HOME >> MEDICINE >> NEWS
Organ Transplants Helped By Donor Bone Marrow, University Of Pittsburgh Researchers Report At National Transplant Meetings

Children Receive Bone Marrow In Thymus In Unique Heart Transplant Study

CHICAGO, May 16 -- Providing patients with bone marrow from the same donor as the organ being transplanted significantly reduces rejection, especially if multiple doses of the donor bone marrow cells are given, according to results of a major, ongoing study at the University of Pittsburgh. In addition, preliminary results of the first-ever human trial involving children who received bone marrow injections into the thymus during heart transplantation indicate the procedure is both safe and feasible and has potential to promote long-term acceptance of the organ. Findings from both studies are being presented at the 18th Annual Scientific Meeting of the American Society of Transplantation May 15-19 and at the 25th Annual Scientific Meeting of the American Society of Transplant Surgeons May 19-21 in Chicago.

How to achieve long-term acceptance, or tolerance, of transplanted organs is a major area of study at the University of Pittsburgh. Much of the clinical research has evolved from the landmark observation by Thomas E. Starzl, M.D., Ph.D., that donor and recipient cells continue to coexist many years after transplantation. Dr. Starzl is professor of surgery and founder of the University of Pittsburgh's Thomas E. Starzl Transplantation Institute. For the past six years, UPMC researchers have been conducting a study -- the largest of its kind -- to determine if infusions of donor bone marrow at the time of transplant surgery can boost the cellular environment the team believes is necessary for tolerance.

Recently, the Pittsburgh team initiated a similar study with children undergoing heart transplantation. But instead of infusing bone marrow into the peripheral blood, researchers inject the bone marrow into the patient's thymus, where key cells of the immune system are educated to recognize self and non-self. This study represents the first human trial of its kin
'"/>

Contact: Lisa Rossi
rossiL@msx.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
17-May-1999


Page: 1 2 3 4

Related medicine news :

1. Organizational traits associated with quality patient care are essential to home care nursing
2. Roche pledges continued support for Organ Transplantation Research Foundation
3. Organ-transplant patients at particluar risk from low MMR vaccine uptake
4. Organ transplant recipients face serious kidney-failure risk, study finds
5. Organically grown foods higher in cancer-fighting chemicals than conventionally grown foods
6. National Conference on Organ Donation and Transplantation
7. Organised students are more successful
8. Organizations renew professionalism vows
9. U-M, World Health Organization host telemedicine symposium
10. Kidney Transplant Recipients Require Less Long-Term Care If They Receive Well-Matched Donor Organs
11. Therapy Developed At Cedars-Sinai Medical Center Shows Promise In Preventing Rejection Of Transplanted Organs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2018)... ... , ... Trees with fall colors are not a good sign in September. ... September. When a tree is under stress, its leaves will change color early as ... Giroud Tree and Lawn provides the top five Fall warning signs for trees ...
(Date:9/1/2018)... , ... August 31, 2018 , ... “Vitamin D is ... of Trivedi Effect, debuted as a hot new release in Vitamins and Supplements, Medical ... She is currently on a media tour around the United States. , With all ...
(Date:9/1/2018)... Texas (PRWEB) , ... September 01, 2018 , ... ... event proclaimed by the International Veterinary Academy of Pain Management (IVAPM) that aims ... Veterinary Medical Association (TVMA) is partnering with IVAPM by educating pet owners of ...
(Date:8/31/2018)... ... August 31, 2018 , ... Kessler Foundation, a ... of an MRI Simulator. In the MRI Simulator, the individual experiences the conditions ... this mock scan experience, research participants become accustomed to the sights and sounds ...
(Date:8/31/2018)... BEACH, Calif. (PRWEB) , ... August 31, 2018 , ... ... 2018 at SeaLegs at the Beach – an action sports gathering to celebrate the ... Circus Crew. The event raised money for Erik’s wife, Annika and their two small ...
Breaking Medicine News(10 mins):
(Date:9/15/2018)... ... September 14, 2018 , ... ... sequencing to enable greater library coverage. However, severe gaps and limitations associated ... remain. , Multiplexed phage display provides a simple, robust, and seamless high-throughput-ready ...
(Date:9/13/2018)... ... September 13, 2018 , ... Dr. Rod J. Rohrich is pleased to announce ... which draws rhinoplasty experts from around the world, will take place from March 22nd ... fundamentals of nasal anatomy to complex surgical procedures and detailed analysis of revision ...
(Date:9/12/2018)... ... September 12, 2018 , ... Patient experience ... as part of its Population Engage patient experience suite. Express Surveys are ... giving the provider organization a wealth of strategic and tactical knowledge in order ...
Breaking Medicine Technology:
Cached News: