Panel: Clinical use of embryonic stem cells jeopardized by Bush's policy on federal funding

The human embryonic stem cell lines currently eligible for research with federal funds are not suitable for use in future clinical trials, nor would they ensure fair access to new stem cell-based therapies, according to the scientists, philosophers and lawyers on a panel convened at Johns Hopkins.

The federally approved human embryonic stem (ES) cell lines were initially grown on mouse cells and therefore might harbor mouse-specific viruses. Ethically and scientifically, potentially exposing study participants to a mouse virus -- which people's immune systems might be unable to combat -- is not a risk worth taking in the face of safer alternatives, the panel unanimously agreed.

"Conducting a federally funded clinical trial of human ES cells, under current federal policy, would require using cell lines that none of us feel should be used in people, since it is now feasible to create safer lines," says Ruth Faden, Ph.D., M.P.H., a leader of the panel and executive director of the Phoebe R. Berman Bioethics Institute at Johns Hopkins. "So, all clinical trials -- and by extension the experiments leading to them -- should be conducted with newer cell lines not eligible for federal funding. The likelihood of getting to a clinical trial using only private funds, however, is very slim.

"Moreover," she adds, "the absence of federal funding would mean a reduced role for federal oversight of the ethics of human embryonic stem cell research."

By contrast, the Food and Drug Administration has said that growth of human ES cells on mouse cells need not be a sticking point for clinical research. Instead, they say the ES cells would then merely fall under guidelines for so-called xenotransplantation, or cross-species transplantation.

"But techniques now exist to create and maintain human embryonic stem cell lines without using mouse cells, and such cell lines already exist, so t

Contact: Joanna Downer
Johns Hopkins Medical Institutions

Page: 1 2 3 4 5 6

Related medicine news :

1. Clinical breast examination offers modest benefit to breast cancer screening program
2. Clinical trial of Etanercept for Wegeners disease shows no benefit
3. Clinical trial participants fare no better, no worse than other patients
4. Clinical trial shows drug may offer a new option to prevent rejection of transplanted kidneys
5. National Academies news: Clinical research involving children
6. Clinical research key in advance to prospective health care
7. Clinical trial of new TB vaccine begins
8. Clinical trial of Alzheimers disease drug shows clear reductions in AD development
9. Clinical factors useful to identify heart failure patients with high risk of death
10. $7 million grant continues Asthma Clinical Research Network efforts
11. Clinical study of Penn State Hershey technology begins in South Africa

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: