HOME >> MEDICINE >> NEWS
Non-pathogenic bacteria block inflammatory response pathway in intestinal tract

uisitely sensitive to bacteria and their products. Now we have found a mechanism by which non-pathogenic bacteria block the inflammatory pathway and prevent cells in the G.I tract from responding as any other cell would respond. This mechanism for tolerance also could be fundamental to the pathogenesis of inflammatory bowel disease (Crohn's disease and ulcerative colitis) and to other infectious intestinal diseases," he said.

Crohn's disease and ulcerative colitis are diseases in which individuals develop a chronic and debilitating intestinal inflammatory response. Inflammatory bowel disease is one of the last few major unexplained diseases, although scientists have long suspected that it is related to lack of tolerance to the community of intestinal organisms. There is a possibility that the balance of beneficial to non-beneficial bacteria is altered in these patients," explains Dr. Neish. "A genetic flaw in the epithelial lining of the G.I. tract could also cause an abnormal response to the non-pathogenic bacteria."

The discovery also may shed light on the growing field of probiotics, in which investigators are experimenting with various species of benign bacteria that can be ingested with foods, such as lacto-bacillus (found in yogurt), to improve the intestinal health of patients with inflammatory bowel disease. The Emory research could elucidate a potential mechanism for the positive effects of probiotics.

"It's interesting that the organisms we are studying are non-pathogenic and have no ability to elicit inflammation themselves, yet they are able to block inflammatory pathways and create tolerance for themselves and perhaps other organisms," said Dr. Neish. "It turns out that some non-pathogenic bacteria have a significant reciprocal ecological interaction with the host. The host can mount an immune response to control resident bacteria, but even non-pathogenic bacteria have an ability to influence that immune response."


'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
31-Aug-2000


Page: 1 2

Related medicine news :

1. Oral bacteria may predict pregnancy outcomes
2. Study finds direct association between cardiovascular disease and periodontal bacteria
3. Substance protects resilient staph bacteria
4. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
5. Bacteria-killing vs. bacteria-inhibiting drugs in treating infections
6. Patients undergoing weight loss surgery have high rates of H pylori bacteria
7. Outbreak of skin infections sheds light on risk factors for bacterial resistance
8. Popular chewing gum eliminates bacteria that cause bad breath
9. Antibiotic resistant bacteria frequently transmitted between intensive care patients
10. New weapon to combat resistant bacteria
11. High level of antibiotic resistance in bacteria that cause food poisoning

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “America On ... Christian identity. “America On The Brink” is the creation of published author, William ... several great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
(Date:10/12/2017)... ... , ... On Saturday, October 21, the Health & Wellness Center at Florida ... money for the American Heart Association Heart Walk. Teams of up to 10 people ... keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra ... care advancements to physician colleagues, skilled nursing facility medical directors and other clinicians ... Waters of Wound Care." , "At many of these conferences we get to ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... Sept. 25, 2017  EpiVax, Inc., a leader ... and immune-engineering today announced the launch of EpiVax ... of personalized therapeutic cancer vaccines. EpiVax has provided ... access to enabling technologies to the new precision ... lead EpiVax Oncology as Chief Executive Officer. Gad ...
(Date:9/22/2017)... Sept. 22, 2017 AVACEN Medical (AVACEN) announced ... now successfully helping those with the widespread pain associated ... diagnosed Amanda in Essex, England ... my hair, experiencing no sleep at all, tremendous pain, ... I cannot recommend [the AVACEN 100] enough, how this ...
(Date:9/18/2017)... , Pa. and KALAMAZOO, Mich. , ... Allentown, Penn. , and OptiMed Specialty Pharmacy of ... business partnership to offer a strategic hub service that ... Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, and ... A spirometer is a medical device used to ...
Breaking Medicine Technology:
Cached News: