HOME >> MEDICINE >> NEWS
Overactive bladder episodes completely controlled in 40 percent of elderly patients treated with once-a-day Oxybutynin

Elderly patients suffering from overactive bladder can significantly and safely reduce the symptoms of their condition by taking a once-a-day, extended-release formulation of oxybutynin chloride (Ditropan XL®), according to a study conducted by the Cleveland Clinic Foundation scheduled for presentation at the 2000 Annual Scientific Meeting of the American Geriatrics Society.

In the study, 40 percent of patients age 65 and older taking extended-release oxybutynin reported no incontinence episodes, while the average reduction in the weekly number of incontinence episodes for the elderly patients in the study was 82 percent.

"We found that elderly patients not only benefit by significantly reducing or eliminating their incontinence episodes when taking the extended-release formulation of oxybutynin, they also can do so safely and tolerate the drug very well. This is good news for this patient population, which frequently must deal with taking multiple medications and experiencing worrisome side effects," said Rodney Appell, M.D., study author and head, Section of Voiding Dysfunction and Female Urology at the Cleveland Clinic Urological Institute.

Overactive bladder is a common and chronic condition that affects an estimated 17 million Americans. The condition is characterized by urge urinary incontinence (sudden and involuntary loss of bladder control resulting in wetting accidents), urgency (the urgent need to empty the bladder) and frequency (frequent urination). Ditropan XL is the first and only once-a-day treatment for overactive bladder approved by the FDA and is marketed by ALZA Corporation and UCB Pharma.

For the study, investigators analyzed three clinical trials comparing different doses of extended-release and immediate-release oxybutynin in 159 patients older than 65 and in 261 patients age 18 to 65. All of the 420 patients suffered from overactive bladder.

During the clinical trials, researchers adjusted the
'"/>

Contact: Jim Armstrong, Cleveland Clinic
216-444-9455
Porter Novelli
19-May-2000


Page: 1 2 3

Related medicine news :

1. Overactive bladder symptoms affect sexual activity of women says Univ. of Pittsburgh study
2. New substance that improves the photodetection of bladder cancer gains market approval
3. Study examines three-day antibiotic regimens for treating bladder infection in women
4. New study tests amitriptyline for painful bladder syndrome
5. New test improves detection of bladder cancer
6. Faster, less expensive test proven more effective in detecting bladder cancer
7. Promise of bladder pacemaker for people with spinal cord injury
8. Use of estrogen therapy may increase risk for gallbladder disease
9. FDA approves Enablex for treatment of overactive bladder
10. Long-term data show benefit of DETROL LA as first-line therapy for overactive bladder
11. Scientists begin validation study of test to detect recurrence of bladder cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... ... May 24, 2017 , ... ... CEO Mary Ellen, hospital employees, and town officials to celebrate the grand opening ... was developed by Rendina as part of its ongoing relationship with RWJBarnabas Health, ...
(Date:5/24/2017)... ... , ... Dr. Alan I. Benvenisty, MD is dual board certified in general ... for his distinguished expertise and experience in the diagnosis and treatment of vascular diseases. ... renovascular disease and aortic aneurysm . He is known for his minimally invasive ...
(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... ... innovative medical image management and interpretation, has received U.S. Food and Drug Administration ... Nucleus.io is a web-based, scalable and secure cloud platform for medical image management. ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Manju R. Kejriwal, a leading Ohio dentist, ... or without a referral. Dr. Kejriwal understands the emotional and financial toll traditional orthodontics ... Cincinnati, OH. Patients no longer need to feel the esthetic effects of wires and ...
(Date:5/24/2017)... , ... May 24, 2017 , ... ... Global Policy Solutions is vehemently opposed to Donald Trump’s budget, “A New Foundation ... despair that inspires fear, demonizes the poor, marginalizes underserved populations, undermines productivity, and ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Global Health Intelligence (GHI), the leading healthcare data analytics ... 2017 ranking of the Best-Equipped Hospitals in Latin America ... GHI,s hospitals database for Latin America , which is ... database covers 86% of the hospitals in Latin ... each institution in key areas such as beds, medical specialties, ...
(Date:5/9/2017)... , May 9, 2017  Demonstrating its ... board of directors for the Pharmaceutical Research and ... for membership. Biopharmaceutical companies will now have to ... order to be eligible to join PhRMA. ... the board is sending a clear message that ...
(Date:5/6/2017)... IRVING, Texas , May 5, 2017   Provista ... 1994 with more than 200,000 customers, today announced Jim ... brings a wealth of executive and business experience to Provista, ... a compounding pharmacy in California . He ... "Jim is a great fit for Provista," says ...
Breaking Medicine Technology:
Cached News: