HOME >> MEDICINE >> NEWS
Pet scans detect brain differences in people at risk for Alzheimer's

Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

Because researchers believe that Alzheimer's disease starts changing the brain years before any symptoms appear, the disease may be most amenable to treatment in these pre-clinical stages. If so, detecting the early changes will be crucial for future therapies.

People who carry the genetic risk factor, the 4 allele of the Apolipoprotein (APOE) gene, have higher risk of developing the disease than non-carriers and usually show symptoms earlier.

"It is possible that what we're seeing in the APOE- 4 carriers are early changes in the brain caused by Alzheimer's disease," says the study's senior author, Yaakov Stern, Ph.D., of CUMC's Taub Institute and Sergievsky Center.

But he and the study's first author, Nikolaos Scarmeas, M.D., caution that more research is needed before it's known for certain if the difference is an early sign of Alzheimer's. "It's also possible that the brain differences we see are related to the APOE gene but are not necessarily directly related to incipient Alzheimer's," says Dr. Scarmeas, a neurologist in the Taub Institute, Sergievsky Center and neurology department. "Even so, the differences we've found may provide information on how the 4 allele predisposes carriers to Alzheimer's disease."

The present study appears in the Nov.-Dec. 2004 issue of the American Journal of Geriatric Psychiatry.

About the Study
The researchers looked at six people who carried the APOE- 4 risk factor and 26 non-carriers.

None of the 32 participants, mostly in their 60s and 70s, had any signs of dementia or memory deficits and the two groups could not be distinguished from one another by standard cognitive tests.

PET scans taken while the subjects were pe
'"/>

Contact: Karen Zipern
kz2110@columbia.edu
212-305-9746
Columbia University Medical Center
19-Nov-2004


Page: 1 2

Related medicine news :

1. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
2. Stanford study questions accuracy of ads for body scans
3. New technique scans electrical brainscape
4. 3D neutron-based medical imaging, 4D lung scans, and hitting a moving tumor
5. MRI scans could be acceptable alternative to x-rays
6. Chemical brain scans may help reassure brain tumor patients
7. Lung tumor therapies improved by combining CT and PET scans
8. New study supports use of PET scans in early diagnosis of Alzheimers disease
9. Brain scans show how placebo eases pain
10. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors
11. CT scans find tiny bladder, kidney & urinary cancers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... Gastro Health (“GH”) ... prep patients for colonoscopy at the HyGIeaCare® Center that is to be located ... , The HyGIeaCare® Prep, cleared by the U.S. Food and Drug ...
(Date:3/24/2017)... ... March 24, 2017 , ... Judy Buchanan, co-owner ... in Frederick, MD. Judy says, “I am passionate about sharing Reiki as a ... very difficult and challenging time.” , A Certified Medical Reiki™ Master trained by ...
(Date:3/24/2017)... ... March 24, 2017 , ... “End Time GPS”: a ... will interrelate. “End Time GPS” is the creation of published author, Wesley Gerboth, ... working on military munitions and space-vehicle projects. Now, at age ninety-one, he shares the ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The ... about real people of God in congregations across the United States. “The ... minister ordained in 1964 who has served congregations in seven states throughout his ...
(Date:3/23/2017)... & Seattle, WA (PRWEB) , ... March 23, 2017 , ... ... health emergency and now estimates that there could be four million Zika-related cases in ... epidemics to date with numbers of US cases reported per year skyrocketing to an ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , Mar. 24, 2017 Research and Markets has ... Report" report to their offering. ... This report analyzes the worldwide markets for Dental Implants in ... Canada , Japan , Europe ... , and Rest of World. Annual estimates and forecasts ...
(Date:3/24/2017)... , March 24, 2017 FinancialBuzz.com ... ... leading publisher of cannabis market research, the legal cannabis market ... CAGR through 2021, despite conflicting signals from the current presidential ... out that the two biggest drivers of growth in this ...
(Date:3/24/2017)... DUBLIN , Mar 24, 2017 Research ... in Drug Discovery and Diagnostics, 2017 - 2035" report to ... The ... current landscape and future outlook of the growing market of deep ... data revolution, deep learning algorithms have emerged as a novel solution ...
Breaking Medicine Technology:
Cached News: