HOME >> MEDICINE >> NEWS
New gene therapy protocol: First successful treatment for 'bubble babies'

Jerusalem (June 21, 2002) -- A lifesaving protocol that has wide ranging consequences for the successful treatment of genetic diseases has been developed by a team of Israeli and Italian researchers for the treatment of children born without immune systems. A description of the first successful application of the new treatment appears in the June 28 issue of the journal Science.

The procedure, which improves an existing protocol to give a biological advantage to genetically altered stem cells, resulted in a complete reversal of severe combined immunodeficiency (SCID), a condition caused by the lack of an essential enzyme, adenosine draminase (ADA). Children born with an acute form of SCID are known as "bubble babies" and have to be kept in isolation units to prevent them from coming in contact with infectious elements.

The research was led by Prof. Shimon Slavin, Dr. Shoshana Morecki and Dr. Memet Aker of Hadassah-Hebrew University Medical Center in Jerusalem, in collaboration with Dr. Allesandro Aiuti and his colleagues from the San Raffaele Institute for Gene Therapy in Milan, Italy.

According to Slavin, Head of Department of Bone Marrow Transplantation at Hadassah Medical Center, the significance of this new development extends beyond those immediately affected by SCID and has the potential to be equally effective in curing similar genetic diseases, such as Gaucher's and other diseases caused by enzyme deficiency.

"The concept can be applied to all genetic diseases where there is a need to engineer stem cells to produce normal products, especially when patients have no matched donor available for safe bone marrow transplantation," Slavin said.

Conventionally, such patients are usually treated with ADA replacement therapy in an attempt to rescue the immune system. This replacement therapy, however, is not a long-term solution; it is only effective for one or two days at a time and is extremely expens
'"/>

Contact: Roberta Elliott
relliott@hadassah.org
212-303-8153
Hadassah, the Women's Zionist Organization of America
27-Jun-2002


Page: 1 2 3

Related medicine news :

1. Study shows patch therapy may be as effective as oral medications
2. Novel therapy tested in mice could chase away cat allergies
3. Drug therapy may be comparable to invasive cardiac procedures for elderly patients with heart attack
4. Risk of cardiac death after radiotherapy for breast cancer has declined, study finds
5. Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
6. Bevacizumab combined with chemotherapy prolongs survival for some patients with advanced lung cancer
7. Breakthrough in medical research: New chemotherapy gives hope to brain tumour patients
8. Two years after gene therapy treatments, severe angina patients showed prolonged clinical benefit
9. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
10. Cognitive behavioral therapy and medication is effective in the treatment of panic disorder
11. Study finds drug eluting stents as effective as vascular brachytherapy in preventing restenosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/8/2019)... , ... October 08, 2019 , ... ... acquired a majority interest in Advanced Fertility Care (AFC), an advanced reproductive services ... forces to expand the availability of RE services to expectant families throughout Arizona ...
(Date:10/8/2019)... West Hartford, CT (PRWEB) , ... October 08, ... ... surgeons at JawFixers in West Hartford, CT, help patients with missing teeth restore ... each year, this team of oral surgeons relies on advanced i-CAT® 3D Cone ...
(Date:10/8/2019)... (PRWEB) , ... October 08, 2019 , ... Over the ... emerged as a standout in the sports restaurant category by providing a higher-quality product ... delicious new fall menu as well as a "RAISE A MUG FOR THE CAUSE" ...
(Date:10/8/2019)... ... October 08, 2019 , ... Smile Brands Inc. has been named one ... Comparably. Smile Brands, a leading dental support organization with nearly 440 affiliated practices across ... Smiles for Everyone®. The Happiness Award is the latest in a series of ...
(Date:10/8/2019)... NEW YORK (PRWEB) , ... October 08, 2019 ... ... dentist specializing in biomimetic dentistry techniques, has recently attended an advanced Level III ... this emerging area of dentistry. The training took place September 16-19, 2019 at ...
Breaking Medicine News(10 mins):
(Date:10/15/2019)... FORESIDE, Maine (PRWEB) , ... ... ... Standards1 releases VALIDATE® LP2 linearity and calibration verification kit, for Roche cobas® ... A (Apo-A1) and Apolipoprotein B (Apo-B). Each VALIDATE® LP2 kit, liquid, ...
(Date:10/11/2019)... ... October 11, 2019 , ... Five New York fitness studios have teamed up to create ... opportunity to tour and sample a variety of the top group exercise classes offered on ... produced by Club Pilates on W. 57th St., the Hell’s Kitchen Sweat Crawl will feature ...
(Date:10/10/2019)... ... October 10, 2019 , ... Ovation Fertility is once ... of reproductive medicine, with six abstracts accepted for poster presentations at the ASRM ... October 12-16, 2019, in Philadelphia. , “Ovation will have a prominent presence in ...
Breaking Medicine Technology:
Cached News: