HOME >> MEDICINE >> NEWS
Patients with cancer have highly increased risk for blood clots

ation who also had cancer had a 12-fold increased risk vs. individuals without cancer and factor V Leiden. Similar results were indirectly calculated for the prothrombin 20210A mutation in patients with cancer.

"Assuming a baseline risk of 1 to 4 patients with venous thrombosis per 1,000 per year, a 5 percent prevalence of factor V Leiden and a 2 percent prevalence of the prothrombin 20210A mutation, among 10,000 patients with cancer, we would expect 8 to 34 patients with venous thrombosis due to factor V Leiden or the prothrombin 20210A mutation. Screening for factor V Leiden and the prothrombin 20210A mutation and subsequent prophylactic anticoagulant therapy with an effectivity of 80 percent would prevent annually 7 to 27 venous thrombotic events per 10,000 patients with cancer screened (numbers needed to screen: 700-2,700), which does not make screening a useful strategy. Rather than screening for factor V Leiden or the prothrombin 20210A mutation, it may be more cost-effective to consider prophylactic anticoagulant therapy for patients with cancer who have an increased risk to develop venous thrombosis," the authors conclude.
(JAMA. 2005;293:715-722. Available post-embargo at JAMA.com)

Editor's Note: This research was supported by grants from the Netherlands Heart Foundation and from the Dutch Cancer Foundation.


'"/>

Contact: Frits R. Rosendaal, M.D., Ph.D.
f.r.rosendaal@lumc.nl
JAMA and Archives Journals
8-Feb-2005


Page: 1 2

Related medicine news :

1. Patients newly diagnosed with HIV are more likely to enter outpatient care with case management
2. Patients with previous heart attacks may not benefit from pacemaker implant
3. Patients with cancer detected on screening mammography undergo less toxic treatment
4. Patients with moderate or severe hand dermatitis responsive to drug therapy
5. Patients with abdominal trauma at risk for intra-abdominal infections following surgery
6. Patients who are intubated prior to hospital arrival fare worse find Pitt researchers
7. Patients undergoing weight loss surgery have high rates of H pylori bacteria
8. Patients with chronic sinus do not necessarily develop antibiotic resistance
9. Plastic surgeons honor Patients of Courage overcoming difficult obstacles, inspiring others
10. Patients with severe depression improve using guidelines developed by UT Southwestern researchers
11. Patients not sticking to cholesterol drugs -- and the higher their co-pay, the lower their use

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2019)... ... June 24, 2019 , ... innovaTel Telepsychiatry, a ... restructuring of the Strategic Advisory Board (SAB) to help inform the Company’s efforts ... health care. , We are honored to announce that Linda Rosenberg, ...
(Date:6/20/2019)... ... June 20, 2019 , ... Access Healthcare, ... announced that Angel Rosa has been appointed as Senior Vice President of Client ... implementing new services, growing and nurturing high performing teams, and driving revenue growth ...
(Date:6/20/2019)... , ... June 20, 2019 , ... The 2019 Colorado ... with five international and four top-20 UCI women’s elite teams, organizers announced today. ... Twenty20, also will be coming to the race. , The standalone pro women’s ...
(Date:6/19/2019)... ... June 19, 2019 , ... CEO Steven C. Bilt of Smile Brands Inc. ... . Glassdoor , one of the world’s largest job and recruiting sites, ... working for in countries throughout North America and parts of Europe. , Smile Brands, ...
(Date:6/19/2019)... Mass. (PRWEB) , ... June 19, 2019 , ... ... 26th annual International Research Congress (IRC) in Marseille, France. The conference ... of state-of-the-art research on facioscapulohumeral muscular dystrophy (FSHD). Nearly 200 researchers, clinicians, industry ...
Breaking Medicine News(10 mins):
(Date:6/24/2019)... ... June 24, 2019 , ... Enespro PPE , ... comfort for the electrical industry has today announced the release of its guide ... guide, titled Developing a Culture of Electrical Safety, is written to address the ...
(Date:6/20/2019)... (PRWEB) , ... June 20, 2019 , ... ... and risk in clinical trials, today announced its scientific and technological experts will ... 2019 Drug Information Association (DIA) Annual Meeting in San Diego, June ...
(Date:6/19/2019)... ... June 19, 2019 , ... Advocates for ... of social welfare and protection of physicians’ rights, asserts that the recent SB ... and still rely on narrow guidelines as a basis for issuing legitimate medical ...
Breaking Medicine Technology:
Cached News: