Other highlights of the M...( Selenium May Lower Risk of Esopha...)

Other highlights of the May 21 JNCI

Selenium May Lower Risk of Esophageal Cancer in People with Barrett's Esophagus: Higher serum selenium levels appear to be associated with a reduced risk of progression toward esophageal cancer among people with Barrett's esophagus, according to a new study. Rebecca E. Rudolph, M.D., of the Fred Hutchinson Cancer Research Center, Seattle, and her colleagues examined 399 people with Barrett's esophagus and found that people with higher concentrations of selenium in their blood were less likely to have increased 4N fraction, aneuploidy, and high-grade dysplasia-three markers of cancer progression. These individuals also were less likely to have lost the portion of chromosome 17 that contains the p53 tumor suppressor gene. The authors suggest that "selenium might reduce cancer risk among persons with Barrett's esophagus by preventing the inactivation of p53 or by preventing further neoplastic progression after p53 has been inactivated."
Contact: Kristen Woodward, Fred Hutchinson Cancer Research Center, 206-667-5095; kwoodwar@fhcrc.org.
Cyclin D1 May be Involved in Ovarian Cancer Growth: Researchers have found a second mechanism through which lysophosphatidic acid (LPA) may promote ovarian tumor growth. Yu-Long Hu, Ph.D., and Robert Jaffe, M.D., of the University of California, San Francisco, and their colleagues found that LPA treatment increases cyclin D1 protein levels in ovarian cancer cells but not in normal ovarian cells. Cyclin D1 is a key cell cycle regulator that is overexpressed in various human cancers, including ovarian cancer. A previous study found that LPA can stimulate ovarian cancer growth by increasing the expression of vascular endothelial growth factor (VEGF), which promotes angiogenesis (the formation of new blood vessels). The new findings suggest that LPA stimulates ovarian tumor growth through dual mechanisms. Finding ways to block these pathways may l
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(Date:11/21/2009)...oup merges their practice with that of E. Steven P... (PRWEB) November 21, 2009 -- The New Haven...son, Dr. Dean Cloutier, Dr. John Plachtyna and Dr....actice with that of esteemed colleague Dr. E. Stev... to retire from dentistry in order to concentrate ...

(Date:11/20/2009)...nderstanding Brain Wiring and Diseases ,, WASHI...my Schmahmann, Professor of Neurology at Harvard M... General Hospital in Boston, on Thursday, November...w field of study called "Connectivity" at the laun...n is an award-winning leader in the field of the c...

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(Date:11/20/2009).../ -- Following a recall by Unilever The Stop &...s Country Crock ® Side Dishes DELUXE Cheddar ...e Dishes DELUXE Four Cheese Pasta due to an undecl...ates and UPCs are affected: ,, Shedd,s Country...Rice 21 oz, UPC 027400218316, Best By NOV 29 09 th...

(Date:11/20/2009)...ire-FirstCall/ -- Rates of infection by the 2009 H...r, but the pandemic flu virus continues to be a po...ding the elderly, according to a new report by Que...rld,s leading provider of diagnostic testing, info...est Diagnostics Health Trends(TM) Report "Testing ...

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[0] New Haven Dental Group Expands Their Vision [0] MINDlink Foundation Launches to Connect the Cerebellum to Cures [0] Actuaries to Senate: Strengthen Individual Mandate [0] Stop & Shop Alerts Customers to Voluntary Recall by Unilever [0] H1N1 Pandemic May Have Peaked in October in U.S., According to Quest Diagnostics

(Date:11/19/2009)..., BIRMINGHAM, Ala., Nov. 19 /PRNewswire-FirstCall/...) today announced the pricing of a public offering...per share, resulting in gross proceeds of $48.75 m...oCryst pursuant to an effective shelf registration...d Exchange Commission. BioCryst has also granted ...

(Date:11/19/2009)..., TAINAN, Taiwan, Nov. 19 /PRNewswire-Asia/ --...harmaceutical ingredients (APIs), announced that i...d Safety Certification from,SafeBridge(R) Consulta...competency and proficiency in the safe handling of...and applies to specific laboratories and,productio...

(Date:11/19/2009)... ABBOTT PARK, Ill., Nov. 19 /PRNewswire-FirstCall/...: ABT ) as one of its Most Admired Corporate Dea...l honored Abbott as its Most Admired Dealmaker in...se of acquisitions and divestitures since January ...ped its business portfolio with a focus on high-gr...

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[0] BioCryst Announces Pricing of Public Offering of Common Stock [0] ScinoPharm Announces SafeBridge Potent Compound Safety Certification [0] The Deal Names Abbott Top Dealmaker for Second Consecutive Year

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Other highlights of the M...( Selenium May Lower Risk of Esopha...),Health