Several vaccines for the prevention of sexually transmitted infections (STIs) are in development, according to background information in the article. Because an ideal STI immunization program would target young adolescents and preadolescents before they become sexually active, much of the decision-making burden would be placed on parents. It has been suggested that pediatricians may be reluctant to recommend STI vaccination in anticipation of negative parental reactions.

Gregory D. Zimet, Ph.D., from Indiana University School of Medicine, Indianapolis, and his colleagues analyzed the responses of 278 parents to questionnaires to evaluate how their willingness to vaccinate their children related to four possible variables: mode of transmission, whether the infection was sexually transmitted or not; severity of the infection, whether the infection was curable, chronic or fatal; vaccine efficacy, 50, 70 or 90 percent effective; and whether or not a behavioral method for prevention was available (for example, hand washing or condom use).

Parents were as willing to vaccinate their children against STIs as other types of infection (81.3 versus 80.0 on the study's rating scale), the researchers found. The most important determinants for parents in making their decision were the severity of the infection and the vaccine's effectiveness. Parents favored vaccines for infections that had no methods of behavioral prevention available.

"Most parents are focused on protecting their children's health and not so concerned about the source of infection," the authors concluded. "Clearly, the severity of disease and the efficacy of the vacc
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Contact: Mary Hardin
317-274-7722
JAMA and Archives Journals
7-Feb-2005