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OHSU doctors use 'putty' to prevent hemorrhagic stroke

r right internal carotid artery, behind her eye under the frontal lobe, and Pardee's was in his left internal carotid artery, also behind the eye appear to show the malformations are gone.

"My before-and-after pictures are incredible," Pardee said. "You can't tell it's there. I saw that and I thought, 'Yeah, OK, this is good!'"

Turner had a similar response: "I was amazed it made the aneurysm much smaller," she said of the procedure. "It did seem like it drew it down. Now there's just a hump instead of a balloon. It's good stuff."

Had the aneurysms burst, the likely result would have been a subarachnoid hemorrhage, a type of stroke in which blood escapes into the space between the brain and the skull, cutting off its flow to the brain.

A common treatment for an aneurysm is coiling, in which a tiny platinum coil is inserted into the sac through a catheter and deployed, restricting blood flow into the malformation. But the coil can fall out of the sac and back into the artery, and sometimes blood flow into the sac isn't fully restricted.

"Coils can stick out, and sometimes you can't get the coil where you need it," Clark said. And there is a 20 percent aneurysm recurrence rate among coiling patients.

But in the Onyx procedure, an angioplasty balloon can be used to hold the liquid inside the sac while it's being injected, preventing it from falling out before it solidifies.

"The balloon keeps it out of the artery and once it hardens, the balloon is deflated and it stays there," Barnwell said.

The other solution for an aneurysm is surgical clipping, in which a tiny metal clip is placed on the neck of the aneurysm to pinch off blood flow into the sac. But the clip stays in the patient forever, and the procedure requires brain surgery and months of recovery.

The Onyx procedure takes the same amount of time as coiling about an hour although it's more complex. "But once we get some experience w
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Contact: Jonathan Modie
modiej@ohsu.edu
503-494-8231
Oregon Health & Science University
30-Oct-2003


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