HOME >> MEDICINE >> NEWS
Pet scans detect brain differences in people at risk for Alzheimer's

Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

Because researchers believe that Alzheimer's disease starts changing the brain years before any symptoms appear, the disease may be most amenable to treatment in these pre-clinical stages. If so, detecting the early changes will be crucial for future therapies.

People who carry the genetic risk factor, the 4 allele of the Apolipoprotein (APOE) gene, have higher risk of developing the disease than non-carriers and usually show symptoms earlier.

"It is possible that what we're seeing in the APOE- 4 carriers are early changes in the brain caused by Alzheimer's disease," says the study's senior author, Yaakov Stern, Ph.D., of CUMC's Taub Institute and Sergievsky Center.

But he and the study's first author, Nikolaos Scarmeas, M.D., caution that more research is needed before it's known for certain if the difference is an early sign of Alzheimer's. "It's also possible that the brain differences we see are related to the APOE gene but are not necessarily directly related to incipient Alzheimer's," says Dr. Scarmeas, a neurologist in the Taub Institute, Sergievsky Center and neurology department. "Even so, the differences we've found may provide information on how the 4 allele predisposes carriers to Alzheimer's disease."

The present study appears in the Nov.-Dec. 2004 issue of the American Journal of Geriatric Psychiatry.

About the Study
The researchers looked at six people who carried the APOE- 4 risk factor and 26 non-carriers.

None of the 32 participants, mostly in their 60s and 70s, had any signs of dementia or memory deficits and the two groups could not be distinguished from one another by standard cognitive tests.

PET scans taken while the subjects were pe
'"/>

Contact: Karen Zipern
kz2110@columbia.edu
212-305-9746
Columbia University Medical Center
19-Nov-2004


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
5. MRI scans could be acceptable alternative to x-rays
6. Chemical brain scans may help reassure brain tumor patients
7. Lung tumor therapies improved by combining CT and PET scans
8. New study supports use of PET scans in early diagnosis of Alzheimers disease
9. Brain scans show how placebo eases pain
10. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors
11. CT scans find tiny bladder, kidney & urinary cancers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2020)... ... , ... Winemaker Grant Long Jr. is introducing three Toilet Paper Reserve wines. ... in these complicated times,” he said, in announcing the new wines. The wines are ... and Red Wine Blend are sourced in the Napa Valley; the Grenache comes from ...
(Date:5/21/2020)... ... May 21, 2020 , ... In response to the ... that allows users to open swing-style doors without using their hands or fingertips. ... to pull the door open using their forearm, wrist or elbow when entering or ...
(Date:5/21/2020)... ... May 21, 2020 , ... Fujirebio ... in cancer biomarker assays, announced today that Cigna has added ROMA® (Risk of ... global health service company dedicated to improving the health, well-being, and peace of ...
(Date:5/21/2020)... ... ... A Safe Haven Foundation (ASHF) has been selected as one of 26 ... Fund. The fund was created in March to help nonprofits with their immediate response ... vulnerable populations in hard-hit communities. , “We are humbled and honored to be ...
(Date:5/21/2020)... ... 21, 2020 , ... In response to Michigan Governor Gretchen ... 28th and all businesses will be required to have covid-19 employee screening, AmeriCare ... As an essential business, AmeriCare Medical began this precautionary process in early March, ...
Breaking Medicine News(10 mins):
(Date:5/30/2020)... ... May 29, 2020 , ... Impiger Technologies, a Texas ... solution People1 Care to help organizations safely return their employees to ... normal’ through daily wellness screenings, social distancing support, and contact tracing at work. ...
(Date:5/30/2020)... ... May 30, 2020 , ... Pregnancy ... host of new issues related to COVID-19. Recently, Wellness Expert Jamie Hess teamed ... moms support their pregnancy and postpartum. , A video accompanying this announcement ...
(Date:5/28/2020)... ... May 28, 2020 , ... Reinforcing its commitment ... latest white paper, Caring for our Children: A Look at Patient Experience in ... pediatric settings and highlights key findings to help organizations achieve their experience goals. ...
Breaking Medicine Technology:
Cached News: