HOME >> MEDICINE >> NEWS
PET scans identify breast-cancer patients who will respond to hormone therapy

St. Louis, June 11, 2001New research shows that PET scans can often identify which women with advanced breast cancer are likely to respond to hormone therapies such as tamoxifen.

Using PET scans, we were able to predict within two weeks who was responding to hormone therapy, said Joanne Mortimer, M.D., professor of medicine at Washington University School of Medicine. That is very significant. If doctors could tell within two weeks that someone will respond to hormone therapy, they will be less likely to prescribe chemotherapy for those patients.

The study, led by Mortimer, of the Siteman Cancer Center at Washington University and Barnes-Jewish Hospital, is published in the June 1 issue of the Journal of Clinical Oncology. Hormone therapy is kinder and gentler to patients than chemotherapy, and is usually just as effective. But according to Mortimer it is greatly under-used by physicians. Often, this is because the therapy initially produces symptoms of tumor growth, so doctors cant tell whether a woman is responding normally to the treatment or whether her cancer is progressing.

The problem occurs because hormone therapy stimulates breast tumors to flare up and grow a bit before causing them to shrink. This can result in pain at tumor sites and in elevated tumor markers in the blood. This flare reaction is physically experienced by about one in 20 women with advanced breast cancer who receive hormone therapy. At the same time, it is also known that women who experience a clinically detectable flare reaction respond to hormone therapy.

We proposed that all patients who eventually respond to hormone therapy have a temporary flare reaction, but that it occurs subclinically in most cases, said Mortimer. The researchers further proposed that this subclinical flare could be detected using positron emission tomography (PET). PET measures the functional activity of normal and diseased tissues in the body.

Mortimers study involved 40 women (av
'"/>

Contact: Darrell E. Ward
wardd@msnotes.wustl.edu
314-286-0141
Washington University School of Medicine
31-May-2001


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... The Radiology Business Management Association (RBMA) ... annual awards, now in their 12th year, are among the most prestigious in radiology ... 2016, the awards were retooled to recognize achievements in both large budget (over $5,000) ...
(Date:3/24/2017)... Arizona (PRWEB) , ... March 24, 2017 , ... ... Healing Center, Sedona, Arizona’s Premier Center for Shamanic Healing and Spiritual Awakening, ... Luis Delgado, June 9--24, 2017. This sacred and spiritual journey during the ...
(Date:3/24/2017)... ... ... The law firm of Enea, Scanlan & Sirignano, LLP, with ... C. Enea has joined the firm as an associate attorney. Ms. Enea, who previously ... law, Medicaid planning and applications, and Wills, Trusts and Estates. Samantha A. Lyons, ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Finding Christ Through Social ... devotional journal chronicling the writer’s path toward true communion with God. “Finding Christ ... #TruthwithGrace” is the creation of published author Lea Michelle Johnson, a follower of ...
(Date:3/23/2017)... ... March 23, 2017 , ... In 2016 the World Health Organization ... could be four million Zika-related cases in the Americas within the next year. Lyme ... cases reported per year skyrocketing to an estimated 329,000. Yet, Zika, Lyme and other ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... YORK , March 24, 2017 ... ... a leading publisher of cannabis market research, the legal cannabis ... percent CAGR through 2021, despite conflicting signals from the current ... points out that the two biggest drivers of growth in ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... report to their offering. ... The Deep Learning: Drug Discovery and Diagnostics Market, 2017-2035 ... market of deep learning solutions within the healthcare domain. Primarily driven ... a novel solution to generate relevant insights from medical data. ...
(Date:3/24/2017)... -- Today Stock-Callers.com have issued research reports on ... (NASDAQ: NVCN), Hologic Inc. (NASDAQ: HOLX), Edwards Lifesciences Corp. (NYSE: ... These companies are part of the Healthcare sector, which gave ... rd , 2017, with the NYSE Health Care Index declining ... in the S&P 500 were down about 0.4% as a ...
Breaking Medicine Technology:
Cached News: