HOME >> MEDICINE >> NEWS
Novel technique may help detect certain head and neck cancers

CHICAGO Researchers may be able to detect head and neck squamous cell cancer (HNSCC) earlier by testing for newly discovered signature protein patterns found in patients with this cancer, according to an article in the January issue of The Archives of Otolaryngology, one of the JAMA/Archives journals.

HNSCC represents 5 percent of all cancers in the United States, and an even larger proportion of cancers worldwide, according to the article. Tobacco and alcohol use are well-established risk factors for HNSCC. Despite advances in treating these cancers, little progress has been made in improving survival rates, partially because HNSCC is usually discovered in advanced stages. Even though early diagnosis is imperative for successful treatment of cancer, no accepted screening tests exist for HNSCC, the article states.

Scientists have been searching for biomarkers that can identify the presence of HNSCC. Biomarkers are molecular or biochemical features or signatures that can indicate disease. Newly developed technology that can rapidly screen blood samples for multiple proteins, has enabled scientists to more effectively search for protein biomarkers of disease, including HNSCC.

J. Trad Wadsworth, M.D., from Eastern Virginia Medical School, Norfolk, and colleagues investigated whether the new protein "profiling" technology could help them identify protein signatures specific to patients with HNSCC.

The researchers screened blood serum samples from 99 patients with HNSCC, 25 "healthy" smokers, and 102 healthy (normal) controls.

The researchers discovered several protein profiles that were present more commonly in patients with HNSCC than in healthy smokers or control patients. Using these protein patterns to develop a classification system, the researchers were able to distinguish between patients with HNSCC and normal and healthy smokers with high accuracy (80 percent to 92 percent).

"We
'"/>

Contact: Doug Gardner
757-446-6070
JAMA and Archives Journals
19-Jan-2004


Page: 1 2

Related medicine news :

1. Novel therapy tested in mice could chase away cat allergies
2. Novel antibiotic shows promise in shortening treatment duration of tuberculosis
3. Novel p53 gene-based therapy boosts immune system and reduces tumor size
4. Novel drugs help solve Gleevec resistance
5. Novel imaging technique shows abnormal brain anatomy in children with ADHD
6. Novel drug-antidote strategy provides greater control of drug action
7. Novel imaging technique shows lymph nodes, metastases in breast cancer without surgery
8. Novel delivery method for nutrients wins Kaye Innovation Award for Hebrew university students
9. Novel vitamin discovery offers clues for cancer chemotherapy and lipid disorders
10. Novel findings about neovessel formation
11. Novel MRI technique provides clear images of blood flow

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: