HOME >> MEDICINE >> NEWS
New discovery may revolutionize treatment for pain related to surgery, illness and injury

For those suffering from pain, scientists from UCLA and the University of Cambridge, United Kingdom, report a revolutionary advance in pain medicine that promises to deliver painkillers directly to the affected area of the body, in smaller doses and with fewer side effects.

The researchers report the first clinically suitable method using nerves as a means of safely delivering high doses of painkillers to achieve a therapeutic effect. They announced their research findings at the Society for Neuroscience conference on Nov. 8 in New Orleans, La.

UCLA neurosurgeon Aaron Filler and his colleagues used a method called "axonal transport" to deliver a pain drug to the spinal ganglia and spinal cord, using nerves as a conduit, in an animal model.

Axonal transport works like a "conveyor-belt" process, delivering pain-relieving medication to remote sensory endings in the tissues of the body. In axonal transport, the cell moves molecules from one end of the cell to the other, thus supporting their ability to communicate with other neurons. A single neuron may be more than two feet long.

Although axonal transport has played a role in thousands of research studies in the past, this is the first-ever report of a positive clinical effect with a potential human medication. The new technology uses a novel molecular structure to achieve clinically effective dosing in targeted groups of nerves, Filler said.

This work marks an important advance, because drug treatment of nervous-system disorders is often hindered and sometimes precluded when the precise site of the injury or disease cannot be reached with adequate levels of pain medicine without causing unwanted side effects. Delivery of painkillers directly to selected target sites can avoid undesired toxicity, as well as inappropriate side effects in non-target neural tissue.

Filler says that with this new method of delivering pain medication, one shot administered during surgery coul
'"/>

Contact: Roxanne Yamaguchi Moster
roxannem@support.ucla.edu
310-794-2264
University of California - Los Angeles
7-Nov-2000


Page: 1 2 3

Related medicine news :

1. TB Alliance announces new drug discovery program with GlaxoSmithKline
2. Mayo Clinic discovery on nature of rheumatoid arthritis lung disease may offer patients therapy
3. Canadian researchers important discovery in HIV research
4. Long-sought key to hearing may be found in protein discovery
5. Novel vitamin discovery offers clues for cancer chemotherapy and lipid disorders
6. Lupus discovery may pave way to better-designed COX-2 inhibitors
7. New discovery may lead to therapy for incurable blood cancer
8. DuPont-led scientists unveil key nanotechnology discovery with use of DNA
9. Canadian discovery promises treatment for HIV dementia
10. Ann Arbor chemist wins national award for drug discovery
11. Zebrafish: Drug discovery of a different stripe holds promise in COX research

Post Your Comments:
(Date:10/20/2014)... Houston plastic surgeon Dr. Christopher Patronella ... innovative True Form Tummy Tuck® method as ... at The University of Texas Medical Branch in ... medical student. Patronella, who is a founding partner of ... in Texas, The Aesthetic Center for Plastic Surgery ...
(Date:10/19/2014)... The leading review website, Top10BestSEOHosting.com, has recently announced ... the best Dedicated Server Hosting suppliers. Their websites ... buy high quality hosting and save money at ... Top10BestSEOHosting.com says, “We believe that iPage and GreenGeeks ... lot of the global clients enjoy using their ...
(Date:10/19/2014)... Texas (PRWEB) October 20, 2014 ... development for Partial Seizure, complete with comparative analysis ... mechanism of action (MoA), route of administration (RoA) ... featured news and press releases. It also reviews ... Partial Seizure and special features on late-stage and ...
(Date:10/19/2014)... October 20, 2014 Recently, Fancyflyingfox.com, an ... occasion clothes, has announced its latest designs of 2014 ... all the new elegant outfits are offered with big ... an order before October 30 can enjoy this special ... great marketing strategies, it has become one of the ...
(Date:10/19/2014)... Woodbury, NY (PRWEB) October 20, 2014 Stephen ... NY, has been nominated for the 10th consecutive year as ... this year Dr. Greenberg was also been nominated as the ... Spa was also nominated as best Day Spa and best ... place until December 14th and readers can vote for the ...
Breaking Medicine News(10 mins):Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 4Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2Health News:Dr. Stephen T. Greenberg – Nominated for the 10th Consecutive Year for One of Long Island’s Best Cosmetic Surgeons for 2015 by the Long Island Press 2
(Date:10/17/2014)... 17, 2014 The following is being ... The Green Park Collaborative (GPC) will ... private payers, medical device and pharmaceutical companies, as ... January 12, 2015 at its first ever workshop ... loss treatments.  Participants will discuss study designs to ...
(Date:10/17/2014)... Inc ., reported on results of 59 glaucoma patients treated ... to 3 years with the InnFocus MicroShunt® at the 2014 ... . The Summit was held prior ... American Academy of Ophthalmology . The Company also said it ... countries by early 2015. Logo - http://photos.prnewswire.com/prnh/20141016/152617LOGO ...
(Date:10/17/2014)... , Oct. 17, 2014   ndd Medical Technologies ... (PFT) employing precise ultrasound technology, announced that its EasyOne ... Nation Healthcare Center , a 140,000 square foot, 44-bed ... Oklahoma hospital serves a large number of ... Oklahoma and beyond. A portion of ...
Breaking Medicine Technology:Green Park Collaborative to Discuss Comparative Effectiveness and Value of Weight Loss Treatments 2InnFocus Featured at the Ophthalmology Innovation Summit In Chicago 2EasyOne Pro Mobile Respiratory Testing from ndd Medical Technologies Chosen by Choctaw Nation 2
Cached News: