HOME >> MEDICINE >> NEWS
Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant

The degree to which a person is easy-going or irritable--a personality trait thought to be one of the stable touchstones of identity--can be shifted more toward the easy-going side by a drug used to treat depression, University of California San Francisco researchers report.

The evidence that drugs can act on the brain to change once-stable measures of personality is published in the March issue of the American Journal of Psychiatry by a UCSF research team led by Victor Reus, MD, and Owen Wolkowitz, MD, professors of psychiatry at UCSF, and by postdoctoral fellow Brian Knutson, PhD.

Twenty-three mentally healthy men and women, average age 27, who took the anti-depressant paroxetine for four weeks as part of the study scored lower on survey questionnaires used to measure hostility and exhibited more engaging and cooperative behavior in puzzle-solving tasks with a partner than they did at the beginning of the study.

In comparison, a matching group of study volunteers who took only an inactive placebo pill did not change by these measures.

"Personality, a set of traits and attributes that characterize individuals and that persist throughout life, has been thought to be about fifty to sixty percent attributable to inheritance, a conclusion based in large part on studies of twins reared either together or apart," Reus explains.

"Inherited aspects of personality by definition must have some biological underpinning, but this is the first controlled study of the effects of a drug on a component of personality in people who are not mentally ill," he says. "Our findings lead us to conclude that different aspects of normal personality may be altered by psychopharmaceuticals that act on distinct nerve pathways in the brain."

Other researchers in previous studies found that, in psychiatric patients, low levels of a signaling molecule, the neurotransmitter serotonin, may be related to psychiatric disorders characterized by hostility and aggression, Reus
'"/>

Contact: UCSF News Services
415-476-2557
University of California - San Francisco
1-Mar-1998


Page: 1 2 3

Related medicine news :

1. Thought for food
2. Common Drug-Capsule Coating Not As Inert As Previously Thought
3. Mayo Clinic Cardiologist Available To Discuss New Guidelines On Treatment Of Stable Angina
4. Time, trust key to successful teen-doctor relationship
5. Bone Cement Used In Total Hip Replacements Slowly Degrades In Body Over Time, According To UCSF Study
6. Changes in ovaries could indicate higher risk of ovarian cancer
7. Changes needed to reduce migrant farm worker exposure to pesticides
8. Changes in allied and auxiliary health care workers training needed for quality of patient care, according to UCSF report
9. American Heart Association Comment: Contributions Of Trends In Survival And Coronary-Event Rates To Changes In Coronary Heart Disease Mortality
10. Psychologist Detects Brain-Activity Changes In Maltreated Kids
11. Changes In Levels Of LDLc From Pre- To Post-Menopausal Years Not Valuable Indicator Of Heart Disease, Reports University Of Pittsburgh Researcher

Post Your Comments:
(Date:7/3/2015)... , ... July 03, 2015 , ... ... Friend opened registration for a new SEO training system called "Page One ... for organic traffic generation has received glowing reviews from several well-known marketers. HonestyFirstReviews.com's ...
(Date:7/3/2015)... ... ... Renowned rhinoplasty surgeon and Symposium Chairman, Dr. Rod J. Rohrich , ... held from March 4th - 6th, the 2016 (a previous announcement had stated the ... to take participants from the basic training and fundamentals of nasal surgery through the ...
(Date:7/3/2015)... ... July 03, 2015 , ... The Erie County Bar Association ... 1:00pm. The Association welcomed speaker C. Daniel McGillicuddy Esq. of William Mattar Law ... of investigating these types of cases. , Each year, New York State residents ...
(Date:7/3/2015)... , ... July 03, 2015 , ... Jennifer Renee Hanes, ... Choice Emergency Room , the largest network of independent freestanding emergency rooms in the ... medical director of our Sienna Plantation facility,” said Executive Medical Director of First Choice ...
(Date:7/3/2015)... ... July 03, 2015 , ... Yisrayl Hawkins, Pastor and Overseer ... week that he says will reveal biblical truth and expose popular lies regarding proper ... Bible Say Don’t Have Sex”, immediately goes into the core of the subject by ...
Breaking Medicine News(10 mins):Health News:Page One Engine - Review Of Dori Friend's SEO Training Course Released 2Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 3Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3Health News:Yisrayl Hawkins Explains What the Bible Really Says about Sex in New Publication This Week 2
(Date:7/3/2015)... YORK , July 3, 2015  Obsidian HDS, ... - an online service for the management of data ... announced today that PharmaShine now includes the 2014 Open ... for Medicare Services on June 30. The data disclosed ... million transactions between industry and providers totaling $6.49 billion ...
(Date:7/2/2015)... Pharma Major Lupin Limited ... en ZAO "Biocom" en Rusia bajo ciertas condiciones ... Lupin en el mercado farmacéutico de Rusia que ... como uno de los 10 principales mercados farmacéuticos ... de una década, el mercado farmacéutico ruso registró ...
(Date:7/2/2015)... , July 2, 2015 Leading ... to capture critical product and market insights in ... benefits to employee-based studies, it is essential for ... own internal employees to capture critical business-related insights. ... benchmarking firm, Best Practices, LLC, most benchmarked companies ...
Breaking Medicine Technology:New Open Payments (Sunshine Act) Data Now Searchable on PharmaShine 2Lupin adquiere Biocom en Rusia 2Lupin adquiere Biocom en Rusia 3Leveraging Employee Insights to Produce Cutting-Edge Market Research 2
Cached News: