HOME >> MEDICINE >> NEWS
New data support the efficacy and safety of the novel oral anticoagulant Exanta

(Mlndal, Sweden, 10 July 2001) The presentation of a wide range of data at the 18th International Society on Thrombosis and Haemostasis meeting (ISTH) in Paris this week, provided new evidence to support the efficacy and safety of Exanta, which is set to be the first new oral anticoagulant since warfarin was introduced over 50 years ago.

Exanta, an oral direct thrombin inhibitor, is currently under investigation in an extensive phase III clinical trials programme in a number of key therapeutic areas. The programme, which involves more than 15,000 patients in 30 countries, includes European and US phase III studies in the prevention of blood clot formation in the leg veins of patients undergoing orthopaedic surgery, presented at the ISTH. These blood clots in leg veins, or deep vein thrombosis (DVT), can dislodge and travel to the lung causing pulmonary embolism (PE). DVT and PE together are known as venous thromboembolism (VTE).

Dr Ian Watts, Global Product Director, said: "Over 20 abstracts were selected for oral and poster presentation at the ISTH meeting, including the phase III results from US and European trials of VTE prophylaxis in orthopaedic surgery. These data show that Exanta has efficacy and tolerability at least comparable to that of warfarin or a low molecular weight heparin compound, the standard anticoagulants in the US and Europe respectively."

The European phase III trial, one of the largest ever trials of VTE prophylaxis in orthopaedic surgery, included 2788 patients undergoing total hip or total knee replacement surgery, in centres across Europe. The study, which compared the efficacy and safety of Exanta to the low molecular weight heparin, enoxaparin showed it to be effective and well tolerated for VTE prevention, with efficacy comparable to that of enoxaparin. The earlier phase II trial also showed Exanta to be comparable to another low molecular weight heparin, dalteparin.

The US phase III trial,
'"/>

Contact: Rina Amin
rina.amin@ketchum.com
44-20-7611-3513
Ketchum
10-Jul-2001


Page: 1 2 3

Related medicine news :

1. Americans support most uses of reproductive genetic testing, report on US attitudes reveals
2. Northwestern Memorial Hospital receives $10 million commitment to support preeminent heart program
3. Emergency department study supports giving dehydrated children fluids by mouth
4. Early supported discharge services can reduce long term dependency for stroke patients
5. Care of rural stroke patients improves with telephone support
6. Review supports link between HRT and stroke
7. Chamomile tea: New evidence supports health benefits
8. Psychological support helps adolescents with chronic fatigue syndrome
9. Social supports lessen effects of maltreatment on children vulnerable to depression
10. Immigration, lack of partner support are postpartum
11. Study supports the use of mechanical assistance

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/9/2019)... ... December 09, 2019 , ... ... solutions that help food and manufacturing companies engage with their workforces to ... turnkey solution helps manufacturers build a cohesive culture that is designed to ...
(Date:12/8/2019)... , ... December 07, 2019 , ... More than 85 ... a recent report from the American Academy of Dermatology, indicating this problem is more ... upward trend during the years to come. These dermatological conditions vary in type and ...
(Date:12/8/2019)... SEATTLE (PRWEB) , ... December 08, 2019 , ... ... higher education planning, has announced the Top 52 Best Homeland Security Degree Programs ... accredited colleges and universities in the nation. Each program is evaluated based on ...
(Date:12/6/2019)... ... 2019 , ... Connecticut is home to a growing healthcare ... On December 12th, Hartford Business Journal will recognize eight individuals and organizations who ... the Hartford Marriott. , “We are fortunate to have so many great providers ...
(Date:12/6/2019)... , ... December 06, 2019 , ... Lasair Aesthetic Health Sponsors Toys for Tots to ... of Botox to Patients Who Bring in Toys During the Holidays , Lasair Aesthetic Health ... now until Christmas, patients who bring in a toy or toys worth more than 25-dollars, ...
Breaking Medicine News(10 mins):
(Date:12/5/2019)... ... December 05, 2019 , ... Intelligent.com, a ... Top 27 Respiratory Therapy Degree Programs for 2020. The comprehensive research guide is ... Each program is evaluated based on curriculum quality, graduation rate, reputation, and post-graduate ...
(Date:12/5/2019)... ... December 05, 2019 , ... nView, a leading behavioral health ... role of Chief Product Officer. As the company expands its portfolio of software ... behavioral health market into nView’s product and company growth strategy. Rosenbaum will report ...
(Date:12/4/2019)... LAKE FOREST, Calif. (PRWEB) , ... December 04, ... ... medical technology company providing healthcare professionals with minimally invasive technologies to treat chronic ... 100,000 procedures performed with the Tenex Health TX® technology. , Dr. ...
Breaking Medicine Technology:
Cached News: