HOME >> MEDICINE >> NEWS
PET scans identify breast-cancer patients who will respond to hormone therapy

St. Louis, June 11, 2001New research shows that PET scans can often identify which women with advanced breast cancer are likely to respond to hormone therapies such as tamoxifen.

Using PET scans, we were able to predict within two weeks who was responding to hormone therapy, said Joanne Mortimer, M.D., professor of medicine at Washington University School of Medicine. That is very significant. If doctors could tell within two weeks that someone will respond to hormone therapy, they will be less likely to prescribe chemotherapy for those patients.

The study, led by Mortimer, of the Siteman Cancer Center at Washington University and Barnes-Jewish Hospital, is published in the June 1 issue of the Journal of Clinical Oncology. Hormone therapy is kinder and gentler to patients than chemotherapy, and is usually just as effective. But according to Mortimer it is greatly under-used by physicians. Often, this is because the therapy initially produces symptoms of tumor growth, so doctors cant tell whether a woman is responding normally to the treatment or whether her cancer is progressing.

The problem occurs because hormone therapy stimulates breast tumors to flare up and grow a bit before causing them to shrink. This can result in pain at tumor sites and in elevated tumor markers in the blood. This flare reaction is physically experienced by about one in 20 women with advanced breast cancer who receive hormone therapy. At the same time, it is also known that women who experience a clinically detectable flare reaction respond to hormone therapy.

We proposed that all patients who eventually respond to hormone therapy have a temporary flare reaction, but that it occurs subclinically in most cases, said Mortimer. The researchers further proposed that this subclinical flare could be detected using positron emission tomography (PET). PET measures the functional activity of normal and diseased tissues in the body.

Mortimers study involved 40 women (av
'"/>

Contact: Darrell E. Ward
wardd@msnotes.wustl.edu
314-286-0141
Washington University School of Medicine
31-May-2001


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... ... May 03, 2016 , ... ... creative director Joe Ferrazano to serve in the newly created position of executive ... overseeing the agency’s creative efforts in the Chicago and LA offices. He reports ...
(Date:5/3/2016)... CA (PRWEB) , ... May 03, 2016 , ... ... accredited American online university, has announced today the launch of its Associates and ... Laureate and President Emeritus of The Rockefeller University, Dr. Torsten N. Wiesel; Chairman ...
(Date:5/3/2016)... Toledo, OH (PRWEB) , ... May 03, 2016 , ... ... remain a leading cause of death across the United States and account for one ... physical and mental impairments or are permanently disabled. HCR ManorCare is launching a video ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... Canada’s top Information and Communication Technology (ICT) companies in the annual Branham300 listing. ... companies operating in Canada, as ranked by revenue. , “We are honored ...
(Date:5/3/2016)... Miami, FL (PRWEB) , ... May 03, 2016 , ... ... support both its Grow & Climb children and youth programs in South Miami. Macy’s ... several years. , The Grow Program provides afterschool tutoring, mentoring, enrichment and academic ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... April 29, 2016  In the next ten ... shift from systems dependent on CRTs monitors to those ... modality CRT Medical monitors and will automatically sync ... host of foreseeable benefits to this technological advancement, ... modalities have to be replaced in order to ...
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology ... appointment of Dr. Alfredo Zurlo as Chief ... with many years clinical experience and a proven track ... role was at Mologen AG where he was Chief ... Dr. Zurlo held various positions at F Hoffmann La ...
(Date:4/28/2016)... April 28, 2016 Research and ... Plastic Surgery Products Market 2016-2020" report to their ... , The global plastic surgery products market ... during the period 2016-2020. , ,The growing adoption of ... the growth of the market. Lasers are used to ...
Breaking Medicine Technology:
Cached News: