HOME >> MEDICINE >> NEWS
New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease

Medical researchers have found that adding a simple molecular chain to a standard medication for lung disease creates a new therapy that shows promise for difficult-to-treat cases resulting from acute lung injury. Scientists from the University of California San Francisco led the team, which also included researchers from the University of Rochester and the Karolinska Institute in Sweden.

The standard medication is artificial surfactant, a detergent-like liquid that is administered directly into the lungs. Studies in animal models showed the extra molecular chain--made of a compound bio-compatible with mammalian tissue--appears to act as a protective barrier, allowing normal function of a key substance that lines the air spaces in the lungs. This substance is natural surfactant, a lung secretion that is vital to normal pulmonary function because it keeps the lungs from collapsing after each breath.

Reporting today (May 4) at the annual meeting of the Pediatric Academic Societies in San Francisco, principal investigator H. William Taeusch, MD, of UCSF, said rats with diseased lungs treated with the enhanced medication had improved oxygen levels in the blood, an indication that lung function is not compromised.

"The study findings are dramatic, and we are excited at the potential of someday successfully treating infants and adults who have lung problems that don't respond well to current treatment. We have been frustrated with the poor outcome in these groups, and our results suggest that we could be on the road to a much-improved therapy," said Taeusch, who is a UCSF professor of pediatrics and chief of the Department of Pediatrics at the UCSF-affiliated San Francisco General Hospital Medical Center.

Some 5,000-10,000 infants and 100,000 adults in the U.S. suffer from acute lung injury every year. Their disease differs from premature babies who at birth suffer from respiratory distress syndrome--also known as hyaline membrane disease-
'"/>

Contact: Corinna Kaarlela
ckaarlela@pubaff.ucsf.edu
415-476-3804
University of California - San Francisco
4-May-1999


Page: 1 2 3

Related medicine news :

1. Artificial liver trials show progress, as transplant candidates wait
2. Artificial organs
3. Artificial liver moves toward commercialization
4. Trial Begins For First Artificial Liver Device Using Human Cells
5. Randomized Contolled Study Shows Neostigmine Is An Effective Treatment For Acute Colonic Pseudo-Obstruction
6. Research Shows That Noncompliance Is Responsible For Half The Cases Of Nonresponse To Antihypertensive Drug Treatment
7. Anal Cancer Screening For HIV-Positive Gay And Bisexual Men Would Save Lives And Be Cost Effective, New Study Shows
8. Anti-Depressant Drug Shows Promise As Weight-Loss Treatment
9. UCSF Study Shows That An Herbal Therapy Reduces PSA Levels By Half In Men With Advanced Prostate Cancer
10. Evidence Shows Drug-Psychotherapy Combo Effective For Chronic Depression
11. Research Shows Religion Plays A Major Role In Health, Longevity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... ... February 13, 2019 , ... Intalere will hold its annual ... Elevate 2019 at the Gaylord Rockies Resort & Convention Center, Denver, Colo. The ... driving improved quality of patient care, reduced costs and enhanced revenue opportunities in ...
(Date:2/13/2019)... ... February 13, 2019 , ... That wintry landscape outside ... white stuff from walkways and driveways. Then, the snow can quickly become a pain ... muscle you use to remove it,” says noted orthopaedic surgeon Kevin D. Plancher, ...
(Date:2/13/2019)... , ... February 13, 2019 , ... Infertility is an issue for 1 in 6 ... A startling 2017 study outlining the sharp decline in male sperm count over the last ... , garnering worldwide attention and causing panic that we are in the midst of a ...
(Date:2/13/2019)... ... February 13, 2019 , ... Dr. Jig Patel ... Dr. Muizz Merchant, an exceptionally talented and knowledgeable dentist from St. Louis, ... modern dental techniques, such as CEREC same-day dentistry, root canals and emergency treatment. Dr. ...
(Date:2/13/2019)... ... February 13, 2019 , ... California ... celebrated February 8 at the NEA Foundation’s 2019 Salute to Excellence in Education ... The inspirational evening featured 46 instructors who were chosen by their peers for ...
Breaking Medicine News(10 mins):
(Date:2/14/2019)... ... February 14, 2019 , ... Neptune Society’s new location in Fort Worth, TX, ... and ribbon-cutting ceremony on Thursday, February 21, 2019. Members of the community can visit ... Guests may RSVP by calling the office directly at (817) 838-5100. , The ribbon-cutting ...
(Date:2/13/2019)... , ... February 13, 2019 , ... Swinerton is closing ... 275,000 square-foot, class A office building, designed by Little Diversified Architectural Consulting out of ... than 1000 associates consolidated from Adventist Health’s six current locations in Roseville into a ...
(Date:2/13/2019)... ... February 13, 2019 , ... NCPDP announced today ... keynote speech on Wednesday, May 8, at its 2019 Annual Technology & Business ... Kierland Resort & Spa in Scottsdale, Arizona, and is expected to draw more ...
Breaking Medicine Technology:
Cached News: