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Penn finds atrial fibrilation cure eliminates need for pacemakers, medicine

Cardiac Rhythm Specialists for the University of Pennsylvania Health System have documented the effectiveness of a new technique to cure atrial fibrillation (A-Fib). The technique targets and isolates the triggers, or "hot spots," on pulmonary veins leading to the heart, preserving the heart's natural electrical circuitry and eliminating the need for a pacemaker or medication.

Francis E. Marchlinski, MD, director of Cardiac Electrophysiology for the University of Pennsylvania Health System, discusses the findings at an 8:30 a.m. session today (Wednesday) of the American College of Cardiologists meeting in Atlanta.

"This procedure can eliminate atrial fibrillation completely and patients can resume their lives without relying on mechanical devices or any form of medication, including blood-thinners," Marchlinski says.

Atrial fibrillation is a serious condition, often associated with aging, which results when electrical discharges in one of the atria (upper chambers of the heart) disrupts the normal, organized electrical activity, or "sinus rhythm," generated by the heart's sinus node.

Patients with this arrhythmia often suffer a rapid heartbeat, palpitations, weakness, shortness of breath and fatigue, although sometimes the condition manifests no symptoms. The arrhythmia may begin with occasional or regular bouts of an irregular heart beat, but it generally worsens over the years.

Traditional ablation procedures for this arrhythmia deliver an electrical charge that permanently blocks the electrical connection that transmits the impulse from the atria to the heart's lower ventricles. A pacemaker is then required to maintain an adequate heart rate. The older procedure does not cure afibrillation but merely prevents the fast heart rate that frequently accompanies atrial fibrillation, and patients still require blood-thinning medication.

The Penn procedure is more specific in targeting the triggers for atrial fibrillation, rat
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Contact: Ellen O'Brien
ellen.obrien@uphs.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
20-Mar-2002


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