HOME >> MEDICINE >> NEWS
Ph.D. Degree Research Results In Patent For Low-Cost Pharmaceutical Filters Made From Seafood Waste

(Blacksburg, Va., May 24, 1999) Jason Todd of Newport News, Va., earned a patent for his Ph.D. degree research even before receiving his degree in wood science from Virginia Tech.

Todd's dissertation research has resulted in a new, low-cost material for purifying proteins, such as to capture antibodies from blood serum or cell cultures. Such antibodies are used in diagnosis and treatment of diseases, as well as testing for drug abuse.

Todd, along with Wolfgang Glasser, professor of wood science in the College of Natural Resources, and Swapan Roy of LigoChem Inc., who received a patent (No. 5,770,712, June 23, 1998) for "Crosslinked hydrogel beads from chitosan," were recognized for their work by Virginia Tech Intellectual Properties, Inc. last week.

Chitosan is a modified form of chitin, a structural component in crab and shrimp shells. "So chitosan can be isolated from seafood waste," Todd explains. The material is formed into hydrogel beads, which are mostly water or "a highly swollen polymer network" and used in pharmaceutical separation processes. The beads are coated with "chemical functional groups" or "ligands" that grab or attract the target proteins such as antibodies or antigens.

Chitosan beads are not new. Neither is the process of using beads in separation. "The ligand is a group of atoms that interacts with the target molecule, resulting in attraction. A positively-charged ligand will attract a negatively-charged protein, for example, since opposite charges attract. Other types of interactions, such as hydrophobic interactions, can be used as well.," says Todd.

"The basis of the patent is the way we attach the ligand to the beads," he says. "We use a spacer arm to separate the ligand from the chitosan molecule. Having the space between the ligand and the supporting chitosan chain results in better selectivity -- better control in terms of getting the proteins you want to stick to your molecular structure without getting the one
'"/>

Contact: Wolfgang Glasser or Jason Todd
wglasser@vt.edu
540-231-4403
Virginia Tech
24-May-1999


Page: 1 2 3

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Research offers hope of new treatments for liver damage
3. Research suggests possible blood test for multiple sclerosis
4. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
5. 2005 Award for Basic Research in Biological Mineralization
6. 2005 Craniofacial Biology Research Award
7. 2005 Research in Dental Caries Award
8. 2005 Research in Prosthodontics and Implants Award
9. 2005 Basic Research in Periodontal Disease Award
10. 2005 Research in Oral Biology Award
11. 2005 Pulp Biology Research Award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/16/2018)... ... October 16, 2018 , ... ... and clinical research networking-technology company founded by patient-survivors, and The Avoca Group, ... in the clinical trial execution process, today announced its mutual collaboration that ...
(Date:10/13/2018)... ... 13, 2018 , ... The National Fitness Foundation, the official ... Burley as its new Vice President of Partnerships & Marketing. , ... the mission of the President's Council by generating private sector investments and partnerships ...
(Date:10/11/2018)... ... October 11, 2018 , ... ... medical clinic of all sizes and specialties. PrognoCIS , their Health IT ... for their patients. , Greater Houston Healthconnect (GHH), the region’s health information exchange ...
(Date:10/6/2018)... ... 2018 , ... Jose Rodriguez- Feliz M.D is a board–certified ... well known for their exclusivity, and luxurious lifestyle publication is privileged to present ... to the Haute Living network. , Haute Beauty consists of a prominent ...
(Date:10/5/2018)... ... 2018 , ... The Congress of Neurological Surgeons is pleased ... which currently includes 2-D and 3-D videos. Surgical Theater and NEUROSURGERY® Publications will ... number of surgical videos submitted to the journal will be invited to be ...
Breaking Medicine News(10 mins):
(Date:10/5/2018)... MCLEAN, Va. (PRWEB) , ... October 05, 2018 ... ... pleased to announce that Lissa Goldenstein has been named Chair-Elect of the Board ... the association’s strategic initiatives. RESOLVE is dedicated to ensuring that all people challenged ...
(Date:10/3/2018)... ... 2018 , ... Friends of Sheba Medical Center, Tel HaShomer and ... on Sunday evening, October 14th, which will celebrate 70 years of saving lives at ... treated members of the Israel Defense Forces (IDF) and civilians wounded during the War ...
(Date:10/3/2018)... ... October 03, 2018 , ... Arizona Arthritis & Rheumatology ... TSI Healthcare, a national leader in the sales and support of ... selected to be the sole software and support provider for Arizona Arthritis & ...
Breaking Medicine Technology:
Cached News: