SAN FRANCISCO People who previously were not considered good candidates for LASIK because of large pupils can now get the procedure, according to a study appearing in the July issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association. By using a larger laser treatment zone on the underlying layers of the cornea, surgeons can avoid inducing night vision disturbances such as haloes and glare that patients with large pupils often experience.

In this study, the first to evaluate laser treatment zones larger than 6.5 millimeters, 352 eyes of 186 patients underwent LASIK for correction of nearsightedness and nearsightedness with astigmatism. The treatment zones varied from six to eight millimeters, depending on the size of the patient's pupil, degree of astigmatism and amount of needed correction.

Among patients with nearsightedness, nearly 56 percent achieved uncorrected visual acuity of 20/20 or better; among those with nearsightedness with astigmatism, nearly 62 percent achieved 20/20 or better. In addition, preoperative best-corrected visual acuity and best spectacle-corrected contrast sensitivity were maintained.

Brian S. Boxer Wachler, MD, co-author of the study and a faculty member at the UCLA Medical Center, Jules Stein Eye Institute, said, "We know that corneal aberrations and night vision disturbances after LASIK are directly proportional to the degree of nearsightedness corrected and the size of the clearance zone that is, the difference between pupil size and the optical zone treated by the laser. With this study, we now know use of large optical zones is safe and effective in preventing nighttime glare and haloes in patients with large pupils."

"This study shows using ablation zones from six to eight millimeters did not pose a problem in terms of safety. If anything, the larger optical zones had a higher percentage of eyes achieving 20/20 and 20/40 uncorrected visual acuity than th
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Contact: Media Relations
pgreene@aao.org
415-561-8534
American Academy of Ophthalmology
24-Jul-2003

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