no longer whether spinal cord regeneration is possible but how it will be achieved."

It has been known for years that severed nerve fibers in the adult spinal cord cannot regenerate. However, damaged peripheral nerves - those in the extremities - can heal themselves. What has intrigued and frustrated researchers is the fact that the fibers making up one sensory system in the spinal cord come from the same cells as do the fibers in peripheral nerves. These sensory nerve cells or neurons have two long processes, called axons, that extend from the main cell body located next to the spinal cord. One axon, the central branch, joins the spinal cord and travels to the brain; the other, the peripheral branch, travels out to the extremities. If the peripheral branch of these cells is injured, it regenerates; if the central branch is injured, it does not.

Because two branches of the same cell exhibit totally different healing capacities, most researchers thought the difference must lie in the environments surrounding the branches, which are very different. Pr
'"/>

Contact: Susan McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
28-May-1999


Page: 1 2 3

Related medicine news :

1. Techniques for making Barbie dolls can improve health care
2. Technique reduces time spent on radiation doses
3. Less Toxic Bone Marrow Transplant Technique May Have More Powerful Anti-Cancer Effect
4. Nonintrusive Imaging Technique Useful For Identifying Language Regions In Kids Brains
5. Non-Invasive Techniques To Visualize Heart Disease Confirm Importance Of Pre-Menopausal Risk Factors, Find U. Of Pgh. Researchers
6. Combined Use Of New, Non-Invasive Screening Techniques In First Trimester May Yield Earlier Evidence Of Fetal Birth Defects
7. University Of Kentucky One Of First To Use New Technique To Treat Atrial Flutter
8. New Ultrasound Technique Is Alternative To Cerebral Angiography
9. Substance Discovered That Induces Hair Follicle Formation In The Mature Skin Cells Of Mice
10. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
11. Growth factor grows stem cells that help heal hearts

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/2/2020)... ... June 02, 2020 , ... Join Nagy Habib, Professor of ... R&D, HalioDx in a live webinar on Monday, June ... has proved to be immensely informative in the context of clinical trials. Multiplex ...
(Date:6/2/2020)... ... June 02, 2020 , ... ... solutions for drugs, biologics, cell and gene therapies, and consumer health products, today ... Mr. Lickfold succeeds John McGill, who, following a period of transition, plans to ...
(Date:5/30/2020)... , ... May 29, 2020 , ... ... Florida and South Carolina conducting Phase I-IV trials, commemorated May, Mental Health Awareness ... that make medical advances possible. , Efforts include their #StayConnected video series ...
(Date:5/30/2020)... PALO ALTO, Calif. (PRWEB) , ... May 30, ... ... helping them with advanced technology and virtual solutions that can meet the needs ... post-pandemic world. , HashCash’s healthcare solutions abide by the necessary compliances ...
(Date:5/28/2020)... ... May 28, 2020 , ... Today the National ... protection. Donors can now be reimbursed for lost wages and travel/lodging costs for ... Donor Shield protections include lost wage reimbursement for donation, travel & lodging reimbursement ...
Breaking Medicine News(10 mins):
(Date:6/3/2020)... ... 2020 , ... Ridgecrest Healthcare, a skilled nursing and ... ALFM-BC, as its new Executive Directory and Administrator. Villafranca assumes all the roles, ... career in healthcare in 1994 and has held various positions in senior living ...
(Date:6/3/2020)... ... 2020 , ... GrandPad , creator of the first ... capabilities to its mobile device and telehealth platform to support virtual care and ... an increasing number of home health agencies and other healthcare companies are turning ...
(Date:6/2/2020)... ... June 02, 2020 , ... Adoptive cell therapies ... watershed FDA approvals of two Chimeric Antigen Receptor T-Cell (CAR-T) therapies in 2017. ... T-cell receptor T-cells (TCR-Ts), Natural Killer (NKs) cells and Dendritic Cells (DCs). , ...
Breaking Medicine Technology:
Cached News: