HOME >> MEDICINE >> NEWS
PET scans identify breast-cancer patients who will respond to hormone therapy

St. Louis, June 11, 2001New research shows that PET scans can often identify which women with advanced breast cancer are likely to respond to hormone therapies such as tamoxifen.

Using PET scans, we were able to predict within two weeks who was responding to hormone therapy, said Joanne Mortimer, M.D., professor of medicine at Washington University School of Medicine. That is very significant. If doctors could tell within two weeks that someone will respond to hormone therapy, they will be less likely to prescribe chemotherapy for those patients.

The study, led by Mortimer, of the Siteman Cancer Center at Washington University and Barnes-Jewish Hospital, is published in the June 1 issue of the Journal of Clinical Oncology. Hormone therapy is kinder and gentler to patients than chemotherapy, and is usually just as effective. But according to Mortimer it is greatly under-used by physicians. Often, this is because the therapy initially produces symptoms of tumor growth, so doctors cant tell whether a woman is responding normally to the treatment or whether her cancer is progressing.

The problem occurs because hormone therapy stimulates breast tumors to flare up and grow a bit before causing them to shrink. This can result in pain at tumor sites and in elevated tumor markers in the blood. This flare reaction is physically experienced by about one in 20 women with advanced breast cancer who receive hormone therapy. At the same time, it is also known that women who experience a clinically detectable flare reaction respond to hormone therapy.

We proposed that all patients who eventually respond to hormone therapy have a temporary flare reaction, but that it occurs subclinically in most cases, said Mortimer. The researchers further proposed that this subclinical flare could be detected using positron emission tomography (PET). PET measures the functional activity of normal and diseased tissues in the body.

Mortimers study involved 40 women (av
'"/>

Contact: Darrell E. Ward
wardd@msnotes.wustl.edu
314-286-0141
Washington University School of Medicine
31-May-2001


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
Breaking Medicine Technology:
Cached News: