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Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy

amps in 5 percent, and one out of 250 women per year experienced blood clots.

"Raloxifene and other SERMS are an exciting class of compounds but we need to learn a lot more about how they can best be used," said Dennis Black, MD, UCSF professor of medicine and epidemiology and one of the co-authors of the study. "This study adds an important piece of the puzzle."

Raloxifene was approved for the prevention of osteoporosis in the US by the Food and Drug Administration in December 1997. In Europe, the drug was recently approved for both the treatment and prevention of osteoporosis. It is marketed as Evista by Eli Lilly and Co., the sponsors of the clinical trials of the treatment.

Other researchers on the study are L.V. Avioli, C. Christiansen, F.J. Cohen, P.D. Delmas, S. Eckert, H.K. Genant, C.C. Gluer, R.K. Knickerbocker, K. Krueger, P. Lips, B.H. Mitlak, T. Nickelsen, J. Stakkestad, and J.R. Zanchetta.


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Contact: Kathleen Barco
kathleen.m.barco@kp.org
(626) 405-5534
University of California - San Francisco
14-Sep-1998


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