Other highlights in the March 2 JNCI

ol of Public Health in Minneapolis, discusses two novel aspects of this study--comparing the offer of an explicit choice between screening tests to recommendations of a specific test and to the option of doing both tests, and comparing two methods of distributing the FOBT kits. He questions whether theoretical models of screening behavior would predict the surprising finding that subjects who were given a choice between screening methods did not have a higher screening participation rate than subjects who were not given a choice.


  • Article: Nereo Segnan, Centro Prevenzione Oncologica Regione Piemonte and Azienda Sanitaria Ospedaliera S Giovanni Battista, +390116333860, nereo.segnan@cpo.it
  • Editorial: Molly Portz, Media Relations, University of Minnesota, 612-625-2640, mportz@umn.edu

    Tamoxifen's Association With Endometrial Cancer Risk in Pre- and Postmenopausal Women Examined

    Tamoxifen use is associated with an increased risk of endometrial cancer. A new study has found that this risk is similar in pre- and postmenopausal women, increases with duration of use, and does not diminish through 5 years of follow-up after the treatment ends.

    Anthony J. Swerdlow, D.Sc., of the Institute of Cancer Research in Sutton, England, and colleagues conducted a casecontrol study in Britain of 813 patients who had endometrial cancer following breast cancer diagnosis and 1,067 control subjects who had breast cancer but not subsequent endometrial cancer.

    Overall, tamoxifen treatment was associated with 2.4 times the risk of endometrial cancer compared with no treatment. The risk increased with the duration of treatment and did not diminish in the 5 years following the end of treatment. The risk was similar in pre- and postmenopausal women. The authors write that, until further data are available, their results "suggest that the associated ris

  • Contact: Sarah L. Zielinski
    Journal of the National Cancer Institute

    Page: 1 2 3 4

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    2. Other highlights in the February 2 JNCI
    3. Other highlights in the January 19 JNCI
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