HOME >> MEDICINE >> NEWS
Ovarian tissue storage and later transplant shows promise for women infertile from cancer therapy

US researchers report promising findings of a technique which could potentially help women to regain fertility after early menopause due to cancer therapy. Results of the technique on a 30-year-old woman are reported in a fast-track study to be published online ahead of publication in the March 13 print issue of THE LANCET.

Cancer treatments such as chemotherapy, radiotherapy, and radical surgery can induce premature menopause and infertility in hundreds of thousands of women of reproductive age every year. One of the ways to possibly preserve fertility before these treatments is to freeze (cryopreserve) ovarian tissue for later transplantation.

Kutluk Oktay and colleagues from the Center for Reproductive Medicine and Infertility (CRMI) of NewYork-Presbyterian Hospital/Weill Cornell Medical Center, USA, cryopreserved ovarian tissue from a 30-year-old woman with breast cancer before chemotherapy-induced menopause. This tissue was transplanted beneath the skin of her abdomen 6 years later. The patient's ovarian function returned after three months, and in-vitro fertilisation resulted in the development of a four-cell embryo which was implanted into the woman, although she did not become pregnant.

Dr Oktay comments: "This research represents a potentially significant reproductive advancement in two respects: first, women can preserve their fertility by freezing their ovarian tissue, and second, pregnancy may be possible even after the tissue remains frozen for a long time." (quote by e-mail, does not appear in published paper)

In an accompanying Commentary, Johan Smitz from the Centre For Reproductive Medicine, University Hospital of the Vrije Universiteit Brussels, Belgium, cautions that cryopreservation and transplantation techniques for certain cancer cases are not without risk: "In light of the current uncertainty about the effectiveness and safety of ovarian cryostorage and grafting, the whole procedure should stil
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
8-Mar-2004


Page: 1 2

Related medicine news :

1. Ovarian cancer does have early warning signs, Mayo Clinic and Olmsted Medical Center find
2. Ovarian cancer rates across Europe
3. Ovarian carcinoma, ethnicity, and survival
4. Ovarian Hormone Could Play Key Role In Easier, Safer Childbirth
5. Medical molecules designed to respond to visible light that can penetrate tissue
6. Rice scientist recognized as pioneer in tissue engineering
7. How platelets help cancer invade other tissues
8. Long-term obesity linked to loss of brain tissue in women
9. Skeletal muscle cells could be source of stem cells for regenerating nerve tissue
10. Screening for virus RNA could increase safety of organ & tissue transplantation
11. Fetal tissue restores lost sight

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... 2017 , ... Global Lyme Alliance (GLA), the leading 501(c)(3) ... today announced the appointment of Timothy J. Sellati, Ph.D. as its Chief Scientific ... 20 years of research experience with Lyme and other tick-borne diseases. He has ...
(Date:9/21/2017)... ... September 21, 2017 , ... Process ... 1:30 p.m. – 3:00 p.m. ET, http://www.fdanews.com/processcapabilityindices      , ... wrong, run afoul of The Quality System Regulation (§820.250), and Devicemakers find themselves ...
(Date:9/21/2017)... ... September 21, 2017 , ... Promotional Communication:, Keeping Up ... , In the competitive world of drug and device marketing and promotion, drug ... FDA rules. , The FDA has issued two draft guidances that are the ...
(Date:9/21/2017)... ... , ... Bill Howe Plumbing’s mission is to create an employee friendly company, ... For over 37 years, they have operated with their mission at the foundation and ... Diego. They were chosen as the Best San Diego plumber in 2016, named a ...
(Date:9/21/2017)... ... September 21, 2017 , ... The New England Center for ... today the election of Yie-Hsin Hung to the Board of Directors. , “The ... of Directors. Ms. Hung is an invaluable addition to our team,” said Vincent Strully, ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
(Date:9/12/2017)... 2017  ValGenesis Inc., the global leader in ... to announce the appointment of Dr. Ajaz ... of Directors and Chairman of Advisory Board beginning ... companies to manage their entire validation lifecycle process ... this process. Furthermore, ValGenesis VLMS enables rigorous compliance, ...
(Date:9/7/2017)... Sept. 7, 2017  Eli Lilly and Company ... to streamline operations to more efficiently focus resources ... cost structure. Global workforce reductions, including those from ... to impact approximately 3,500 positions. ... annualized savings of approximately $500 million that will ...
Breaking Medicine Technology:
Cached News: