HOME >> MEDICINE >> NEWS
New study: Small, frequent doses of caffeine best strategy for staying awake

Boston, MA - May 11, 2004 - Caffeine is the world's most widely-used stimulant yet, scientists still do not know exactly how it staves off sleep. Researchers at Brigham and Women's Hospital, Harvard Medical School and other institutions have now discovered that caffeine works by thwarting one of two interacting physiological systems that govern the human sleep-wake cycle. The researchers, who report their findings in the May issue of the journal Sleep, propose a novel regimen, consisting of frequent low doses of caffeine, to help shift workers, medical residents, truck drivers, and others who need to stay awake get a bigger boost from their tea or coffee.

" Most people take a huge jolt of coffee in the morning to jumpstart their day-they get the super grande latte from Starbucks," said Charles Czeisler, who was recently appointed the Frank Baldino Jr. PhD professor of sleep medicine at Harvard Medical School. "Their caffeine levels soar only to fall as the day progresses in the face of rising sleepiness. They might be better off taking much smaller more frequent doses of caffeine, equivalent to a quarter of a cup of coffee, as the day wears on."

Though many studies have measured caffeine's sleep-averting effects, most do not take into account that sleep is governed by two opposing but interacting processes. The circadian system promotes sleep rhythmically-an internal clock releases melatonin and other hormones in a cyclical fashion. In contrast, the homeostatic system drives sleep appetitively-it builds the longer one is awake. If the two drives worked together, the drive for sleep would be overwhelming. As it turns out, they oppose one another.

Czeisler, who also leads the Division of Sleep Medicine at HMS, and his colleagues had reason to suspect that caffeine might be working to blunt the homeostatic system. For one thing, caffeine is thought to block the receptor for adenosine, a critical chemical messenger involved in the homeostatic dri
'"/>

Contact: Judith Montminy or Misia Landau
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
11-May-2004


Page: 1 2 3 4

Related medicine news :

1. UNC study: Most N.C. family practitioners engage in unrecognized community service
2. UCLA study: Nearly a third of drug ads in medical journals contain no references for medical claims
3. More homeless mentally ill than expected according to UCSD study: Interventions urged
4. Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
5. Mouse study: Signal overload in Alzheimer brains
6. OHSU study: Testosterone deprivation makes men forget
7. Mayo Clinic led study: Minimally invasive surgery safe, effective for patients with colon cancer
8. OHSU study: Rate of brain volume loss predicts dementia
9. Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
10. National study: Health care access for poor children improves, but gap in care for uninsured grows
11. UCSF study: Pediatricians judgment often better than clinical guidelines for treating infant fever

Post Your Comments:
(Date:2/27/2015)... CA (PRWEB) February 27, 2015 ... Devices (IPD), has introduced miniature, wire bondable, silicon ESD ... Power LED markets. The ESD88NP and ... currents away from sensitive LED and IC products. ... Multilayer Varistors (MLV). All devices meet the requirements ...
(Date:2/27/2015)... (PRWEB) February 27, 2015 Just a ... air for those suffering from Sjögren’s Syndrome after a ... by researchers at the University of Buffalo and Immco ... of research was to develop a new diagnostic ... the presence of new autoantibodies. Researchers aimed to develop ...
(Date:2/27/2015)... 27, 2015 Today, February 27th, is "Shine ... , along with LXR Organics and Living ... Campaign to raise awareness and promote prevention, rescue and restoration ... by the END IT Coalition, slavery is the 2nd largest ... exists in 167 countries around the world. Slavery includes bonded ...
(Date:2/27/2015)... February 27, 2015 Clinovo, a leading ... validated Electronic Data Capture (EDC) at the CALBIO2015 ... March 2nd and March 3rd at Booth # 141. ... and DIY CRF and edit-check builder allowing Clinical Trials ... matter of days, without any programming experience. Clinovo’s new ...
(Date:2/27/2015)... Laguna Hills, CA (PRWEB) February 27, 2015 ... has been chosen as their Sage ERP Document Management ... ERP, Sage 300 ERP, Sage CRM and other complimentary ... ADSS Global have worked side-by-side for many years to ... their Sage ERP applications. , “We are thrilled ...
Breaking Medicine News(10 mins):Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 2Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 3Health News:Breakthrough Blood Test for Early Detection of Sjögren’s Syndrome Now Available 2Health News:KAJ Brothers Join the Campaign to 'End It - Shine A Light On Slavery' 2Health News:Clinovo to Demo Its Self-Service, Cloud-Based EDC Solution at CALBIO2015 on March 2nd and 3rd, 2015 2Health News:Altec Announces 2014 Sage ERP Document Management Partner of the Year Award Recipient 2
(Date:2/26/2015)... , Feb. 26, 2015  IRIDEX Corporation (NASDAQ: ... quarter and full year 2014 financial results after the market ... with the release, the Company will host a conference call ... on Thursday, March 5, 2015 to discuss ... Interested parties may access the live conference call via ...
(Date:2/26/2015)... , Feb. 26, 2015 Legislation passed ... a pharmacy provision to help prevent inappropriate prescriptions in ... Protecting the Integrity of Medicare Act (PIMA) of ... Chairman Kevin Brady (R-TX) and Ranking Member ... prescription drug abuse epidemic and implement the right policies, ...
(Date:2/26/2015)... and Markets ( http://www.researchandmarkets.com/research/2vn6hh/radiation_therapy ) has announced ... Global Strategic Business Report" report to their offering. ... for Radiation Therapy Equipment in US$ Million by the ... Radiation Therapy Simulator. The report provides separate comprehensive analytics ... Japan , Europe , ...
Breaking Medicine Technology:IRIDEX Announces Fourth Quarter and Full Year 2014 Conference Call and Release Date 2PCMA Statement on the 'Protecting the Integrity of Medicare Act' 2Radiation Therapy Equipment - Global Strategic Business Report 2015-2020: Linear Accelerator, Treatment Planning Systems, and Radiation Therapy Simulator 2
Cached News: