HOME >> MEDICINE >> NEWS
New study: Small, frequent doses of caffeine best strategy for staying awake

Boston, MA - May 11, 2004 - Caffeine is the world's most widely-used stimulant yet, scientists still do not know exactly how it staves off sleep. Researchers at Brigham and Women's Hospital, Harvard Medical School and other institutions have now discovered that caffeine works by thwarting one of two interacting physiological systems that govern the human sleep-wake cycle. The researchers, who report their findings in the May issue of the journal Sleep, propose a novel regimen, consisting of frequent low doses of caffeine, to help shift workers, medical residents, truck drivers, and others who need to stay awake get a bigger boost from their tea or coffee.

" Most people take a huge jolt of coffee in the morning to jumpstart their day-they get the super grande latte from Starbucks," said Charles Czeisler, who was recently appointed the Frank Baldino Jr. PhD professor of sleep medicine at Harvard Medical School. "Their caffeine levels soar only to fall as the day progresses in the face of rising sleepiness. They might be better off taking much smaller more frequent doses of caffeine, equivalent to a quarter of a cup of coffee, as the day wears on."

Though many studies have measured caffeine's sleep-averting effects, most do not take into account that sleep is governed by two opposing but interacting processes. The circadian system promotes sleep rhythmically-an internal clock releases melatonin and other hormones in a cyclical fashion. In contrast, the homeostatic system drives sleep appetitively-it builds the longer one is awake. If the two drives worked together, the drive for sleep would be overwhelming. As it turns out, they oppose one another.

Czeisler, who also leads the Division of Sleep Medicine at HMS, and his colleagues had reason to suspect that caffeine might be working to blunt the homeostatic system. For one thing, caffeine is thought to block the receptor for adenosine, a critical chemical messenger involved in the homeostatic dri
'"/>

Contact: Judith Montminy or Misia Landau
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
11-May-2004


Page: 1 2 3 4

Related medicine news :

1. UNC study: Most N.C. family practitioners engage in unrecognized community service
2. UCLA study: Nearly a third of drug ads in medical journals contain no references for medical claims
3. More homeless mentally ill than expected according to UCSD study: Interventions urged
4. Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
5. Mouse study: Signal overload in Alzheimer brains
6. OHSU study: Testosterone deprivation makes men forget
7. Mayo Clinic led study: Minimally invasive surgery safe, effective for patients with colon cancer
8. OHSU study: Rate of brain volume loss predicts dementia
9. Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
10. National study: Health care access for poor children improves, but gap in care for uninsured grows
11. UCSF study: Pediatricians judgment often better than clinical guidelines for treating infant fever

Post Your Comments:
(Date:6/30/2015)... Church, VA (PRWEB) , ... June 30, 2015 ... ... 29th Annual Conference will be held October 28-31, 2015 at Disney’s Coronado Springs ... of continuing nursing education and networking. Each year, this premiere event for psychiatric-mental ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... This Fourth ... aligned with the Peacock Alley story including hard work, tenacity, perseverance, commitment to quality, ... was born. , Born of Mary Ella Gabler's simple love of quilts, Peacock ...
(Date:6/29/2015)... ... June 30, 2015 , ... Sublime Beauty NATURALS® introduces its new USDA Certified ... ideal for natural skincare and even culinary uses, was especially designed for Oil Pulling. ... desire, and Oil Pulling can accomplish this. Oil Pulling is an Ayurvedic practice that ...
(Date:6/29/2015)... Grove, Utah (PRWEB) , ... June 30, 2015 , ... ... pleased to announce its involvement in a much-needed autism support center, planned at Utah ... from the Regents formal approval for the center and the building in which it ...
(Date:6/29/2015)... ... June 29, 2015 , ... Healthpointe, one of Southern ... A. Mitamura, MD., PhD into their world-class multidisciplinary team of physicians and specialists. ... Beach , Irwindale and La Tijera-Los Angeles. , Orthopedic surgeons of Healthpointe, ...
Breaking Medicine News(10 mins):Health News:American Psychiatric Nurses Association 29th Annual Conference: Continuing Education and Collaboration in Psychiatric-Mental Health and Nursing 2Health News:American Psychiatric Nurses Association 29th Annual Conference: Continuing Education and Collaboration in Psychiatric-Mental Health and Nursing 3Health News:Luxury Linen Purveyor Peacock Alley Celebrates the Fourth of July 2Health News:New Product: Transform Wellness and Oral Health With This Ancient Ayurvedic Secret and Organic Product from Sublime Beauty NATURALS® 2Health News:doTERRA Partners With Utah Valley University on Autism Support Center 2Health News:doTERRA Partners With Utah Valley University on Autism Support Center 3Health News:Renowned Orthopedic and Spine Surgeon Joins Healthpointe in Long Beach 2Health News:Renowned Orthopedic and Spine Surgeon Joins Healthpointe in Long Beach 3
(Date:6/30/2015)... Legal-Bay LLC, the Lawsuit Settlement Funding Company, announced today ... (MDL) over the Zimmer NexGen Knee implant lawsuits has ... There are currently more than a thousand cases against ... judge in Illinois . The judge ... October of this year. Zimmer Inc. previously issued voluntary ...
(Date:6/30/2015)... 2015 PharmaVentures is pleased to ... Technologies Oy (CMT) on its divestment of certain assets ... CMTs world leading capabilities in cellular imaging and analysis. ... series of successful global deals in the life science ... Fintan Walton , CEO, PharmaVentures, commented: "PharmaVentures is delighted ...
(Date:6/29/2015)... Mordor Intelligence presents their Global Pharmaceutical Packaging Market ... Metal) - ByType of Packaging (Ampules, Blister Packs, Bottles, Canisters, ... By Geographical Region ( North America , ... Latin America , Middle East ... Industry Value Chain Analysis, Porter,s 5 Force Analysis, Drivers, Restraints, ...
Breaking Medicine Technology:Legal-Bay Lawsuit Settlement Funding Reports Zimmer NexGen Knee Bellwether Trial to Begin October 13th, 2015 2Legal-Bay Lawsuit Settlement Funding Reports Zimmer NexGen Knee Bellwether Trial to Begin October 13th, 2015 3PharmaVentures Completes M&A Deal for Technology in the Stem Cell & Regenerative Medicine Sector 2Global Pharmaceutical Packaging Market - North America and Europe Expected to Lead Followed by the Asia Pacific Market 2Global Pharmaceutical Packaging Market - North America and Europe Expected to Lead Followed by the Asia Pacific Market 3
Cached News: