HOME >> MEDICINE >> NEWS
New research suggests two brain areas critical for short-term memory

ood as an incentive, the rat pressed the lever and then had to perform another behavior on the opposite side of the cage for 1 second to 30 seconds as a distraction. When the animal returned after the delay, both the "right" and "left" levers were showing. To get the task correct, the rat now had to press the lever opposite from the one selected at the beginning of the trial.

Electrode recordings of cell activity in both brain areas unexpectedly showed that when the imposed delay was less than 15 seconds, only the subiculum recorded the information. But, when the delay was longer, the subiculum became inactive while the hippocampus switched on and took over control of the memory requirements of the task.

The research also revealed another important finding about the hippocampus. When it switched on to complete the trial, the memory was biased by past experience. This strategy allowed the hippocampus to anticipate future events based on past outcomes.

With the rat trials, the hippocampus did not start from scratch. Because of this strategy in some cases it would "expect" the trials to alternate "left," then "right," and fired cells to remember the alternate lever even before the trial began.

"When the hippocampus relies on previous experience, and doesn't use current events, the rat can get the task wrong because the anticipatory firing is actually controlling the animal's behavior," said Hampson.

In humans, this is similar to someone who takes the same highway exit each day to get to work. He may end up taking that route even when he's not supposed to such as on a day he needed to go to the dentist before work.

"When this happens, you're using a behavioral pattern that is remembered by your hippocampus," said Deadwyler. "When you get in your car in the morning, you trigger that pattern and your hippocampus then takes over. Based on familiar landmarks, it then guides you toward your destination. But, you're acting in
'"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-6878
Wake Forest University Baptist Medical Center
12-May-2004


Page: 1 2 3

Related medicine news :

1. Public morally obliged to take part in scientific research, says leading ethicist
2. U of M researcher says Viagra may cause permanent vision loss in some men
3. Indiana University researchers closer to helping hearing-impaired using stem cells
4. Can you read my mind? W.M. Keck Foundation funds innovative brain research at Carnegie Mellon
5. RIT takes eye-tracking research to next level
6. UW research shows risk factors for relapse among health care professionals who abuse drugs
7. Protein that helps skin cancer spread identified by Stanford researchers
8. US life expectancy about to decline, researchers say
9. Ethical discussion should come before research
10. Philanthropist Paul F. Glenn launches labs for aging research at Harvard Medical School
11. Gene for age-related macular degeneration discovered by Yale researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global ... and affordable online education – is proud to announce its new master’s degree ... of its kind in the nation, the 60-credit hour program is designed to ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to the ... percent of each hotel room booked with a special new rate code to benefit ... (RMHC-CNI) , effective immediately. Donations will be applied to any room type, any ...
(Date:8/28/2020)... ... August 28, 2020 , ... Ernst & ... was named an Entrepreneur Of The Year® 2020 Florida Award finalist. Now in ... whose ambitions deliver innovation, growth and prosperity as they build and sustain successful ...
(Date:8/28/2020)... ... August 28, 2020 , ... Integrated Viral Protection ... the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air Protection System ... True North Classical Academy plans to fully reopen equipped with the filtration system on ...
(Date:8/27/2020)... ... 27, 2020 , ... The team at Sikara MedSpa is ... retreat. The practice is centered on results and providing the ultimate patient experience ... to be a sanctuary for total body renewal and aesthetic revitalization, Sikara Medspa ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... , ... While coronavirus cases continue to increase across the country, blood drives ... closed. Because about 80% of blood donations are made at drives hosted by these ... drive hosts to ensure blood products are readily available for patients. , Those ...
(Date:8/31/2020)... , ... August 31, 2020 , ... If you live in New York City you ... estate part makes sense, it’s the law of supply and demand, but are plastic surgeons ... has a significant percentage of their patients that make the four-hour trip to have expert ...
(Date:8/28/2020)... ... ... Dr. Mark Surrey has been in practice for over 25 years. He ... the Department of OBGYN at UCLA’s David Geffen School of Medicine. , He ... is a Clinical Director of Fellowship Training for UCLA & Cedars Sinai Reproductive Endocrinology. ...
Breaking Medicine Technology:
Cached News: