HOME >> MEDICINE >> NEWS
Pet scans could provide insight into HIV-1 progression

An article and a research letter in this week's issue of THE LANCET provide preliminary data suggesting that positron emission tomography (PET) scans could identify the effect of HIV-1 infection on the body's lymphatic system. Authors of the studies suggest that activation of specific lymph nodes could determine the stage of HIV-1 infection, with implications for possible surgical or radiological treatment of lymph nodes as a future option in addition to antiretroviral therapy in the management of HIV/AIDS.

Lymphocyte activation-associated with vaccination or infection-can be measured by PET. David Schwartz and Sujatha Iyengar from the Johns Hopkins University Bloomberg School of Hygiene and Public Health, USA, and colleagues studied 12 people with recent HIV-1 infection and 11 people with chronic HIV-1 infection. Cervical and axillary node activation was identified in people with both early and chronic infection; patients with long-term infection who had not progressed to AIDS had small numbers of persistently active nodes, most of which were surgically accessible. PET assessment correlated well with genetic assessment of viral activity done by polymerase chain reaction.

David H Schwartz comments: "With the development of intraoperative PET probes for individual node detection, the feasibility of excisional biopsy to study and remove foci of persistent infection should be investigated. Although many systemic sites from which latent virus could re-activate would be left, re-activation might not occur for months or years after removal of the active nodes, thereby allowing extended interruptions of treatment."

Authors of a research letter (p 959) report similar findings for whole-body PET images from 15 patients with HIV-1. Assessment of PET scans showed distinct lymphoid tissue activation in the head and neck during acute disease, a generalised pattern of peripheral lymph-node activation at mid-stages, and involvement of abdominal lymph node
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
18-Sep-2003


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Pet scans could provide insight into HIV progression

(Date:2/28/2015)... The Heart Fit Clinic started doing External ... machine. The Heart Fit Clinic is also selling the ... model. The goal is to scale the business to ... buy External Counterpulsation machines can be difficult ... this process and achieve the desired results. , ...
(Date:2/28/2015)... Indosoft Inc , developers of Q-Suite, a ... to announce the development of Q-Suite 5.9. Building off ... Q-Suite, this new version will include enhancements to existing ... to the leading edge call center software. General availability ... features to enhance security and protection. Administrators will be ...
(Date:2/28/2015)... St. Louis, MO (PRWEB) February 28, 2015 ... a leading provider of outsourced sales, marketing and ... announces their client, BIOTA Botanicals, is bringing its ... , Celebrated worldwide, BIOTA Botanicals’ products are specifically ... the herbal care experts, BIOTA is committed to ...
(Date:2/28/2015)... (PRWEB) February 28, 2015 How ... Supportive? Strategic? , There are all kinds of ... To raise awareness of the advantages and applications ... PeopleKeys is launching a new product this spring ... better understand the connection between personality type, leadership, ...
(Date:2/28/2015)... 2015 Javon Bea Mercy Health ... Hospital as stroke capable by the State of Illinois, ... to Mercy Harvard Hospital. , The hospital was required ... ability to treat stroke according to national standards of ... stroke patients to bypass hospitals not designated as an ...
Breaking Medicine News(10 mins):Health News:Clinicians Can Now Purchase External Counterpulsation with Heart Fit Clinic 2Health News:Indosoft Proudly Announces Q-Suite 5.9 Call Center Software for Asterisk 2Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 2Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 3Health News:PeopleKeys Launches The Leadership Report 2Health News:PeopleKeys Launches The Leadership Report 3Health News:Mercy Harvard Hospital Recognized as Leader in Stroke Care - Javon Bea 2
(Date:2/27/2015)... , Feb. 27, 2015 /CNW/ - Covalon Technologies Ltd. (the ... company, today announced financial results for its first quarter ... three months ended December 31, 2014, revenue was $1,336,685. ... was $229,820 or $0.02 per share.  ... "I am very pleased with the significant progress we ...
(Date:2/27/2015)... -- Uroplasty, Inc. (NASDAQ: UPI ), a medical device ... to treat voiding dysfunctions, today announced that it will ... March 10, 2015. Rob Kill , President and ... will present at 4:00 p.m. Pacific Time and meet ... the Ritz Carlton in Laguna Niguel, CA. ...
(Date:2/26/2015)... Feb. 27, 2015  Finesse expands office in ... announced the expansion of its operations in ... mid-March and access for customers is expected shortly afterward. ... located adjacent to the current office, the new premises ... team and allow Finesse to bring on more service ...
Breaking Medicine Technology:Covalon Announces First Quarter Financial Results 2Covalon Announces First Quarter Financial Results 3Uroplasty to Participate in the 27th Annual ROTH Conference 2New Finesse Office in United Kingdom 2
Cached News: