HOME >> MEDICINE >> NEWS
Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant

The degree to which a person is easy-going or irritable--a personality trait thought to be one of the stable touchstones of identity--can be shifted more toward the easy-going side by a drug used to treat depression, University of California San Francisco researchers report.

The evidence that drugs can act on the brain to change once-stable measures of personality is published in the March issue of the American Journal of Psychiatry by a UCSF research team led by Victor Reus, MD, and Owen Wolkowitz, MD, professors of psychiatry at UCSF, and by postdoctoral fellow Brian Knutson, PhD.

Twenty-three mentally healthy men and women, average age 27, who took the anti-depressant paroxetine for four weeks as part of the study scored lower on survey questionnaires used to measure hostility and exhibited more engaging and cooperative behavior in puzzle-solving tasks with a partner than they did at the beginning of the study.

In comparison, a matching group of study volunteers who took only an inactive placebo pill did not change by these measures.

"Personality, a set of traits and attributes that characterize individuals and that persist throughout life, has been thought to be about fifty to sixty percent attributable to inheritance, a conclusion based in large part on studies of twins reared either together or apart," Reus explains.

"Inherited aspects of personality by definition must have some biological underpinning, but this is the first controlled study of the effects of a drug on a component of personality in people who are not mentally ill," he says. "Our findings lead us to conclude that different aspects of normal personality may be altered by psychopharmaceuticals that act on distinct nerve pathways in the brain."

Other researchers in previous studies found that, in psychiatric patients, low levels of a signaling molecule, the neurotransmitter serotonin, may be related to psychiatric disorders characterized by hostility and aggression, Reus
'"/>

Contact: UCSF News Services
415-476-2557
University of California - San Francisco
1-Mar-1998


Page: 1 2 3

Related medicine news :

1. Thought for food
2. Common Drug-Capsule Coating Not As Inert As Previously Thought
3. Mayo Clinic Cardiologist Available To Discuss New Guidelines On Treatment Of Stable Angina
4. Time, trust key to successful teen-doctor relationship
5. Bone Cement Used In Total Hip Replacements Slowly Degrades In Body Over Time, According To UCSF Study
6. Changes in ovaries could indicate higher risk of ovarian cancer
7. Changes needed to reduce migrant farm worker exposure to pesticides
8. Changes in allied and auxiliary health care workers training needed for quality of patient care, according to UCSF report
9. American Heart Association Comment: Contributions Of Trends In Survival And Coronary-Event Rates To Changes In Coronary Heart Disease Mortality
10. Psychologist Detects Brain-Activity Changes In Maltreated Kids
11. Changes In Levels Of LDLc From Pre- To Post-Menopausal Years Not Valuable Indicator Of Heart Disease, Reports University Of Pittsburgh Researcher

Post Your Comments:
(Date:7/22/2014)... July 23, 2014 Marietta, Georgia and surrounding ... homes. In an efforts to lower population of needy ... from the Tigg Neuter Project have joined forces. Local ... All proceeds will be presented to the Tigg Neuter ... animal clinic family are excited to attend and host the ...
(Date:7/22/2014)... DocbookMD , a HIPAA-secure mobile communication company, ... largest physician-centric mobile communication solutions in Texas at Memorial ... Created by Austin-based physicians, Tracey Haas, D.O., MPH, and ... into MHMD’s Accountable Care Network to enhance communication between ... put this capability at the fingertips of our physicians ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Obtaining a ... for military veterans who have hands-on medical experience. The ... at Greensboro today announced the launch of an accelerated ... experience. , The new program, the UNCG Veterans Access ... of approximately 24 veterans. With some prior college credit, ...
(Date:7/22/2014)... Air Conditioning & Heating Inc. is ... Daikin comfort pro dealer. This means that the company ... cooling system equipment. Only a select few businesses have ... being approved. , Daikin co-developed an R-410A refrigerant with ... Air Conditioning Market. They are also the inventor of ...
(Date:7/22/2014)... 2014 Dr. Jeremy K. Ueno, of ... have recently discussed the reasons for an increase in ... periodontics profession are seeing the amount of referrals they ... fact, one surgeon reported that over 50% of his ... implants have a very high success rate of up ...
Breaking Medicine News(10 mins):Health News:Marietta Vet Clinic Hosts 2014 Dog Days of Summer Pet Rescue Event 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 4Health News:UNCG School of Nursing Fast-Tracks Medically Trained Veterans 2Health News:Air Conditioning & Heating Inc. Now an Authorized Daikin Comfort Pro Dealer 2Health News:Dr. Jeremy Ueno Can Help Treat Patients That Have Failing Implants 2Health News:Dr. Jeremy Ueno Can Help Treat Patients That Have Failing Implants 3
(Date:7/22/2014)... FRANCISCO , July 22, 2014  Nektar Therapeutics (Nasdaq: ... the second quarter ended June 30, 2014 on Thursday, July ... Howard Robin , president and chief executive officer, will host ... p.m. Eastern Time (ET)/2:00 p.m. Pacific Time (PT). ... the conference call can be accessed through a link that ...
(Date:7/22/2014)... , July 22, 2014 The National Space ... the Center for Space Radiation Research (CSRR) under the ... is an Associate Professor of Pharmaceutical Sciences within the ... Pharmacy Division of Radiation Health. She is located in ... direct a team of investigators working across four U.S. ...
(Date:7/22/2014)... York , July 22, 2014 ... Transparency Market Research "Process Spectroscopy Market (Technology Types - Near ... spectroscopy) Market - Global Industry Analysis, Size, Share, Growth, Trends ... USD 714.5 million in 2012 and is expected to grow ... North America was the largest ...
Breaking Medicine Technology:Nektar to Announce Financial Results for the Second Quarter 2014 on Thursday, July 31, 2014, After Close of U.S.-Based Financial Markets 2Nektar to Announce Financial Results for the Second Quarter 2014 on Thursday, July 31, 2014, After Close of U.S.-Based Financial Markets 3Boerma Led UAMS Team to Establish NSBRI's Center for Space Radiation Research (CSRR) 2Boerma Led UAMS Team to Establish NSBRI's Center for Space Radiation Research (CSRR) 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 2Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 4
Cached News: