HOME >> MEDICINE >> NEWS
Newborns with heart defect have low blood flow in brain before surgery

As survival rates have steadily improved for children with heart defects, physicians have focused more attention on improving quality-of-life factors such as neurological and cognitive abilities. A new study shows that newborns with congenital heart disease often have abnormally low blood flow in their brains before they undergo surgery.

Researchers from The Children's Hospital of Philadelphia led the study, published in the December issue of The Journal of Thoracic and Cardiovascular Surgery.

One of every 100 children is born with a heart defect--one-third of which are severe enough to require surgery during the newborn period. Many of those high-risk children are identified as having neurological and cognitive problems during the months and years that follow. While some of these problems may be related to the complexity of the surgery, evidence is mounting that abnormal neurological conditions play a role even before surgery.

The current study, which used a novel magnetic resonance imaging (MRI) technique developed by members of the investigative team, was the first to measure the infants' cerebral blood flow before surgery. The reduced blood flow was associated with abnormal features in the newborn brain, according to pediatric neurologist Daniel J. Licht, M.D., who led the multidisciplinary research team at Children's Hospital.

"Some of the neurodevelopmental problems that these children experience may be attributable to necessary surgical practices such as heart-lung bypass," said Dr. Licht. "However, many infants with heart defects have neurological abnormalities before surgery."

The research team at The Children's Hospital of Philadelphia studied 25 newborns born at term with congenital heart defects. They found cerebral blood flow to be significantly lower than in healthy newborns, sometimes drastically reduced. The low blood flow was also associated with a condition called periventricular leukomalacia (PVL),
'"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
7-Dec-2004


Page: 1 2

Related medicine news :

1. How Little Is Too Little For A Babys Safety? UT Southwestern Researchers Shed New Light On Size And Morbidity/Mortality In Newborns
2. Infrared Thermometers A Good Alternative For Use On Newborns
3. Postmature Infants Not As Easily Calmed As Other Newborns
4. Maternal Exposure To Crack Cocaine Produces Stressed Newborns
5. Use Of Surfectant Therapy Widens Gap In Death Rate Of Black And White Newborns
6. New study in Nature demonstrates protection against cell death during heart attack
7. Uric acid and heart disease
8. Researchers search for first sign of congestive heart failure
9. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
10. Extreme exertion, emotion can spark repeat heart attacks
11. Men with severe sleep breathing disorder have higher risk of heart problems

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2018)... ... 2018 , ... Gastro Health, LLC (“Gastro Health”), one of ... Simon Frisch and Chris Weinstein, who have been appointed Senior Vice President, Strategic ... time of tremendous growth for the group, which has increased its physician headcount ...
(Date:8/14/2018)... ... August 14, 2018 , ... Eagle Merchant ... a leading provider of residential and commercial recreational surfacing products across the country. ... with products used across a wide range of markets and customers. Founded in ...
(Date:8/11/2018)... OVERLAND PARK, Kan. (PRWEB) , ... August 10, ... ... Gout Gone, an industry leader in Gout Relief. , What is gout? This ... the lower extremities as a result of high levels of uric acid. Other ...
(Date:8/11/2018)... ... August 11, 2018 , ... Financial Voyages LLC CEO Pamela ... of the Year-Business category in The 15th Annual International Business Awards®. , The ... organizations worldwide – public and private, for-profit and non-profit, large and small - ...
(Date:8/9/2018)... ... August 09, 2018 , ... Balboa ... a new verification process that substance abuse providers must pass in order to ... can reach more people to help.” , Helping people is what Balboa ...
Breaking Medicine News(10 mins):
(Date:8/15/2018)... (PRWEB) , ... August 15, 2018 , ... ... to their expansive lineup of casters. The newly designed Diamond Series features ... and stability. Manufactured with an antimicrobial compound injected into a thermoplastic resin ...
(Date:8/14/2018)... OXNARD, Calif. (PRWEB) , ... August 14, 2018 ... ... completion of Harvest Academy, their first-ever summer harvest employment and hands-on educational program ... were currently enrolled in a high school, junior college or university, spent a ...
(Date:8/11/2018)... ... August 11, 2018 , ... ... Monday, August 13, with fun, games and gifts. Left-Handers are possibly the world’s ... for right-handers. Having endured centuries of prejudice, countless indignities and inconveniences, left-handers quietly ...
Breaking Medicine Technology:
Cached News: