HOME >> MEDICINE >> NEWS
Older women can benefit from chemotherapy to treat breast cancer

Age alone should not prohibit the use of chemotherapy regimens in older women with breast cancer who are otherwise in good general health, according to a study in the March 2 issue of JAMA.

"The incidence of breast cancer increases with increasing age, and almost half of all new breast cancers in the United States occur in women 65 years of age or older," the authors note in background information in the article. "Systemic adjuvant (secondary treatment) chemotherapy in women with early-stage breast cancer significantly improves both relapse-free and overall survival in women aged 50 to 69 years old, but data are lacking for women aged 70 years or older." The authors add that available data suggest that adjuvant chemotherapy may be significantly underused in older patients or that inappropriate dose reductions are made that decrease its effectiveness.

Hyman B. Muss, M.D., from the Vermont Cancer Center, Burlington, Vt., and investigators from the Cancer and Leukemia Group B (CALGB) analyzed data from four randomized clinical trials of treatments for lymph node-positive breast cancer cases between 1975 and 1999. These trials compared more aggressive with less aggressive chemotherapy regimens. A total of 6, 487 women with lymph node-positive breast cancer were included in the trials; 542 (8 percent) of the patients were 65 years or older and 159 (2 percent) were 70 years or older.

" smaller tumor size, fewer positive lymph nodes, more chemotherapy, and tamoxifen (drug used to treat breast cancer) use were all significantly related to longer disease-free and overall survival," the authors found in their analyses of the studies. "There was no association between age and disease-free survival. Overall survival was significantly worse or patients aged 65 or older because of death from causes other than breast cancer. Thirty-three deaths (0.5 percent of all patients) were attributed to treatment, and older women had higher treatment-relate
'"/>

Contact: Jennifer Nachbur
802-656-7875
JAMA and Archives Journals
1-Mar-2005


Page: 1 2

Related medicine news :

1. Older doctors less likely to follow current standards of care
2. Older people get the big picture faster, and they are less inhibited
3. Older people with the Alzheimers gene find it harder to remember to remember even if healthy
4. Older patients with chronic kidney disease are costly as they transition to dialysis
5. Older patients less likely to receive care in the ICU
6. Older people recover from disabling events at higher rate than previously thought
7. Older people lose out all round in breast cancer treatment and care
8. Older patients need special attention in the dental chair
9. Older prostate cancer patients may face age bias
10. Older people and their homes
11. Older age of male partners makes young women more susceptible to HIV-1 infection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... ... November 13, 2018 , ... Today, MIT-born startup Atolla ... monthly subscription kit includes at home skin analysis tools for measuring oil, moisture, ... proprietary algorithm formulates the serum to combat a user’s specific skin issues (such ...
(Date:11/13/2018)... DIEGO (PRWEB) , ... November 13, 2018 , ... 2018 ... innovations in search results, there’s a lot for marketers to prepare for in the ... technology is the widespread adoption of AI. Most notably, AI is having a major ...
(Date:11/13/2018)... ... November 13, 2018 , ... RoosterBio ... and hMSC-specific bioprocess systems, announces today it has submitted a U.S. Food and ... cGMP hMSC working cell banks. This MF complements the MF for the CliniControl ...
(Date:11/13/2018)... (PRWEB) , ... November 13, 2018 , ... ... & Construction (EPC) company, announced that it has been named to Boston Business ... for the third consecutive year. This time, Beaumont Solar, through significant ...
(Date:11/13/2018)... ... November 13, 2018 , ... ... BTG has invested $20m in Veran Medical Technologies, Inc. and has an option ... healthcare company focused on Interventional Medicine. Their innovative medical technology helps physicians treat ...
Breaking Medicine News(10 mins):
(Date:11/13/2018)... ... November 13, 2018 , ... New Cleveland Clinic ... who have previously undergone weight-loss or bariatric surgery, and later suffer unrelated heart ... not have surgery, according to a new study from Cleveland Clinic researchers ...
(Date:11/13/2018)... ... November 13, 2018 , ... Society has always been told ... Unfortunately, regular chairs that maintain a 90-degree angle between the back and thighs do ... impossible to achieve correct spinal positioning when sitting in a typical chair — the ...
(Date:11/13/2018)... ... November 13, 2018 , ... The Healthcare Linen Alliance ... business development and partnerships. Rick has spent much of his career in the ... to Sales, Rick brings his extensive background in the industry to the team. ...
Breaking Medicine Technology:
Cached News: