HOME >> MEDICINE >> NEWS
New centers boost muscular dystrophy research

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Child Health and Human Development (NICHD), parts of the National Institutes of Health (NIH), have funded three new cooperative research centers for the muscular dystrophies (MD), a group of genetic diseases that result in muscle weakness and wasting. The three institutes will fund the centers at up to $1 million in direct costs per center per year for 5 years. The NIH expects to fund up to two additional centers in future years.

The centers, principal investigators, funding agencies and planned research include:

  • The University of Pittsburgh, Joseph C. Glorioso, Ph.D. (NIAMS). Scientists here will study gene and stem cell therapies to treat muscle disease, in particular Duchenne muscular dystrophy. One project will attempt to deliver and engraft muscle stem cells into diseased heart tissue without causing an immune response. Researchers will also use herpesvirus vectors in functional genomics studies to discover and characterize factors that guide stem cell maturation into muscle. In collaboration with scientists at the University of Missouri and Ohio State University, adeno-associated viral vectors will be exploited in preclinical studies in a dog MD model seeking the most effective ways to deliver gene therapy. Clinical disease outcomes will be carefully defined in patients with Duchenne and limb-girdle muscular dystrophies for the preparation of phase I gene therapy safety trials.
  • The University of Washington, Seattle, Jeffrey S. Chamberlain, Ph.D. (NICHD). This center will conduct studies to develop new gene therapies for Duchenne muscular dystrophy. Researchers have already achieved some success with viral vectors in delivering genes to mouse muscle. Investigators will use animal models to study several aspects of gene therapy to guid
    '"/>


Contact: Ray Fleming
flemingr@mail.nih.gov
301-496-8190
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
14-Oct-2003


Page: 1 2 3

Related medicine news :

1. Advertising by academic medical centers may risk eroding public trust, says study
2. Dedicated hospital stroke centers improve quality of acute care
3. Orqis receives FDA approval to expand clinical trial of Cancion CRS therapy to 40 centers
4. NIA establishes new demography centers to enhance knowledge about older americans
5. Study compares overnight dialysis to treatment in centers
6. Florida study shows surgical mishaps more likely in physician offices than surgery centers
7. HHS announces new regional centers for biodefense research
8. Assessment finds gaps in access to nations trauma centers
9. National Census finds most US counties dont have enough adult day centers
10. New centers to research, reduce asthma disparities
11. UNC among 10 U.S. medical centers tapped to study living donor liver transplants

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... The ... the focus of Fall 2020 Virtual Conference, a two-day virtual event for radiology ... Imaging & Beyond" is the follow-up to AuntMinnie.com's successful virtual event in spring ...
(Date:9/2/2020)... ... September 02, 2020 , ... RAM Technologies, ... administering Medicare Advantage and Special Needs plans, is proud to support the 2020 ... Plans (AHIP). RAM is supporting the event as a sponsor and exhibitor and ...
(Date:9/1/2020)... ... 2020 , ... As fall and winter swiftly approach and many businesses cut ... taken this time to expand and grow into a full-fledged natural health clinic over ... will be relaunching its brand new website, expanding its services menu and has recruited ...
(Date:8/31/2020)... ... ... found out your dear friend has cancer? , It’s hard to hear your doctor say ... diagnosis. Once the shock wears off, the questions and fears can be overwhelming. , How ... to help? Words are failing me. I’m scared. I want to DO something. , We’ve ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University ... career-relevant, and affordable online education – is proud to announce its new master’s ... first of its kind in the nation, the 60-credit hour program is designed ...
Breaking Medicine News(10 mins):
(Date:9/3/2020)... (PRWEB) , ... September 03, 2020 , ... Using Analysis ... FDAnews Webinar, Thursday, Sept. 17, 2020, 1:30 p.m.-3:00 p.m. EDT, https://www.fdanews.com/anova , ... expert statistician? , While one can’t become one in 90 minutes, one can ...
(Date:9/2/2020)... , ... September 02, 2020 , ... U.S. Dermatology ... Lee . Dr. Lee will work at Bethesda Dermatopathology Lab. , ... B.A. from the University of California, Berkley. He went on to receive his M.D. ...
(Date:9/1/2020)... ... ... While coronavirus cases continue to increase across the country, blood drives are ... Because about 80% of blood donations are made at drives hosted by these groups, ... hosts to ensure blood products are readily available for patients. , Those interested ...
Breaking Medicine Technology:
Cached News: