HOME >> MEDICINE >> NEWS
New radioimmunotherapy drug proves highly effective for killing off B cell non-Hodgkins lymphoma

ROCHESTER, MINN. -- A Mayo Clinic study indicates the first of a new class of drugs involving radioimmunotherapy benefited a significant number of patients with low-grade B cell non-Hodgkins lymphoma who have exhausted treatment options.

The study, published in the May 15, 2002, issue of Journal of Clinical Oncology, investigated the ability of the drug Zevalin to hone in on and kill off the non-Hodgkins lymphoma B cells. Zevalin is the first radioimmunotherapy drug developed specifically to fight this common but usually fatal cancer of the lymph glands that, for unknown reasons, is on the increase in the United States. About 56,000 people are diagnosed with this cancer annually.

The randomized study involved 143 patients with B cell non-Hodgkins lymphoma who had previously failed the standard chemotherapy treatments. The study found that 80 percent of patients who received Zevalin experienced a positive response in that their tumor shrunk. That compared to a 56 percent response rate in patients receiving only Rituxan, another drug used to treat the cancer.

Most noteworthy, 30 percent of the patients receiving Zevalin achieved complete remission with no evidence of the cancer present, compared to only 16 percent of patients taking Rituxan.

Radioimmunotherapy combines monoclonal antibodies, which are antibodies produced in a laboratory to react against a cancer cell, with the ability of radiation to kill off cancer cells. The mixture of radiation and antibodies is given intravenously and travels through the bloodstream to the cancer cells.

Unlike chemotherapy which goes through the whole body, Zevalin carries the radiation payload directly to the tumor, says Thomas Witzig, M.D., a Mayo Clinic hematologist. The drug radiates only about a five millimeter area around the tumor.

Along with its ability to hone in on cancer cells, the drug is easier on patients physically.

One treatment is required on an outpatient ba
'"/>

Contact: Mary Lawson
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
13-May-2002


Page: 1 2

Related medicine news :

1. New radioimmunotherapy cancer treatment
2. Hormonal treatment improves survival in high-risk prostate cancer patients
3. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
4. MRI proves useful in assessment of suspected breast cancer patients
5. New substance that improves the photodetection of bladder cancer gains market approval
6. Most advanced CT scanner improves imaging of heart, avoids need for surgical inspection
7. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
8. New test improves detection of bladder cancer
9. New mosquito control strategy proves successful against dengue fever
10. Study proves catheter ablation safe for patients
11. Adding radiation therapy to chemotherapy improves survival in patients with high-risk breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: