HOME >> MEDICINE >> NEWS
Pet scans detect brain differences in people at risk for Alzheimer's

Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

Because researchers believe that Alzheimer's disease starts changing the brain years before any symptoms appear, the disease may be most amenable to treatment in these pre-clinical stages. If so, detecting the early changes will be crucial for future therapies.

People who carry the genetic risk factor, the 4 allele of the Apolipoprotein (APOE) gene, have higher risk of developing the disease than non-carriers and usually show symptoms earlier.

"It is possible that what we're seeing in the APOE- 4 carriers are early changes in the brain caused by Alzheimer's disease," says the study's senior author, Yaakov Stern, Ph.D., of CUMC's Taub Institute and Sergievsky Center.

But he and the study's first author, Nikolaos Scarmeas, M.D., caution that more research is needed before it's known for certain if the difference is an early sign of Alzheimer's. "It's also possible that the brain differences we see are related to the APOE gene but are not necessarily directly related to incipient Alzheimer's," says Dr. Scarmeas, a neurologist in the Taub Institute, Sergievsky Center and neurology department. "Even so, the differences we've found may provide information on how the 4 allele predisposes carriers to Alzheimer's disease."

The present study appears in the Nov.-Dec. 2004 issue of the American Journal of Geriatric Psychiatry.

About the Study
The researchers looked at six people who carried the APOE- 4 risk factor and 26 non-carriers.

None of the 32 participants, mostly in their 60s and 70s, had any signs of dementia or memory deficits and the two groups could not be distinguished from one another by standard cognitive tests.

PET scans taken while the subjects were pe
'"/>

Contact: Karen Zipern
kz2110@columbia.edu
212-305-9746
Columbia University Medical Center
19-Nov-2004


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
5. MRI scans could be acceptable alternative to x-rays
6. Chemical brain scans may help reassure brain tumor patients
7. Lung tumor therapies improved by combining CT and PET scans
8. New study supports use of PET scans in early diagnosis of Alzheimers disease
9. Brain scans show how placebo eases pain
10. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors
11. CT scans find tiny bladder, kidney & urinary cancers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... Manhattan New york (PRWEB) , ... April 28, ... ... is pleased to announce that Aditya Patel M.D. has joined the revolutionary endoscopic ... fellowship training and board certification in Interventional Pain Medicine. The patented, revolutionary eDiscSculpt ...
(Date:4/28/2017)... Harbor, Md. (PRWEB) , ... April 28, 2017 ... ... Care Association of America (UCAOA) and College of Urgent Care Medicine will host ... 2017 workshops, sessions and speakers will help those in the industry adapt to ...
(Date:4/28/2017)... ... ... Bill Howe started his sewer and drain company in 1980 focusing heavily ... team, the Bill Howe brand was born and they began cultivating their mission to ... the San Diego community in which they worked, lived and were raising their daughters. ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... the North East region. Côté has 20+ years of experience within the beauty ... Côté worked with an array of high-end cosmetic brands, retail brands and outlets ...
(Date:4/28/2017)... San Mateo, CA (PRWEB) , ... April 28, 2017 , ... ... Bay Area cities as diverse as Millbrae, Burlingame, and Palo Alto, is proud to ... tags allow interested persons to bookmark and read organized content on topics such as ...
Breaking Medicine News(10 mins):
(Date:4/25/2017)... Endo International plc (NASDAQ: ENDP ) will ... its senior management team will host a conference call and webcast ... The dial-in number to access the call is U.S./ ... passcode is 6086379. Please dial in 10 minutes prior to the ... of the call will be available from May 9, 2017 at ...
(Date:4/20/2017)...  Cogentix Medical, Inc. (NASDAQ: CGNT), a global ... Uro/Gyn and Gynecology markets with innovative and proprietary ... the Company as Senior Vice President, Marketing & ... Keswani will report directly to Darin Hammers ... is delighted that Ash has joined the Cogentix ...
(Date:4/20/2017)... 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), a ... significant unmet medical needs, today announced that it ... product development program, based on its proprietary self-delivering ... Dermatology (SID) 76 th Annual Meeting.  The ... sciences relevant to skin health and disease through ...
Breaking Medicine Technology:
Cached News: