HOME >> MEDICINE >> NEWS
Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant

The degree to which a person is easy-going or irritable--a personality trait thought to be one of the stable touchstones of identity--can be shifted more toward the easy-going side by a drug used to treat depression, University of California San Francisco researchers report.

The evidence that drugs can act on the brain to change once-stable measures of personality is published in the March issue of the American Journal of Psychiatry by a UCSF research team led by Victor Reus, MD, and Owen Wolkowitz, MD, professors of psychiatry at UCSF, and by postdoctoral fellow Brian Knutson, PhD.

Twenty-three mentally healthy men and women, average age 27, who took the anti-depressant paroxetine for four weeks as part of the study scored lower on survey questionnaires used to measure hostility and exhibited more engaging and cooperative behavior in puzzle-solving tasks with a partner than they did at the beginning of the study.

In comparison, a matching group of study volunteers who took only an inactive placebo pill did not change by these measures.

"Personality, a set of traits and attributes that characterize individuals and that persist throughout life, has been thought to be about fifty to sixty percent attributable to inheritance, a conclusion based in large part on studies of twins reared either together or apart," Reus explains.

"Inherited aspects of personality by definition must have some biological underpinning, but this is the first controlled study of the effects of a drug on a component of personality in people who are not mentally ill," he says. "Our findings lead us to conclude that different aspects of normal personality may be altered by psychopharmaceuticals that act on distinct nerve pathways in the brain."

Other researchers in previous studies found that, in psychiatric patients, low levels of a signaling molecule, the neurotransmitter serotonin, may be related to psychiatric disorders characterized by hostility and aggression, Reus
'"/>

Contact: UCSF News Services
415-476-2557
University of California - San Francisco
1-Mar-1998


Page: 1 2 3

Related medicine news :

1. Thought for food
2. Common Drug-Capsule Coating Not As Inert As Previously Thought
3. Mayo Clinic Cardiologist Available To Discuss New Guidelines On Treatment Of Stable Angina
4. Time, trust key to successful teen-doctor relationship
5. Bone Cement Used In Total Hip Replacements Slowly Degrades In Body Over Time, According To UCSF Study
6. Changes in ovaries could indicate higher risk of ovarian cancer
7. Changes needed to reduce migrant farm worker exposure to pesticides
8. Changes in allied and auxiliary health care workers training needed for quality of patient care, according to UCSF report
9. American Heart Association Comment: Contributions Of Trends In Survival And Coronary-Event Rates To Changes In Coronary Heart Disease Mortality
10. Psychologist Detects Brain-Activity Changes In Maltreated Kids
11. Changes In Levels Of LDLc From Pre- To Post-Menopausal Years Not Valuable Indicator Of Heart Disease, Reports University Of Pittsburgh Researcher

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... MemoryCare.com, a comprehensive resource for ... Care Facilities in Louisville, KY. The guide identifies 17 memory care communities based ... the Alzheimer’s Association , 5.6 million people age 65 and older are ...
(Date:9/1/2020)... ... September 01, 2020 , ... Feeding Matters , the first organization in ... Disorder (PFD), is pleased to announce that the U.S. Centers for Disease Control and ... in the next edition of the U.S. International Classification of Diseases (ICD ) ...
(Date:8/31/2020)... ... ... found out your dear friend has cancer? , It’s hard to hear your doctor say ... diagnosis. Once the shock wears off, the questions and fears can be overwhelming. , How ... to help? Words are failing me. I’m scared. I want to DO something. , We’ve ...
(Date:8/31/2020)... Calif. (PRWEB) , ... August 31, 2020 , ... ... of business support services to dental groups in the United States, today announced ... the community of Beaumont, CA. , Patients will enjoy convenient hours, a ...
(Date:8/31/2020)... ... 31, 2020 , ... Bonde Innovations, LLC, a venture-backed developer ... failure, today announced that the company has been awarded a Phase 1 Small ... Heart, Lung, and Blood Institute of the National Institutes of Health (NIH). The ...
Breaking Medicine News(10 mins):
(Date:8/31/2020)... ... 31, 2020 , ... Welltech1, the first Israeli VC fund ... $400,000 in PopBase, one of two start-ups that beat 152 companies in the ... , The competition was part of the GWI’s The Wellness Moonshot: A ...
(Date:8/28/2020)... ... August 28, 2020 , ... Cano ... medical centers in Florida and San Antonio is happy to announce that it ... centers. , In this capacity he will serve as community advisor, advertising talent, ...
(Date:8/27/2020)... ... August 27, 2020 , ... Austin Oral Surgery – ... pleased to announce Dr. David Szalay, DDS, MD, has joined the practice. An accomplished ... the new Pflugerville office, which is scheduled to open this fall. The new office ...
Breaking Medicine Technology:
Cached News: