No adverse effects of aluminium in vaccines

Writing in the February issue of The Lancet Infectious Diseases, Tom Jefferson and colleagues (Cochrane Vaccines Field, Rome, Italy) report that aluminium in vaccines for diphtheria, tetanus, and pertussis causes no serious or long-lasting adverse effects.

Aluminium salts (potassium aluminium sulphate, aluminium sulphate, or aluminium hydroxide) have been used for decades in vaccine formulations as adjuvants (non-specific stimulators of the immune response), and in this role they are vital to the protective efficacy of vaccines. But aluminium has been blamed for side-effects in vaccine recipients, such as local reactions at the site of vaccination and a chronic progressive syndrome called macrophagic myofasciitis. However, replacing aluminium with another adjuvant would be a massive undertaking because all such vaccines would have to be tested in clinical trials and relicensed; besides, no obvious replacement is available.

After an exhaustive trawl of the medical literature for relevant studies, Jefferson and colleagues collected data for a meta-analysis from five published trials. The authors compared adverse events in two settings: vaccines containing aluminium hydroxide versus no adjuvant for children aged up to 18 months, and vaccines containing different types of aluminium versus no adjuvant in children aged 10-16 years. Although aluminium-containing vaccines were more likely than plain vaccines to cause erythema (redness) and induration (hardening of the skin) in young children, and local pain lasting up to 14 days in the older children, there was no evidence that the aluminium-containing vaccines were responsible for serious or long-lasting side-effects.

Jefferson and colleagues recommend-unusually, perhaps, for modern medicine-that no further research be done on this topic.


Contact: Joe Santangelo

Page: 1

Related medicine news :

1. Alcohol relapse adversely affects 10-year liver transplant survival
2. Most adverse events in hospitalized children are preventable
3. Examination of possible conflicts of interest to influence look at suspected adverse drug reactions
4. Panel offers recommendations for monitoring adverse events from dietary supplements
5. Calcium channel blocker reduces adverse cardiovascular events in certain patients
6. Drug companies should disclose adverse events before licensing
7. Study documents adverse events of pneumococcal vaccine in children
8. Patient safety study provides first national estimate of adverse events in Canadian hospitals
9. Timing of adverse events in hospital patients
10. Inadequate water and sanitation adversely effects child growth
11. Survey shows benefits of prescription drug advertising, few adverse effects

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: