New horizons, treatments in anticancer chemistry

common soil bacteria, attacks drug-resistant tumors. Although these agents appear to be much more potent than similar microtubule-stabilizing drugs, they carry a high risk of toxicity. Researchers are taking a variety of approaches to creating analogs that are safer than the natural drug. The first human trial of this experimental class of drug analogs started recently. (Gregory Vite, Ph.D., Bristol-Myers Squibb, Princeton, N.J.; ORGN 286, Monday, March 27, 1:30 p.m., Moscone Convention Center, Room 102, Exhibit Level. See page 141 in the final program.)

  • First oral medication with Taxol®-like activity: A new anticancer agent is poised to become the first orally active medication with a mechanism similar to Taxol®, which stops tumor growth by stabilizing the tiny strands (microtubules) that separate the chromosomes during cell division. Taxol® and other microtubule-stabilizing agents are currently administered by injection or intravenously. The new agent, which appears to be especially promising for the treatment of breast and colon cancer, attacks tumors that are resistant to Taxol® and may have fewer side effects. Known as IDN5109, it is in clinical trials. (Iwao Ojima, Ph.D., State University of New York at Stony Brook, N.Y.; ORGN 245, Monday, March 27, 11:20 a.m., Moscone Convention Center, Room 103, Exhibit Level. See page 140 in the final program.)

  • New anticancer agents from algae: Cryptophycins are derived from blue-green algae. Unlike Taxol® and epithilones, which inactivate microtubules by stabilizing their structure after they form, cryptophycins inhibit tumor growth by preventing the formation of microtubules. A synthetic cryptophycin analog is in Phase I clinical trials. (Chuan Shih, Ph.D., Lilly Research Laboratories, Indianapolis, Ind.; ORGN 291, Monday, March 27, 4:40 p.m., Moscone Convention Center, Room 102, Exhibit Level. See page 141 in the final program.)

  • New ap

  • Contact: Charmayne Marsh
    American Chemical Society

    Page: 1 2 3

    Related medicine news :

    1. Chronic pain treatments more effective when taken together, new study shows
    2. Research offers hope of new treatments for liver damage
    3. Scientist works on innovative treatments for brain tumors
    4. Blacks less likely to get expensive, newer heart treatments
    5. Two years after gene therapy treatments, severe angina patients showed prolonged clinical benefit
    6. Promising treatments for Huntingtons disease identified in UCI study
    7. Research offers hope of new treatments for liver damage plague
    8. Mayo Clinic researchers announce promising next generation treatments for multiple myeloma
    9. New treatments for infertility are unjustified
    10. Study may lead to new means of increasing effectiveness of existing cancer treatments
    11. Controversies regarding ovarian cancer treatments addressed

    Post Your Comments:

    (Date:8/11/2018)... ... ... Dr. Siavash Eftekhari, Oral and Maxillofacial Surgeon at Monarch Dental® in ... to deliver dental care in impoverished communities. Along with a team of fellow ... to help deliver care to over 550 individuals in need. , This outreach was ...
    (Date:8/11/2018)... ATLANTA (PRWEB) , ... August 11, 2018 , ... ... winner of a Silver Stevie® Award in the Executive of the Year-Business category ... the world’s premier business awards program. All individuals and organizations worldwide – public ...
    (Date:8/9/2018)... ... August 09, 2018 , ... ... by simplifying medication adherence monitoring with Smart-pill bottle and mobile applications, DoseSmart ... the App Orchard. , The DoseSmart medication management and medication adherence platform ...
    (Date:8/7/2018)... ... August 07, 2018 , ... Sussex Vision Center, a multi-site optometry practice ... Sussex, OD, founded the practice in Coldwater, and over the last three decades has ... to offer comprehensive eye health services for patients of all ages. , “I ...
    (Date:8/3/2018)... ... August 03, 2018 , ... On August 2, 2018 ... proceedings. Mark Sadaka of Sadaka Associates, LLC has been litigating Zostavax injuries ... before the Judicial Panel on Multidistrict Litigation for the thousands of people injured by ...
    Breaking Medicine News(10 mins):
    (Date:8/3/2018)... ... August 03, 2018 , ... Flexefits, a pioneer in direct -pay, direct access ... allowing participants in Direct Primary Care arrangements to keep HSA eligibility and permit DPC ... individual and $300 per family per month.) , “We are very pleased to see ...
    (Date:8/2/2018)... ... ... UMD Professor Utpal Pal leads a team of investigators across multiple institutions ... of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), ... contribute to the spread of major diseases like Lyme disease. Pal is the project ...
    (Date:8/2/2018)... ... August 02, 2018 , ... ... with customer relationship management (CRM), patient experience and provider communication solutions for ... Program for Health Information Service Providers (HISPs). DirectTrust is a ...
    Breaking Medicine Technology:
    Cached News: