HOME >> MEDICINE >> NEWS
Pet scans could provide insight into HIV-1 progression

An article and a research letter in this week's issue of THE LANCET provide preliminary data suggesting that positron emission tomography (PET) scans could identify the effect of HIV-1 infection on the body's lymphatic system. Authors of the studies suggest that activation of specific lymph nodes could determine the stage of HIV-1 infection, with implications for possible surgical or radiological treatment of lymph nodes as a future option in addition to antiretroviral therapy in the management of HIV/AIDS.

Lymphocyte activation-associated with vaccination or infection-can be measured by PET. David Schwartz and Sujatha Iyengar from the Johns Hopkins University Bloomberg School of Hygiene and Public Health, USA, and colleagues studied 12 people with recent HIV-1 infection and 11 people with chronic HIV-1 infection. Cervical and axillary node activation was identified in people with both early and chronic infection; patients with long-term infection who had not progressed to AIDS had small numbers of persistently active nodes, most of which were surgically accessible. PET assessment correlated well with genetic assessment of viral activity done by polymerase chain reaction.

David H Schwartz comments: "With the development of intraoperative PET probes for individual node detection, the feasibility of excisional biopsy to study and remove foci of persistent infection should be investigated. Although many systemic sites from which latent virus could re-activate would be left, re-activation might not occur for months or years after removal of the active nodes, thereby allowing extended interruptions of treatment."

Authors of a research letter (p 959) report similar findings for whole-body PET images from 15 patients with HIV-1. Assessment of PET scans showed distinct lymphoid tissue activation in the head and neck during acute disease, a generalised pattern of peripheral lymph-node activation at mid-stages, and involvement of abdominal lymph node
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
18-Sep-2003


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. Pet scans detect brain differences in people at risk for Alzheimers
5. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
6. MRI scans could be acceptable alternative to x-rays
7. Chemical brain scans may help reassure brain tumor patients
8. Lung tumor therapies improved by combining CT and PET scans
9. New study supports use of PET scans in early diagnosis of Alzheimers disease
10. Brain scans show how placebo eases pain
11. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ... today the introduction of an innovative new design of the shoulder pad. The ... get maximum comfort while controlling your pain while using cold therapy. By utilizing ice ...
(Date:10/12/2017)... ... ... Asante, a nationally recognized health system in southern Oregon, ... health joint venture through an agreement, effective October 1, 2017, to create AccentCare ... company with Asante, delivering clinically integrated care, for the past eight years. This ...
(Date:10/12/2017)... ANGELES (PRWEB) , ... October 12, 2017 , ... ... Parsa Mohebi Hair Restoration, has recently contributed a medical article to the newly ... on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... , ... October 12, 2017 , ... Leading pediatric oncology ... in Washington, D.C., for the 49th Congress of the International Society of Paediatric ... President of the Center for Cancer and Blood Disorders at Children’s National, ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Divoti USA will engrave and process all non-coated ... latest FDA requirements, which stipulates new criteria regarding medical device manufacture ... Medical ID jewelry such as Medical ID Bracelets, can rest assured ... of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving process ...
(Date:10/11/2017)... 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), ... in Las Piedras, Puerto Rico , ... Following a ... sustained minor structural damage, temporary loss of power and ... been completed, manufacturing operations have resumed, and the company ...
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
Breaking Medicine Technology:
Cached News: