There are currently two sites in each hemisphere of the brain where stimulation is targeted. In the same study, researchers found no significant difference in motor performance between two groups of patients who received stimulation at either site. But given past evidence that patients who receive stimulation at one of the sites may be more prone to depression and other neuropsychological conditions, the study's authors conclude the current bias toward placing the implants on that site may be unwarranted.
"These data clearly indicate that unilateral deep brain stimulation improves bilateral motor performance of the arms and hands," said Jay Alberts, an assistant professor in the School of Applied Physiology at the Georgia Institute of Technology.
Alberts, along with researchers from Emory University and the University of Florida, collaborated on a study in which 10 patients with advanced Parkinson's disease participated in a series of tests designed to measure upper body motor performance. The tests were designed to mimic everyday activities that Parkinson's patients often have trouble with, such as opening jars or tying shoelaces. The patients performed the tests while the stimulator was on and then three hours after it was turned off.
Deep brain stimulation works by using
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Contact: David Terraso
david.terraso@icpa.gatech.edu
404-385-2966
Georgia Institute of Technology
21-Oct-2004