HOME >> MEDICINE >> NEWS
PET scans identify breast-cancer patients who will respond to hormone therapy

St. Louis, June 11, 2001New research shows that PET scans can often identify which women with advanced breast cancer are likely to respond to hormone therapies such as tamoxifen.

Using PET scans, we were able to predict within two weeks who was responding to hormone therapy, said Joanne Mortimer, M.D., professor of medicine at Washington University School of Medicine. That is very significant. If doctors could tell within two weeks that someone will respond to hormone therapy, they will be less likely to prescribe chemotherapy for those patients.

The study, led by Mortimer, of the Siteman Cancer Center at Washington University and Barnes-Jewish Hospital, is published in the June 1 issue of the Journal of Clinical Oncology. Hormone therapy is kinder and gentler to patients than chemotherapy, and is usually just as effective. But according to Mortimer it is greatly under-used by physicians. Often, this is because the therapy initially produces symptoms of tumor growth, so doctors cant tell whether a woman is responding normally to the treatment or whether her cancer is progressing.

The problem occurs because hormone therapy stimulates breast tumors to flare up and grow a bit before causing them to shrink. This can result in pain at tumor sites and in elevated tumor markers in the blood. This flare reaction is physically experienced by about one in 20 women with advanced breast cancer who receive hormone therapy. At the same time, it is also known that women who experience a clinically detectable flare reaction respond to hormone therapy.

We proposed that all patients who eventually respond to hormone therapy have a temporary flare reaction, but that it occurs subclinically in most cases, said Mortimer. The researchers further proposed that this subclinical flare could be detected using positron emission tomography (PET). PET measures the functional activity of normal and diseased tissues in the body.

Mortimers study involved 40 women (av
'"/>

Contact: Darrell E. Ward
wardd@msnotes.wustl.edu
314-286-0141
Washington University School of Medicine
31-May-2001


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... February 05, 2016 , ... Steven Tonkinson, 36, of Coconut Grove, ... year since it started in 2003. This year, he ran all 26.2 miles with ... and NBA team the Miami Heat. , This Sunday, while many are watching the ...
(Date:2/5/2016)... Falls, NY & Salt Lake City, UT (PRWEB) , ... February ... ... Davis, Founder of Activz Whole-Food Nutrition , announced that the much-anticipated feature with ... on the New Really Cool Humans Amateur TV Network. , Each week, on his ...
(Date:2/5/2016)... ... 2016 , ... The Muscular Dystrophy Association and Sailormen Inc., ... 14th annual “Appetite for a Cure” campaign on Feb. 1 to raise critical ... diseases that severely limit strength and mobility. , Now through March 20, ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... President George H. Van Allen have signed a joint enrollment and degree completion ... seamless pathway toward associate and baccalaureate degrees at FHU|Dickson. , The agreement ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... US ... Yoga Studio in Dover, NH to direct high-performance kids yoga training. ChildLight Yoga Studio ... seacoast, just one hour from Boston. , ChildLight Yoga Studio founder Lisa Flynn expresses ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... -- Patients in Alabama seeking prostate care ... longer have to travel out of state. Vituro Health ... Centers of Alabama to provide a total prostate management ... Alabama is known throughout ... cancer using many different modalities. They are the largest and ...
(Date:2/5/2016)... Aethlon Medical, Inc. (Nasdaq: AEMD ), today ... be presenting at Source Capital Group,s 2016 Disruptive Growth & ... at 2:15 p.m. ET on Wednesday, February 10, 2016.  Mr. ... place at 3:15 p.m. ET. http://www.aethlonmedical.com .  The ... the conclusion of the live event. The panel discussion will ...
(Date:2/5/2016)... 5, 2016 Dehaier Medical Systems Ltd. ... "Company"), which develops, markets and sells medical devices ... China and international markets, today announced ... to concentrate the Company,s resources to develop its ... and to focus more on its major businesses. ...
Breaking Medicine Technology:
Cached News: