Patient with drug-resistant form of HIV identified

Researchers have identified a patient with a unique variant of HIV that is resistant to multiple classes of antiretroviral drugs and associated with the rapid development of AIDS, reporting their findings in this week's issue of THE LANCET.

The patient is a New York man who had unprotected sex with multiple partners and regularly took the illegal stimulant metamfetamine. His infection with HIV resulted in progression to symptomatic AIDS in 4-20 months. Martin Markowitz (Aaron Diamond AIDS Research Centre, New York, USA) and colleagues analysed the genetic make-up of the patient's virus and assessed its susceptibility to antiretroviral drugs.

Rapid progression to AIDS after infection with HIV-1 has been previously described, as has the transmission of multidrug resistant viruses. However, the unique feature of this report is the combination of these two features multidrug resistance and rapid clinical course to AIDS.

Previous research suggests that the likelihood to progression to AIDS in 6 and 12 months is seven per 10,00 and 45 per 10,000 individuals respectively. The cause of the rapid disease progression may be due to a particularly aggressive form of HIV. However, studies looking into this are ongoing and currently incomplete. The authors note that the public health ramifications of this case are great since the patient reported having unprotected sex with multiple partners.

Dr Markowitz states: "Only additional investigations will reveal whether this case is isolated or not. Irrespective of the outcome, efforts to prevent HIV-1 transmission need to be intensified, with particular emphasis on the epidemic that is being propelled by the use of metamfetamine. However, in doing so, care should be taken to avoid punitive measures against the populations most vulnerable to HIV-1."

In an accompanying editorial The Lancet comments: "This case serves as a reminder that HIV remains a frighteningly versatile foe, one that can muta

Contact: Joe Santangelo

Page: 1 2

Related medicine news :

1. Patients newly diagnosed with HIV are more likely to enter outpatient care with case management
2. Patient knows best when it comes to ulcerative colitis, U-M study finds
3. Patients with cancer have highly increased risk for blood clots
4. Patients with previous heart attacks may not benefit from pacemaker implant
5. Patients with cancer detected on screening mammography undergo less toxic treatment
6. Patient protection laws dont favor health providers
7. Patients with moderate or severe hand dermatitis responsive to drug therapy
8. Patients with abdominal trauma at risk for intra-abdominal infections following surgery
9. Patients who are intubated prior to hospital arrival fare worse find Pitt researchers
10. Patients undergoing weight loss surgery have high rates of H pylori bacteria
11. Patients with chronic sinus do not necessarily develop antibiotic resistance

Post Your Comments:

(Date:8/28/2020)... ... August 28, 2020 , ... ... CEO Craig Mandeville was named an Entrepreneur Of The Year® 2020 Florida Award ... entrepreneurial business leaders whose ambitions deliver innovation, growth and prosperity as they build ...
(Date:8/28/2020)... ... August 28, 2020 , ... The ... a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV received a ... Solutions Foundation awards grants each year to organizations, such as Destination Imagination, which ...
(Date:8/28/2020)... ... 28, 2020 , ... Integrated Viral Protection (IVP Air) today announced ... deploy its breakthrough Mobile Biodefense Indoor Air Protection System that is the first system ... to fully reopen equipped with the filtration system on September 8th. , The ...
(Date:8/28/2020)... ... 2020 , ... A July 27 article on ... an increased risk of developing severe COVID-19 symptoms. The article does not suggest ... same organ systems that the coronavirus attacks are already suffering from the adverse ...
(Date:8/27/2020)... ... August 27, 2020 , ... The ... a leading aesthetic and wellness retreat. The practice is centered on results and ... Las Vegas. , Designed to be a sanctuary for total body renewal ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... 28, 2020 , ... Cano Health, LLC, a leading population ... San Antonio is happy to announce that it has selected Tejano musician Jay ... he will serve as community advisor, advertising talent, and creative consultant for Cano ...
(Date:8/28/2020)... ... August 28, 2020 , ... Dr. Raheleh Sarbaziha has been ... and approach. Armed with her qualifications from Ross University School of Medicine and ... the human body with the nation and world. With a fellowship in Integrative ...
(Date:8/27/2020)... (PRWEB) , ... August 27, 2020 , ... Austin Oral ... – is pleased to announce Dr. David Szalay, DDS, MD, has joined the practice. ... patients in the new Pflugerville office, which is scheduled to open this fall. The ...
Breaking Medicine Technology:
Cached News: