New drug boost for asbestos-related lung cancer sufferers

Clinical trials of a new anticancer drug combination carried out by researchers at Newcastle University show that it has potential to almost double the life expectancy of sufferers of Mesothelioma a form of lung cancer which affects around 1,700 people in the UK every year according to a report published in the Journal of Clinical Oncology.

Mesothelioma is a cancer of the pleura the membranes that lines the inside of the chest and the outside of the lungs. It differs from other types of lung cancer in that it is caused by exposure to asbestos, rather than by smoking. The condition affects five times more men than women, and most commonly develops in men between 50 and 70 years of age.

Mesothelioma is very hard to treat. It is usually inoperable and not very responsive to radiotherapy. With the anticancer drugs previously available, people diagnosed with the disease could expect to survive for only six to eight months.

Now, results of a study by Professor Hilary Calvert, Dr Andrew Hughes and colleagues in the Cancer Research UK-funded Cancer Research Unit at Newcastle University, in collaboration in Eli Lilley, have shown that, on average, patients who were given the new drug, pemetrexed and carboplatin, survived for up to 13 14 months. In a handful of cases, patients have survived for three years or more.

Professor Calvert said: 'The drug combination showed remarkable activity in Mesothelioma. Indeed, our study provided the first convincing demonstration that pemetrexed to carboplatin could be useful in the treatment of the disease'.

Pemetrexed is an experimental drug being developed by pharmaceutical company Eli Lilley under the trade name Alimta. It is an anticancer drug based on being an analogue of the B-vitamin, folic acid. Drugs of this class were first developed by Professor Calvert and colleagues at the Institute of Cancer Research in London in the early 1980s with funding from Cancer Research, leading to the l

Contact: Prof. Hilary Calvert
University of Newcastle upon Tyne

Page: 1 2

Related medicine news :

1. Daily supplement may boost birthweight of babies in the developing world
2. $4 million grant boosts University of Michigan campaign for a new childrens hospital
3. UC Irvines undergraduate research programs receive $900,000 funding boost
4. Calcium boost to youths bones could reduce osteoporosis risk
5. Collaborative care, training boosts adolescent depression treatment in primary care clinics
6. NIAID-sponsored clinical trial aims to boost flu vaccine supply
7. Novel p53 gene-based therapy boosts immune system and reduces tumor size
8. Multi-center study finds therapy boosts kidney transplants in highly sensitized patients
9. Sleep loss boosts appetite, may encourage weight gain
10. Intervention boosts activity in kids, especially minorities
11. Advanced, precise radiation may boost limb-sparing therapy for sarcoma

Post Your Comments:

(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the loss ... author, William Nowers. Captain Nowers and his wife, Millie, have six children, ten ... the Navy. Following his career as a naval aviator and carrier pilot, he ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), ... of an innovative new design of the shoulder pad. The shoulder pad provides ... while controlling your pain while using cold therapy. By utilizing ice and water that ...
(Date:10/12/2017)... ... ... HMP , a leader in healthcare events and education, today announced that ... for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie Awards ... recognizes editorial and design excellence across a range of sectors. This year’s program included ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... $3,296 in property taxes a year. In some states—like New York, New Jersey, ... By contrast, many overseas retirement havens have extremely low property-tax rates, which contributes ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... , Sept. 18, 2017 EpiVax, ... of bioinformatics and immune engineering, today announced ... influenza A (H7N9) vaccine. ... to seasonal influenza and presents a challenge ... prior exposure to be effective. Using state-of-the-art ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform for ... the first annual edition of its Global CSR Risk and Performance Index. ... by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points ... ... ...
(Date:9/12/2017)... SAN FRANCISCO , Sept. 12, 2017 /PRNewswire/ ... Lifecycle Management Solutions (VLMS), is pleased to announce ... as a member of its Board of Directors ... 2017. ValGenesis VLMS enables life science companies to ... eliminate the use of paper in this process. ...
Breaking Medicine Technology:
Cached News: