HOME >> MEDICINE >> NEWS
Nighttime is the right time to prevent preterm labor with aspirin

ORLANDO, Sept. 26 Low-dose aspirin prevented preterm labor in pregnant women at risk for high blood pressure, but only if they started therapy before the 16th week of pregnancy, and only if they took it at night, according to research presented today at the American Heart Association's 56th Annual High Blood Pressure Research Conference.

"This is the first study to show that aspirin at bedtime works and aspirin at awakening does not," says lead author Ramon C. Hermida, Ph.D., director of the bioengineering and chronobiology laboratories and a professor at the University of Vigo in Vigo, Spain. He added that earlier studies may have had conflicting results because they used lower aspirin doses, started therapy later in pregnancy or gave it at different times of the day.

The double-blind, randomized controlled trial followed 341 pregnant women who were at high risk for blood pressure problems due to obesity, family or personal history of gestational high blood pressure or preeclampsia, or a history of miscarriage.

The women were divided into six groups and given 100 mg of aspirin or placebo at one of three times: on awakening, eight hours later or at bedtime. Treatment started at 12 to 16 weeks of pregnancy.

Compared with placebo, there was no effect on blood pressure when aspirin was taken in the morning. However, blood pressure was significantly reduced when the women took aspirin eight hours after awakening and, to a greater extent, when they took it at night. When aspirin was taken at bedtime, the differences between the aspirin and placebo groups were significant: The incidence of preeclampsia was 14.3 percent in the placebo group, but just 1.7 percent in the aspirin group. Gestational hypertension occurred in 30.4 percent of women in the placebo group, but only 6.8 percent in the aspirin group. Also, 17.9 percent of women in the placebo group had pre-term labor, while none of the women taking aspirin delivered early.

"All t
'"/>

Contact: Maggie Francis
maggie.francis@heart.org
214-706-1397
American Heart Association
26-Sep-2002


Page: 1 2

Related medicine news :

1. Nighttime Asthma Squeezes School Attendance
2. New rights to access, but for most transparency is still as clear as mud
3. Getting the fluid balance right in malaria
4. GMC is right to appeal over life prolonging treatment
5. Left and right ears not created equal as newborns process sound, finds UCLA/UA research
6. Vietnamese doctor to receive human rights award from NY Academy of Sciences
7. Even drug-resistant HIV infection responds to right treatment
8. Bright clothing and white helmets cut motorcycle deaths
9. Human rights abuses common in southern Iraq between 1991 and 2003
10. Making smart drugs that deliver the right kind of punch
11. Prototype system developed by Wright State computer engineer allows blind to see

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: